초록 ▼

Polymerized liposome particles which are linked to a targeting agent and may also be linked to a contrast enhancement agent and/or linked to or encapsulating a treatment agent. The targeting imaging enhancement polymerized liposome particles interact with biological targets holding the image enhance

Polymerized liposome particles which are linked to a targeting agent and may also be linked to a contrast enhancement agent and/or linked to or encapsulating a treatment agent. The targeting imaging enhancement polymerized liposome particles interact with biological targets holding the image enhancement agent to specific sites providing in vitro and in vivo study by magnetic resonance, radioactive, x-ray or optical imaging of the expression of molecules in cells and tissues during disease and pathology. Targeting polymerized liposomes may be linked to or encapsulate a treatment agent, such as, proteins, drugs or hormones for directed delivery to specific biological sites for treatment.

대표청구항 ▼

1. A lipid composition comprising a plurality of particles each comprising a lipid sheet containing lipids with at least one hydrophobic tail group that is covalently cross-linked with a hydrophobic tail group of an adjacent lipid, each particle further comprising a targeting agent attached to hydro

1. A lipid composition comprising a plurality of particles each comprising a lipid sheet containing lipids with at least one hydrophobic tail group that is covalently cross-linked with a hydrophobic tail group of an adjacent lipid, each particle further comprising a targeting agent attached to hydrophilic head groups of a portion of lipids in the lipid sheet, each particle further comprising a substance for delivery to a target tissue.