초록 ▼

A composite paramagnetic particle and method of making are provided. In one aspect of the invention, a particle comprising a multitude of submicron polymer bead aggregates covalently cross-linked to each other to form larger diameter particles is presented. Distributed throughout the composite param

A composite paramagnetic particle and method of making are provided. In one aspect of the invention, a particle comprising a multitude of submicron polymer bead aggregates covalently cross-linked to each other to form larger diameter particles is presented. Distributed throughout the composite paramagnetic particle are vacuous cavities. Each submicron polymer bead has distributed throughout its interior and surface submicron magnetite crystals. In another aspect of the invention, composite particles are made using high energy ultrasound during polymerization of one or more vinyl monomers. In one embodiment, high energy ultrasound is used during an emulsification step and during the early stages of the polymerization process to produce micron sized composite paramagnetic particles. The particles according to the invention exhibit a high percent magnetite incorporation and water and organic solvent stability.

대표청구항 ▼

1. A paramagnetic particle comprising:a plurality of interconnected bead aggregates separated by vacuous cavities, wherein a portion of said bead aggregates are covalently interconnected; each said bead aggregate comprises two or more primary beads attached to each other and at least two of said two

1. A paramagnetic particle comprising:a plurality of interconnected bead aggregates separated by vacuous cavities, wherein a portion of said bead aggregates are covalently interconnected; each said bead aggregate comprises two or more primary beads attached to each other and at least two of said two or more primary beads are covalently attached to each other; each said primary bead comprising a polymer of at least one vinyl monomer; a plurality of magnetite crystals dispersed within said primary beads, on the surface of said primary beads and between said primary beads.