초록

Disclosed herein are bioadhesive medical devices formed in whole or in part of a cohesive bioadhesive copolymer of a carboxyl functional monomer and a hydrophobic functional monomer.

대표청구항 ▼

1. A method of forming a medical device with a bioadhesive surface comprising:copolymerizing at least a first carboxyl functional moiety-bearing monomer with at least a first hydrophobic moiety-bearing monomer to form a bioadhesive copolymer, said first hydrophobic moiety-bearing monomer being selec

1. A method of forming a medical device with a bioadhesive surface comprising:copolymerizing at least a first carboxyl functional moiety-bearing monomer with at least a first hydrophobic moiety-bearing monomer to form a bioadhesive copolymer, said first hydrophobic moiety-bearing monomer being selected from the group consisting of: [EQU6]Z=-H, -CH3, or -CH2CH3 Y=nothing or O Ar=C1-C3 alkyl substituted aromatic ring or unsubstituted aromatic ring n=1-5 orR1=C1-C5 alkyl substituted aromatic ring or unsubstituted aromatic ring R2=hydrogen or C1-C5 alkyl group Z=-H, -CH3, or -CH2CH3 Y=nothing or O Ar=C1-C3 alkyl substituted aromatic ring or unsubstituted aromatic ring n=1-5 R1=C1-C5 alkyl substituted aromatic ring or unsubstituted aromatic ring R2=hydrogen or C1-C5 alkyl group wherein said copolymer has a tensile strength of at least about 10 psi; andproviding the bioadhesive copolymer as a surface for a medical device, such that the surface remains exposed for adhesion to a tissue.