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Reparatives for ultraviolet radiation skin damage 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C07K-014/475
  • A61K-038/18
  • A61K-007/48
출원번호 US-0728948 (1996-10-11)
발명자 / 주소
  • Theodore Hersh
  • Michael A. Warshaw
출원인 / 주소
  • Thione International, Inc.
대리인 / 주소
    Malcolm B. Wittenberg
인용정보 피인용 횟수 : 30  인용 특허 : 10

초록

A composition of L-glutathione (reduced) and selenium and an epidermal growth factor in a topical carrier and method of using the composition to reduce and repair ultraviolet radiation-induced skin damage, both acute injury (sunburn) and chronic damage (photoaging and cutaneous malignancies).

대표청구항

1. A topical pharmaceutical composition for reducing the effects of ultraviolet radiation induced skin damage comprising as active ingredients an amount of reduced L-glutathione, selenium and epidermal growth factor to reduce ultraviolet radiation induced skin damage in a suitable carrier for topica

이 특허에 인용된 특허 (10)

  1. Neigut Stanley J. (10 Red Rowan La. Plymouth Meeting PA 19462), Composition for the topical treatment of skin damage.
  2. Powell Maxwell M. (Great Neck NY), Compositions suitable for human topical application including a growth factor and/or related materials.
  3. Cavazza Claudio (Rome ITX) Cavazza Paolo (Rome ITX), Esters of L-carnitine and alkanoyl L-carnitines with glycolic acid or esters thereof and pharmaceutical compositions con.
  4. Ohlenschlager Gerhard,DEX, Pharmaceutical therapeutic use of glutathione derivative.
  5. Nicola Massimo (Pavia ITX) Inglesi Marco (Milan ITX) Fregnan Giancarlo B. (Milan ITX) Vandoni Guido (Correzzana ITX), Salts of a glutathione alkylester and anaminoacids.
  6. Cavazza Claudio (Rome ITX), Salts of-carnitine and alkanoyl L-carnitines and process for preparing same.
  7. Okuyama Shinichi (Miyagi JPX) Mishina Hitoshi (Miyagi JPX) Furuse Kazumaro (Tokyo JPX) Murotani Isao (Kanagawa JPX), Therapeutic method for treating radiation ulcers.
  8. Hersh Theodore (Atlanta GA) Warshaw Michael A. (Savannah GA), X-ray induced skin damage protective composition.
  9. Hersh Theodore ; Warshaw Michael A., X-ray induced skin damage protective composition.
  10. Levin Robert H. (11127 Jardin Pl. Cincinnati OH 45241) Keller Stephen J. (1334 Edwards Rd. Cincinnati OH 45208), Yeast-derived epidermal growth factor/urogastrone-like products.

이 특허를 인용한 특허 (30)

  1. Chen,Guan Jie; Lantz,Robert Clark; Solyom,Aniko M.; Timmermann,Barbara N.; Jolad,Shivanand D., Anti-inflammatory activity of a specific turmeric extract.
  2. Baschong, Werner; Reich, Oliver; Mongiat, Sébastien, Anti-radical agents.
  3. Sauermann, Gerhard; Schreiner, Volker; Döring, Thomas; Siefken, Wilfried; Gatermann, Cornelia; Carstensen, Stefanie; Biergiesser, Helga, Cosmetic and dermatological preparations containing carnitine for treating and actively preventing dry skin and other negative alterations in the physiological homeostasis of healthy skin.
  4. Ella, Krishna Murthy; Vellimedu, Srinivas Kannappa, Epidermal growth factor compositions.
  5. Mammone, Thomas; Muizzuddin, Neelam; Schnittger, Steven F., Extracts from black yeast for whitening skin.
  6. Mammone,Thomas; Muizzuddin,Neelam; Schnittger,Steven F., Extracts from black yeast for whitening skin.
  7. Mentlik, Anton A.; Swanzy, James, Glyceryl and glycol acid compounds.
  8. Mentlik, Anton A.; Swanzy, James, Glyceryl and glycol acid compounds.
  9. Mentlik, Anton A.; Swanzy, James, Glyceryl and glycol acid compounds.
  10. Mentlik, Anton A.; Swanzy, James, Glyceryl and glycol acid compounds.
  11. Dooley, Thomas P.; Curto, Ernest V., Inhibitors of melanocyte tyrosinase as topical skin lighteners.
  12. Chang, Yunik; Lathrop, Robert; Böhm, Erwin; Gander-Meisterernst, Irene; Greger, Regina; Holldack, Johanna; Moebius, Ulrich, Medicament for the treatment of viral skin and tumour diseases.
  13. Chang, Yunik; Lathrop, Robert; Böhm, Erwin; Gander-Meisterernst, Irene; Greger, Regina; Holldack, Johanna; Moebius, Ulrich, Medicament for the treatment of viral skin and tumour diseases.
  14. Dittrich, Wayne, Method and composition for treating burned skin.
  15. Dittrich, Wayne, Method and composition for treating sunburned skin.
  16. Liao, Shutsung; Hiipakka, Richard, Method and compositions for regulation of 5-alpha reductase activity.
  17. Huang, Jung San; Huang, Shuan Shian, Method of enhancing TGF-β signalling.
  18. Liao, Shutsung; Hiipakka, Richard A., Methods and compositions for regulation of 5-α-reductase activity.
  19. Huang, Shuan Shian; Huang, Jung San, Methods for inhibiting TGF-β.
  20. Ella, Krishna Murthy; Vellimedu, Srinivas Kannappa, Methods for treating a wound using epidermal growth factor formulation.
  21. Kopke, Richard Dana; Floyd, Robert A., Methods for treating acute acoustic trauma.
  22. Detmar, Michael; Kajiya, Kentaro, Methods of reducing skin damage and edema.
  23. Swanzy, James; Lockhart, Leslie, Preservative system.
  24. Swanzy, James; Lockhart, Leslie, Preservative system.
  25. Neirinckx,Rudi D., Treatment of psoriasis through down-regulation of the EGF-receptor with topically-applied EGF.
  26. Nizard, Carine; Moreau, Marielle; Kurfurst, Robin; Friguet, Bertrand; Bulteau, Anne-Laure; Gareil, Monique, Use of Phaeodactylum algae extract for depigmenting the skin.
  27. Detmar, Michael; Kajiya, Kentaro, Use of VEGF-C agonists for inhibiting ultraviolet B-induced skin damage.
  28. Stockfleth, Eggert, Use of a polyphenol for the treatment of a cancerous or pre-cancerous lesion of the skin.
  29. Stockfleth, Eggert, Use of a polyphenol for the treatment of a cancerous or precancerous lesion of the skin.
  30. Hernandez,Steven; Shaffer,Burt, Use of polyphenols to treat skin conditions.
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