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특허 상세정보

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내보내기 페이스북 공유 카카오톡 공유

Immunotherapy of epithelial tumors using intralesional injection of antigens that induce a delayed type hypersensitivity reaction

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61K-039/00    A61K-039/385    A61K-039/295    A61K-039/165    A61K-045/00   
미국특허분류(USC) 424/1841; 424/1931; 424/19611; 424/2011; 424/2121; 424/2741; 424/0852
출원번호 US-0344357 (1999-06-25)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    Foley & Lardner
인용정보 피인용 횟수 : 167  인용 특허 : 2
초록
▼

The present immunotherapy relates to a method of treating epithelial tumors and the pharmaceutical compositions and kits useful in treating such tumors. The immunotherapy comprises injecting an effective amount of a pharmaceutical composition containing at least one antigen into the tumor, wherein the antigen is selected for inducing or having the ability to induce a cutaneous delayed type hypersensitivity (DTH) response in the subject prior to the injection of the antigen into the tumors. This immunotherapy is particularly useful in treating epithelial ...

대표
청구항

1. A method of treating at least one benign epithelial tumor in a subject comprising injecting an effective amount sufficient to cause regression of said tumor of a pharmaceutical composition comprising an antigen selected from the group consisting of mumps, candida, trichophyton and a combination thereof, into at least one of said tumor in said subject, wherein said tumor is caused by a papilloma virus, and wherein said antigen induces or is capable of inducing a cutaneous delayed type hypersensitivity response in said subject.

이 특허에 인용된 특허 (2)

  1. Boyer Ernest W. (Elkhart IN) Charles Robert L. (Elkhart IN). Compositions for the prevention and treatment of viral-induced tumors. USP1997095662903.
  2. Whittle Nigel Richard,GBX ; Carmichael Jeremy Paddon,GBX ; Connor Stephen Edward,GBX ; Thompson Henry Stephen Grammer,GBX ; Wilson Mark Jonathan,GBX. Polypeptides useful as immunotherapeutic agents and methods of polypeptide preparation. USP2000096123948.

이 특허를 인용한 특허 피인용횟수: 167

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