초록 ▼

Superoxide dismutase (SOD), preferably rhSOD, is used in liposomes, optionally mixed with hyaluronic acid and/or at least one physiologically acceptable carrier, and other optional additives, to prepare a pharmaceutical composition useful against increased concentrations of superoxide radicals and/o

Superoxide dismutase (SOD), preferably rhSOD, is used in liposomes, optionally mixed with hyaluronic acid and/or at least one physiologically acceptable carrier, and other optional additives, to prepare a pharmaceutical composition useful against increased concentrations of superoxide radicals and/or the damage caused thereby. The compositions are administered topically, preferably as gels or ointments, to prevent and/or heal human fibrotic tissue degeneration diseases, in particular induratio penis plastica (Peyronie's Disease).

대표청구항 ▼

[ What is claimed is:] [1.]1. A method for the prophylactic or therapeutic intervention of a pathological condition affecting a human body or part thereof, wherein said condition is susceptible to adminstration of superoxide dismutase, the method comprising topically administering to the human body

[ What is claimed is:] [1.]1. A method for the prophylactic or therapeutic intervention of a pathological condition affecting a human body or part thereof, wherein said condition is susceptible to adminstration of superoxide dismutase, the method comprising topically administering to the human body or part thereof a pharmaceutical composition comprising a low-fat or fat free carrier together with recombinant human Cu, Zn-SOD(rhSOD) in unilamellar liposomes having an average diameter of 200 nm or less in an amount effective for penetrating from the outside into deeper lying tissue layers of the body or part thereof, to prevent or relieve said pathological condition, and wherein said pathological condition is induratio penis plastica (IPP).