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Cleaning compositions containing multiply-substituted protease variants

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C11D-003/00
출원번호 US-0529905 (2000-04-20)
국제출원번호 PCT/US98/22588 (1998-10-23)
§371/§102 date 20000420 (20000420)
국제공개번호 WO99/20727 (1999-04-29)
발명자 / 주소
  • Chanchal Kumar Ghosh
  • AndreCesar Baeck BE
  • Ryohei Ohtani JP
  • Alfred Busch BE
  • Michael Stanford Showell
  • Ayrookaran J. Poulose
  • Volker Schellenberger
  • James T. Kellis, Jr.
  • Christian Paec
인용정보 피인용 횟수 : 46  인용 특허 : 8

초록

The present invention relates to cleaning compositions comprising a protease variant. One cleaning composition comprises a protease variant including a substitution of an amino acid residue with another naturally occurring amino acid residue at an amino acid residue position corresponding to positio

대표청구항

1. A fabric and/or dishwashing and/or hard surface cleaning composition comprising:a) from 0.0001% to 10% by weight, of a protease variant wherein said protease variant includes a substitution of an amino acid residue with another naturally occurring amino acid residue at one or more amino acid resi

이 특허에 인용된 특허 (8)

  1. Estell David A. (San Mateo CA) Wells James A. (Burlingame CA) Bott Richard R. (Burlingame CA), Modified enzymes and methods for making same.
  2. Aaslyng Dorrit,DKX ; Branner Sven,DKX ; Hastrup Sven,DKX ; N.o slashed.rskov-Lauritsen Leif,DKX ; Olsen Ole Hvilsted,DKX ; Simonsen Merete,DKX ; Casteleijn Eric,NLX ; Egmond Maarten Robert,NLX ; Have, Modified subtilisins and detergent compositions containing same.
  3. Estell David A. (Mountain View CA) Bott Richard R. (Burlingame CA) Power Scott D. (San Bruno CA) Wells James A. (San Mateo CA), Non-human carbonyl hydrolase mutants, vectors encoding same and hosts transformed with said vectors.
  4. Baeck Andre (Bonheiden BEX) Ghosh Chanchal Kumar (West Chester OH) Graycar Thomas Paul (Pacifica CA) Bott Richard Ray (Burlingame CA) Wilson Lori Jean (Millbrae CA) Brode Philip Frederick (Cincinnati, Protease-containing cleaning compositions.
  5. Zukowski Mark M. (Thousand Oaks CA) Stabinsky Yitzhak (Boulder CO) Levitt Michael (London GB2), Subtilisin analogs.
  6. Caldwell Robert M. (San Carlos CA) Estell David A. (San Mateo CA) Graycar Thomas P. (Pacifica CA), Subtilisin mutants.
  7. Caldwell Robert M. (San Carlos) Estell David A. (San Mateo) Graycar Thomas P. (Pacifica CA), Subtilisin mutants.
  8. Estell David A. (San Mateo CA) Caldwell Robert M. (San Francisco CA) Bott Richard R. (Burlingame CA) Graycar Thomas P. (Pacifica CA), Subtilisins modified at position 225 resulting in a shift in catalytic activity.

이 특허를 인용한 특허 (46)

