초록 ▼

The present invention provides devices and methods for stabilizing bicarbonate-based solutions for peritoneal dialysis or hemofiltration. The bicarbonate-based solutions of the present invention are formulated and stored in at least two parts--an alkaline bicarbonate concentrate and an acidic concen

The present invention provides devices and methods for stabilizing bicarbonate-based solutions for peritoneal dialysis or hemofiltration. The bicarbonate-based solutions of the present invention are formulated and stored in at least two parts--an alkaline bicarbonate concentrate and an acidic concentrate. The alkaline bicarbonate concentrate is adjusted to have a pH of about 8.6 to 10.0. The acidic concentrate is adjusted to have a stable, acidic pH ranging from about 1.0 to 3.0. Upon mixing, although some variation in the pH of the mixed bicarbonate solution exists, the inventors have discovered that with the appropriate selection of the parameters of the concentrates, the pH of the mixed solution is always within an acceptable physiological range.

대표청구항 ▼

[ We claim:] [1.]1. A two-part bicarbonate containing solution, the solution comprising:a first part housed in a first container, the first part including an alkaline bicarbonate concentrate having a pH ranging from 8.6 to 10.0;a second part housed in a second container, the second part including an

[ We claim:] [1.]1. A two-part bicarbonate containing solution, the solution comprising:a first part housed in a first container, the first part including an alkaline bicarbonate concentrate having a pH ranging from 8.6 to 10.0;a second part housed in a second container, the second part including an acidic concentrate having a pH ranging from about 1.0 to 3.0, the pH of the acidic concentrate effective to obtain, when the first part and the second part are mixed together, a mixed solution having a pH ranging from 6.5 to 7.6.