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Method and apparatus for formulating microspheres and microcapsules 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/50
  • A61K-009/14
출원번호 US-0687706 (2000-10-13)
발명자 / 주소
  • Bagavathikanun Chithambara Thanoo
  • James Murtagh
출원인 / 주소
  • Oakwood Laboratories, L.L.C.
대리인 / 주소
    Watts Hoffmann Fisher & Heinke
인용정보 피인용 횟수 : 27  인용 특허 : 26

초록

A process and apparatus for making and formulating microcapsules and microspheres which can easily be maintained aseptic throughout all stages of the production process.

대표청구항 ▼

1. An apparatus for formulating agent containing polymer bodies comprising a process vessel adapted to maintain a suspension of agent containing polymer bodies in a continuous phase, said process vessel coupled to a formulating medium source and adapted to selectively receive formulating medium from

이 특허에 인용된 특허 (26)

  1. Yamada Minoru (Kawanishi JPX) Heya Toshiro (Takarazuka JPX) Ogawa Yasuaki (Otokuni-gun JPX), Biodegradable high-molecular polymers, production and use thereof.
    상세보기
  2. Thanoo Bagavathikanun Chithambara ; Murtagh James, Continuous microsphere process.
    상세보기
  3. Sliwka Wolfgang (Weinheim DEX), Continuous preparation of microcapsules with melamine-formaldehyde condensate walls in aqueous dispersion.
    상세보기
  4. Dahm Manfred (Leverkusen DEX) Jabs Gert (Odenthal DEX) Wawra Georg (Leverkusen DEX), Continuous production of microcapsule dispersions.
    상세보기
  5. Hutchinson Francis G. (Lymm GBX), Continuous release pharmaceutical compositions.
    상세보기
  6. Okada Hiroaki (Osaka JPX) Ogawa Yasuaki (Osaka JPX) Yashiki Takatsuka (Hyogo JPX), Method for producing microcapsule.
    상세보기
  7. Okada Hiroaki (Osaka JPX) Ogawa Yasuaki (Osaka JPX) Yashiki Takatsuka (Hyogo JPX), Method for producing microcapsule.
    상세보기
  8. Yamamoto Masaki (Osaka JPX) Takada Shigeyuki (Suita JPX) Ogawa Yasuaki (Ibaraki ; all JPX), Method for producing microcapsule.
    상세보기
  9. Igari Yasutaka (Kobe JPX) Yamamoto Kazumichi (Nara JPX) Okamoto Kayoko (Osaka JPX) Yamagata Yutaka (Kobe JPX), Method of producing sustained-release preparation.
    상세보기
  10. Kent John S. (Cupertino CA) Lewis Danny H. (Birmingham AL) Sanders Lynda M. (Palo Alto CA) Tice Thomas R. (Birmingham AL), Microencapsulation of water soluble active polypeptides.
    상세보기
  11. Tice Thomas R. (Helena AL) Lewis Danny H. (Gardendale AL), Microencapsulation process.
    상세보기
  12. Tice Thomas R. (Birmingham AL) Gilley Richard M. (Birmingham AL), Microencapsulation process and products therefrom.
    상세보기
  13. Mathiowitz Edith ; Mullon Claudy J.P. ; Domb Abraham J. ; Langer Robert S., Microspheres comprising polymer and drug dispersed there within.
    상세보기
  14. DeLuca Patrick P. (Lexington KY) Kanke Motoko (Fukuyama JPX) Sato Toyomi (Tokyo CA JPX) Schroeder Hans G. (Encinitas CA), Porous microspheres for drug delivery and methods for making same.
    상세보기
  15. Ober Christopher K. (Oakville CAX) Branston Randolph E. (Sarnia CAX), Preparation of ink jet compositions.
    상세보기
  16. Fong, Jones W., Process for preparation of microspheres.
    상세보기
  17. Dirix Cardina A. M. C. (Westervoort NLX) Kamp Hendrikus J. M. (Westervoort NLX) Sam Anthonius P. (Heesch NLX), Process for the preparation of biologically active material containing polymeric microcapsules.
    상세보기
  18. Fessi Curt (Paris FRX) Devissaguet Jean-Philippe (Neuilly S/Seine FRX) Puisieux Francis (Maisons Alfort MO FRX) Thies Curt (St. Louis MO), Process for the preparation of dispersible colloidal systems of a substance in the form of nanoparticles.
    상세보기
  19. Devissaguet Jean-Philippe (Neuilly sur Seine FRX) Fessi Hatem (Paris FRX) Puisieux Francis (Maisons Alfort FRX), Process for the preparaton of dispersible colloidal systems of a substance in the form of nanocapsules.
    상세보기
  20. Maedera Koichi (Suita JPX) Hori Masuhisa (Amagasaki JPX) Futo Tomomichi (Ikeda JPX), Production of microcapsules of water-soluble drugs.
    상세보기
  21. Okada Hiroaki (Osaka JPX) Ogawa Yasuaki (Osaka JPX) Yashiki Takatsuka (Hyogo JPX), Prolonged release microcapsule.
    상세보기
  22. Yamada Minoru (Kawanishi JPX) Ishiguro Seiko (Kawanishi JPX) Ogawa Yasuaki (Otokuni JPX), Prolonged release preparation and polymers thereof.
    상세보기
  23. Yoshida Masaru (Gunma JPX) Asano Masaharu (Gunma JPX) Kaetsu Isao (Gunma JPX) Nakai Katsuyuki (Gunma JPX) Yamanaka Hidetoshi (Gunma JPX) Shida Keizo (Gunma JPX) Shiraishi Akira (Tokyo JPX), Slow-release composite and process for producing the same.
    상세보기
  24. Carr Merle E. (Chillicothe IL) Doane William M. (Morton IL) Wing Robert E. (Peoria IL) Bagley Edward B. (Morton IL), Starch encapsulation of biologically active agents by a continuous process.
    상세보기
  25. Yamamoto Masaki (Osaka JPX) Takada Shigeyuki (Osaka JPX) Ogawa Yasuaki (Osaka JPX), Sustained release microcapsule.
    상세보기
  26. Kamei Shigeru (Takarazuka JPX) Igari Yasutaka (Kobe JPX) Ogawa Yasuaki (Ohyamazaki JPX), Sustained-release preparation.
    상세보기