  1. Homan, Jane; Imboden, Michael; Riggs, Michael; Carryn, Stephane; Schaefer, Deborah A., Biocides.
  2. Aehle, Wolfgang; Estell, David A.; Hommes, Ronaldus W. J.; Jones, Brian E.; Kolkman, Marc; Leeflang, Chris; Oh, Hiroshi; Poulose, Ayrookaran J.; Shaw, Andrew; van der Kley, Wilhelmus A. H.; van Marrewijk, Leonardus P. M., Cellulomonas 69B4 serine protease variants.
  3. Basler, Joshua R; Cascão-Pereira, Luis G; Estell, David A; Kellis, Jr., James T; Pisarchik, Alexander; Poulose, Ayrookaran J.; Torres Pazmino, Daniel E., Compositions and methods comprising protease variants.
  4. Aehle, Wolfgang; Cascao-Pereira, Luis G.; Estell, David A.; Goedegebuur, Frits; Kellis, Jr., James T.; Poulose, Ayrookaran J.; Schmidt, Brian F., Compositions and methods comprising serine protease variants.
  5. Amin, Neelam S.; Augustyn, Katherine; Basler, Joshua R.; Cascao-Pereira, Luis G.; Collier, Katherine D.; Concar, Edward M.; Estell, David A.; Kellis, Jr., James T.; Magennis, Euan John; Pisarchik, Alexander; Poulose, Ayrookaran J.; Souter, Philip Frank; Ward, Glenn Steven; Yao, Jian, Compositions and methods comprising serine protease variants.
  6. Jones, Brian E.; Kolkman, Marc; Qian, Zhen; Laursen, Brian Sogaard; Kragh, Karsten M.; Pricelius, Sina; Yu, Zheyong; Babe, Lilia Maria; Estabrook, Melodie, Detergent compositions containing Bacillus agaradhaerens mannanase and methods of use thereof.
  7. Jones, Brian E.; Kolkman, Marc; Qian, Zhen; Laursen, Brian Sogaard; Kragh, Karsten M.; Pricelius, Sina; Yu, Zheyong; Babe, Lilia Maria; Estabrook, Melodie, Detergent compositions containing Bacillus agaradhaerens mannanase and methods of use thereof.
  8. Adams, Christian; Schmidt, Brian, Detergent compositions containing Geobacillus stearothermophilus lipase and methods of use thereof.
  9. Nesbitt, Bruce, Electrosurgical electrode and method of manufacturing same.
  10. Nesbitt, Bruce, Electrosurgical electrode and method of manufacturing same.
  11. Nesbitt, Bruce, Electrosurgical electrode and method of manufacturing same.
  12. Fiore,Robert A.; Huang,Samuel J., Foaming cleansing preparation and system comprising coated acid and base particles.
  13. Wittorff, Helle; Neergaard, Jesper, Method of cleaning a surface attached with at least one chewing gum lump.
  14. Basler, Joshua Roy; Cascao-Pereira, Luis Gustavo; Estell, David A.; Kellis, Jr., James T.; Pisarchik, Alexander; Poulose, Ayrookaran J.; Torres-Pazmino, Daniel, Methods for cleaning using a variant protease derived from subtilisin.
  15. Cascao-Pereira, Luis G.; Estell, David A.; Kellis, James T.; Poulose, Ayrookaran J., Methods for improving multiple protein properties.
  16. Jones, Brian E.; Kolkman, Marc; Leeflang, Chris, Methods of cleaning using a .
  17. Jones, Brian E.; Kolkman, Marc; Leeflang, Chris; Oh, Hiroshi; Poulose, Ayrookaran J.; Sadlowski, Eugene S.; Shaw, Andrew; van Marrewijk, Leo; Van Der Kleij, Wilhelmus A. H., Micrococcineae serine protease polypeptides and compositions thereof.
  18. Ferrari, Eugenio; Estell, David A., Modified protease propeptides.
  19. Ferrari, Eugenio; Estell, David A., Modified proteases.
  20. Van Kimmenade, Anita; Fioresi, Carol; Peres, Caroline; Ferrari, Eugenio, Modified secretion system to increase expression of polypeptides in bacteria.
  21. Van Kimmenade, Anita; Fioresi, Carol; Peres, Caroline; Ferrari, Eugenio, Modified secretion system to increase expression of polypeptides in bacteria.
