초록 ▼

An apparatus and method for carrying out and monitoring the progress and properties of multiple reactions is disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional expe

An apparatus and method for carrying out and monitoring the progress and properties of multiple reactions is disclosed. The method and apparatus are especially useful for synthesizing, screening, and characterizing combinatorial libraries, but also offer significant advantages over conventional experimental reactors as well. The apparatus generally includes multiple vessels for containing reaction mixtures, and systems for controlling the stirring rate and temperature of individual reaction mixtures or groups of reaction mixtures. In addition, the apparatus may include provisions for independently controlling pressure in each vessel, and a system for injecting liquids into the vessels at a pressure different than ambient pressure. In situ monitoring of individual reaction mixtures provides feedback for process controllers, and also provides data for determining reaction rates, product yields, and various properties of the reaction products, including viscosity and molecular weight.

대표청구항 ▼

[ What is claimed is:] [1.]1. An apparatus for parallel processing of reaction mixtures comprising:vessels sealed against fluid communication with one another and adapted for containing the reaction mixtures at pressures different than ambient pressures;a stirring system for agitating the reaction m

[ What is claimed is:] [1.]1. An apparatus for parallel processing of reaction mixtures comprising:vessels sealed against fluid communication with one another and adapted for containing the reaction mixtures at pressures different than ambient pressures;a stirring system for agitating the reaction mixtures;a temperature control system for regulating the temperature of the reaction mixtures in the vessels; andan injection system comprising a fluid delivery probe movable from one vessel to another vessel for effecting the introduction of a fluid into each of the vessels at a pressure different than ambient pressure, said injection system being operable for preventing leakage of fluid under pressure from each vessel during said introduction by said fluid delivery probe and after said probe has moved to another vessel.