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Pharmaceutical agents for the treatment of emesis 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/445
  • A61K-031/165
  • C07F-213/00
  • C07F-009/80
출원번호 US-0529891 (1995-09-18)
발명자 / 주소
  • Harry A. Watson, Jr.
  • William M. Snyder
  • Glenn E. Wilcox
출원인 / 주소
  • Pfizer INC
대리인 / 주소
    Peter C. Richardson
인용정보 피인용 횟수 : 11  인용 특허 : 38

초록 ▼

The present invention relates to a novel process for preparing and resolving 3-amino-2-phenylpiperidine and for synthesizing from the enantiomers of such compound certain pharmaceutically active substituted 2-phenyl-3-benzylaminopiperidines. The substituted 2-phenyl-3-benzylaminopiperidines that can

대표청구항

1. A method of treating or preventing emesis in a mammal, comprising administering to said mammal an amount of a compound that is a substance P receptor antagonist, or a pharmaceutically acceptable salt thereof, that is effective in treating or preventing emesis.

이 특허에 인용된 특허 (38)

  1. Desai Manoj C. (Mystic CT) Rosen Terry J. (East Lyme CT), 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use.
    상세보기
  2. Chez Ephriam (21 Braeside Terrace Sherwood Park ; Alberta CAX T8A 3V6), Apparatus and method for electronic decomposition of water into aqueous free radicals and free electrons.
    상세보기
  3. Moeglich ; Karl, Apparatus for removal of contaminants from water.
    상세보기
  4. Caldwell ; Donald L. ; Fuchs ; Jr. ; Raymond J., Catalytic decomposition of hypochlorite.
    상세보기
  5. Bon Charles K. (Concord CA) Knowles Vera M. (Martinez CA), Catalytic decomposition of sodium hypochlorite in highly alkaline solutions.
    상세보기
  6. Lichtin Norman N. (Newton Center MA) DiMauro Thomas M. (New York NY) Svrluga Richard C. (Brookline MA), Catalytic process for degradation of organic materials in aqueous and organic fluids to produce environmentally compatib.
    상세보기
  7. Krause William A. (Houston TX) Langeland Leonard E. (Houston TX), Compact electrocatalytic sewage treatment unit for maritime use.
    상세보기
  8. Wang Lawrence K. (Latham NY) Kurylko Lubomry (New Providence NJ) Wang Mu H. S. (Latham NY), Contamination removal system employing filtration and plural ultraviolet and chemical treatment steps and treatment mode.
    상세보기
  9. Kirch Rudolf (Immenstaad DEX), Decontamination of waste water.
    상세보기
  10. Bryan Stephen J. (High Shincliffe GB2) Twigg Martyn V. (Yarm GB2), Effluent treatment.
    상세보기
  11. Weres Oleh (P.O. Box 116 Vineburg CA 95487) Hoffmann Michael R. (1625 Laurel St. South Pasadena CA 91030), Electrochemical method and device for generating hydroxyl free radicals and oxidizing chemical substances dissolved in w.
    상세보기
  12. Gram Helen F. (Los Alamos NM) Muller Martin E. (Los Alamos NM) Pendergrass Ann M. (Los Alamos NM) Rink Philip A. (Everett WA), Electrolytic method and cell for sterilizing water.
    상세보기
  13. Kim Bang M. (Schenectady NY) Weininger Joseph L. (Schenectady NY), Electrolytic reactor for cleaning wastewater.
    상세보기
  14. Hagan Russell M. (Ware GB3) Bunce Keith T. (Research Triangle Park NC), Medical use for tachykinin antagonists.
    상세보기
  15. Hayden Richard A. (Pittsburgh PA), Method for SOx removal by catalytic carbon.
    상세보기
  16. Pisani Joseph (Sierra Madre CA), Method for removing oxidizable contaminants in cooling water used in conjunction with a cooling tower.
    상세보기
  17. Fochtman Edward G. (Elmhurst IL) Koch Roger L. (Miami FL) Forbes Forrest S. (Lancaster CA), Method for treating contaminated wastewater.
    상세보기
  18. Crawford Roger A. (Wadsworth OH) Simmons Robert B. (Norton OH), Method of decomposing hypochlorite ion in a basic solution.
    상세보기
  19. Kerridge John R. (Arnos Grove London N.11 GB2), Method of removing contaminating impurities from leisure pool water.
    상세보기
  20. McPhee Wayne (Toronto CAX) Martin Paul (Willowdale CAX), Methods of catalytic photooxidation.
    상세보기
  21. Hartkorn Karl H. (Heinrich-Zille. Strasse 37 6085 Nauheim DEX), Oxidation and adsorption method for removing contaminating substances from liquids.
    상세보기
  22. Habermann Wolfgang (Mainz DEX) Hammes Peter (Ruppertsberg DEX) Engelhardt Hubert (Ludwigshafen DEX) Geiger Wolfgang (Plankstadt DEX) Haltrich Walter (Edingen-Neckarhausen DEX) Simmler Werner (Ludwigs, Oxidative treatment of wastewaters.
    상세보기
  23. Ciambrone David Fred (Santee CA), Ozone oxidation of waste water.
    상세보기
  24. Gerlach, Klaus; Lange, Wolfgang; Loh, Dieter, Process and an apparatus for enriching liquids with oxygen.
    상세보기
  25. Moeglich ; Karl, Process and apparatus for removal of contaminants from water.
    상세보기
  26. Kaczur Jerry J. (Cleveland TN) Cawlfield David W. (Cleveland TN) Woodard Kenneth E. (Cleveland TN), Process and apparatus for the removal of oxyhalide species from aqueous solutions.
    상세보기
  27. Diehl Manfred (Frankfurt) Fischer Joachim (Rodenbach) Wolf Hubert (Hammersbach DEX), Process for the detoxification of aqueous solutions containing cyanohydrins and/or nitriles.
    상세보기
  28. Steiner Norbert (Albstadt DEX) Gos Stephen (Hanau DEX) Ladwig Frank (Gruendau DEX) Diehl Manfred (Frankfurt DEX), Process for the detoxification of cyanide-containing aqueous solutions.
    상세보기
  29. Swallow Kathleen C. (West Newbury MA) Killilea William R. (West Chelmsford MA) Hong Glenn T. (Tewksbury MA) Bourhis Alain L. (Framingham MA), Process for the oxidation of materials in water at supercritical temperatures utilizing reaction rate enhancers.
    상세보기
  30. Kaczur Jerry J. (Cleveland TN) Cawlfield David W. (Cleveland TN) Woodard ; Jr. Kenneth E. (Cleveland TN), Process for the removal of oxynitrogen species for aqueous solutions.
    상세보기
  31. Clough Thomas J. (Santa Monica CA), Process for treating contaminants in aqueous-based materials.
    상세보기
  32. Cook Brian G. (St. Catharines CAX), Process for treatment of water and apparatus therefor.
    상세보기
  33. Yang Xinyu (23 Laoyang Zhuang Chengbei ; Zaoqiang County ; Hebei 053100 CNX), Process of removing cyanide from waste water.
    상세보기
  34. Krause William A. (Houston TX) Shea Evan P. (Kansas City MO), System for electrocatalytic treatment of waste water streams.
    상세보기
  35. Kreusch Edward G. (Arlington Heights IL) Brodzik Bruce F. (Mundelein IL), System for removing iron and/or other chemically reducing substances from potable water.
    상세보기
  36. Christensen Wendell N. (Brigham City UT) Poulter Larry W. (Ogden UT), Treatment of water containing cyanide.
    상세보기
  37. Dietrich Jospeh J. (Painesville OH), Wastewater treatment.
    상세보기
  38. Torrado Santiago D. (Maldonado ; 48 Madrid ESX 28006), Water treatment unit.
    상세보기