  22. Aehle, Wolfgang; Estell, David A.; Hommes, Ronaldus W. J.; Jones, Brian E.; Kolkman, Marc; Leeflang, Chris; Oh, Hiroshi; Poulose, Ayrookaran J.; Shaw, Andrew; Van der Kley, Wilhelmus A. H.; Van Marrewijk, Leonardus P. M., Multiple mutation variants of serine protease.
  23. Aehle, Wolfgang; Estell, David A.; Hommes, Ronaldus W. J.; Jones, Brian E.; Kolkman, Marc; Leeflang, Chris; Oh, Hiroshi; Poulose, Ayrookaran J.; Shaw, Andrew; van der Kley, Wilhelmus A. H.; van Marrewijk, Leonardus P. M., Multiple mutation variants of serine protease.
  24. Poulose,Ayrookaran J.; Estell,David A; Kellis, Jr.,James T; Bott,Richard R., Multiply-substituted protease variants.
  25. Cascao-Pereira, Luis G.; Estell, David A.; Kellis, Jr., James T., Protease comprising one or more combinable mutations.
  26. Ferrari, Eugenio; Fioresi, Carol; van Kimmenade, Anita, Proteases with modified pro regions.
  27. Ferrari, Eugenio; Fioresi, Carol; van Kimmenade, Anita, Proteases with modified pro regions.
  28. Ferrari, Eugenio; Fioresi, Carol; van Kimmenade, Anita, Proteases with modified pro regions.
  29. Minning, Stefan; Knotzel, Jurgen Carsten Franz; Sorensen, Niels Henrik, Savinase variants having an improved wash performance on egg stains.
  30. Minning, Stefan; Knotzel, Jurgen Carsten Franz; Sorensen, Niels Henrik, Savinase variants having an improved wash performance on egg stains.
  31. Jones, Brian E.; Kolkman, Marc; Leeflang, Chris, Streptomyces protease.
  32. Draborg, Henriette; Hansen, Peter Kamp; Bjornvad, Mads Eskelund; Norregaard-Madsen, Mads; Mikkelsen, Mikael, Subtilase variants.
  33. Draborg, Henriette; Hansen, Peter Kamp; Bjornvad, Mads Eskelund; Norregaard-Madsen, Mads; Mikkelsen, Mikael, Subtilase variants.
  34. Draborg, Henriette; Nielsen, Vibeke Skovgaard; Minning, Stefan, Subtilase variants.
  35. Fano, Tina Sejersgard; Von Der Osten, Claus; Kruger, Malene Kappen; Norregaard-Madsen, Mads, Subtilase variants.
  36. Fano, Tina Sejersgard; Von Der Osten, Claus; Kruger, Malene Kappen; Norregaard-Madsen, Mads, Subtilase variants.
  37. Svendsen, Allan; Draborg, Henriette, Subtilase variants and compositions comprising the same.
  38. Minning, Stefan; Draborg, Henriette; Roggen, Erwing Ludo; Soni, Nanna Kristensen; Berg, Ninna Willestofte; Lyngstrand, Stina Thulesen, Subtilase variants having altered immunogenicity.
  39. Minning, Stefan; Draborg, Henriette; Roggen, Erwing Ludo; Soni, Nanna Kristensen; Berg, Ninna Willestofte; Lyngstrand, Stina Thulesen, Subtilase variants having altered lmmunogenicity.
  40. Svendsen, Allan; Draborg, Henriette, Subtilases.
  41. Svendsen, Allan; Draborg, Henriette, Subtilases.
  42. Estell, David A.; Aehle, Wolfgang, Systematic evaluation of sequence and activity relationships using site evaluation libraries for engineering multiple properties.
  43. Imboden, Michael; Riggs, Michael Warren; Schaefer, Deborah A.; Homan, Jane, Targeted cryptosporidium biocides.
  44. Imboden, Michael; Riggs, Michael; Schaefer, Deborah A.; Homan, Jane; Bremel, Robert D., Targeted cryptosporidium biocides.
  45. Estell, David A.; Hommes, Ronaldus W. J.; Liu, Amy D.; Shaw, Andrew, Thermolysin variants.
  46. Estell, David A.; Hommes, Ronaldus W. J.; Liu, Amy D.; Shaw, Andrew, Thermolysin variants and detergent compositions therewith.
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