이 특허를 인용한 특허 (27)

  1. Palmer, Daniel; Shadick, Owen, Apparatus and method for making solid beads.
    상세보기
  2. Ramstack, J. Michael, Apparatus for preparing microparticles using liquid-liquid extraction.
    상세보기
  3. Neumann, Christian, Closed single-use system for mixing, storing and homogenizing liquids in clean or sterile conditions.
    상세보기
  4. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Ye, Qiang; Duron, Sergio G.; Dellamary, Luis A.; Lebel, Carl; Harris, Jeffrey P., Controlled release compositions for modulating free-radical induced damage and methods of use thereof.
    상세보기
  5. Lichter, Jay; Trammel, Andrew M.; Piu, Fabrice; Ye, Qiang; Scaife, Michael Christopher; Vollrath, Benedikt; Duron, Sergio G.; Dellamary, Luis A.; Lebel, Carl; Harris, Jeffrey P., Controlled release compositions for modulating free-radical induced damage and methods of use thereof.
    상세보기
  6. Lichter, Jay; Vollrath, Benedikt; Duron, Sergio G.; Lebel, Carl; Piu, Fabrice; Ye, Qiang; Dellamary, Luis A.; Trammel, Andrew M.; Scaife, Michael Christopher; Harris, Jeffrey P., Controlled-release otic structure modulating and innate immune system modulating compositions and methods for the treatment of otic disorders.
    상세보기
  7. Brown, Larry R.; Bisker-Leib, Vered; Scott, Terrence L.; Lafreniere, Debra; Machen, Jennifer; Giannoukakis, Nick, Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes.
    상세보기
  8. Brown, Larry R.; Bisker-Leib, Vered; Scott, Terrence L.; Lafreniere, Debra; Machen, Jennifer; Giannoukakls, Nick, Delivery of AS-oligonucleotide microspheres to induce dendritic cell tolerance for the treatment of autoimmune type 1 diabetes.
    상세보기
  9. Thanoo, Bagavathikanun C.; Murtagh, James, Gonadotropin releasing hormone antagonists.
    상세보기
  10. Thanoo, Bagavathikanun Chithambara; Smith, Edward Caldwell; Smith, Mark, Manufacture of microspheres using a hydrocyclone.
    상세보기
  11. Huang, Shou-Min; Liu, Chun-Wei; Yang, Kuo-Hua, Method and device for continuously preparing microspheres, and collection unit thereof.
    상세보기
  12. Palmer, Daniel; Shadick, Owen, Method for making solid beads.
    상세보기
  13. Ramstack, J. Michael, Method for preparing microparticles using liquid-liquid extraction.
    상세보기
  14. Brown, Larry; McGeehan, John K.; Rashba-Step, Julia; Scott, Terrence L., Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation.
    상세보기
  15. Darvari, Ramin; Lambert, Adam; Rashba-Step, Julia E.; Yang, Mark X.; Zhang, Junhong; O'Connell, Ed, Methods of processing compositions containing microparticles.
    상세보기
  16. Piran, Uri; Mehr, Eugene; Brown, Larry R.; McGeehan, John K.; O'Connell, Ed, Methods of processing compositions containing microparticles.
    상세보기
  17. Piran, Uri, Methods of processing multi-phasic dispersions.
    상세보기
  18. Brown, Larry R.; Giannoukakis, Nick; Gillis, Kimberly A.; Trucco, Massimo, Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes.
    상세보기
  19. Brown, Larry R.; Scott, Terrence L.; Lafreniere, Debra; Bisker-Leib, Vered, Nucleic acid microspheres, production and delivery thereof.
    상세보기
  20. Scott, Terrence; Lafreniere, Debra; Bisker-Leib, Vered; Brown, Larry, Nucleic acid microspheres, production and delivery thereof.
    상세보기
  21. Brown,Larry R., Production of microspheres.
    상세보기
  22. Brown, Larry; Bisker-Leib, Vered; LaFreniere, Debra; McGeehan, John; Rashba-Step, Julia; Scott, Terrence, Protein microspheres having injectable properties at high concentrations.
    상세보기
  23. Brown, Larry R.; Yang, Mark X.; O'Connell, Ed, Protein microspheres retaining pharmacokinetic and pharmacodynamic properties.
    상세보기
  24. Atkinson, Jeffrey L.; Chambers, Brian Keith, Solvent extraction microencapsulation with tunable extraction rates.
    상세보기
  25. Futo, Tomomichi; Saito, Kazuhiro; Hoshino, Tetsuo; Hori, Masuhisa, Sustained-release composition and method for producing the same.
    상세보기
  26. Futo, Tomomichi; Saito, Kazuhiro; Hoshino, Tetsuo; Hori, Masuhisa, Sustained-release composition and method for producing the same.
    상세보기
  27. Futo, Tomomichi; Saito, Kazuhiro; Hoshino, Tetsuo; Hori, Masuhisa, Sustained-release composition and method for producing the same.
    상세보기

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