이 특허를 인용한 특허 (11)

  1. Jimenez, Juan-Miguel; Bemis, Guy; Maltais, Francois; Wang, Tiansheng; Knegtel, Ronald; Davis, Chris; Fraysse, Damien; Boyall, Dean; Settimo, Luca; Young, Stephen; Mortimore, Michael, Amino substituted pyridines as potent kinase inhibitors.
    상세보기
  2. Maltais, Francois; Bemis, Guy W.; Wang, Tiansheng; Jimenez, Juan-Miguel; Settimo, Luca; Young, Stephen; Boyall, Dean; Fraysse, Damien; Davis, Christopher John, Aminopyridine kinase inhibitors.
    상세보기
  3. Maltais, Francois; Bemis, Guy W.; Wang, Tiansheng; Jimenez, Juan-Miguel; Settimo, Luca; Young, Stephen; Boyall, Dean; Fraysse, Damien; Davis, Christopher John, Aminopyridine kinase inhibitors.
    상세보기
  4. Jimenez, Juan-Miguel; Bemis, Guy William; Maltais, Francois; Wang, Tiansheng; Knegtel, Ronald Marcellus Alphonsus; Davis, Christopher John; Fraysse, Damien; Boyall, Dean; Settimo, Luca; Young, Stephen; Mortimore, Michael Paul, Kinase inhibitors.
    상세보기
  5. Jimenez, Juan-Miguel; Settimo, Luca; Fraysse, Damien; Brenchley, Guy; Davis, Christopher John; Miller, Andrew W., Pyrazolopyrazine kinase inhibitors.
    상세보기
  6. Boyall, Dean; Brenchley, Guy; Davis, Chris; Fraysse, Damien; Golec, Julian; Jimenez, Juan-Miguel; Miller, Andrew; Settimo, Luca; Twin, Heather; Young, Stephen, Pyrazolopyridine kinase inhibitors.
    상세보기
  7. Boyall, Dean; Brenchley, Guy; Fraysse, Damien; Jimenez, Juan-Miguel; Settimo, Luca, Pyrazolopyridine kinase inhibitors.
    상세보기
  8. Jimenez, Juan-Miguel; Collier, Philip, Pyrazolopyridines.
    상세보기
  9. Jimenez, Juan-Miguel; Settimo, Luca; Fraysse, Damien; Brenchley, Guy; Davis, Christopher John; Miller, Andrew W., Pyrazolopyrimidine kinase inhibitors.
    상세보기
  10. Brenchley, Guy; Boyall, Dean; Fraysse, Damien; Jimenez, Juan-Miguel; Settimo, Luca, Tri-cyclic pyrazolopyridine kinase inhibitors.
    상세보기
  11. Jimenez, Juan-Miguel; Studley, John; Knegtel, Ronald; Settimo, Luca; Davis, Christopher John; Fraysse, Damien; Collier, Philip N.; Brenchley, Guy; Boyall, Dean; Miller, Andrew; Twin, Heather; Young, Stephen, Tri-cyclic pyrazolopyridine kinase inhibitors.
    상세보기

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