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Kafe 바로가기국가/구분 | United States(US) Patent 등록 |
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국제특허분류(IPC7판) |
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출원번호 | US-0417080 (1999-10-13) |
발명자 / 주소 |
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출원인 / 주소 |
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대리인 / 주소 |
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인용정보 | 피인용 횟수 : 567 인용 특허 : 6 |
A method is disclosed for treating patients suffering from heart failure to increase cardiac output. The patient's vagus nerve is electrically stimulated or modulated with a sequence of substantially equally spaced pulses by an implanted neurostimulator, and the frequency of the stimulating pulses i
A method is disclosed for treating patients suffering from heart failure to increase cardiac output. The patient's vagus nerve is electrically stimulated or modulated with a sequence of substantially equally spaced pulses by an implanted neurostimulator, and the frequency of the stimulating pulses is adjusted until the patient's heart rate reaches a target rate within a relatively stable target rate range below the low end of the patient's customary resting heart rate. The frequency of the stimulating pulses is maintained at the frequency which ultimately produced the relatively stable target rate range so as not to deviate markedly from the target rate, at least so long as the patient remains at rest. An activity sensor associated with the implanted neurostimulator detects physical activity of the patient and adjusts the frequency of the stimulating pulses accordingly, to elevate the heart rate during periods of physical activity by the patient. When the patient ceases the activity, the vagal stimulation reverts along a prescribed fall-back path to a frequency that will reproduce the target heart rate.
1. A method of treating patients suffering from heart failure, which comprises the steps of:stimulating the patient's vagus nerve with electrical pulses generated at a predetermined repetition frequency to reduce the patient's heart rate toward a target rate range below the lowest heart rate of the
1. A method of treating patients suffering from heart failure, which comprises the steps of:stimulating the patient's vagus nerve with electrical pulses generated at a predetermined repetition frequency to reduce the patient's heart rate toward a target rate range below the lowest heart rate of the patient while at rest; and keeping the stimulation frequency at a set value when the patient's heart stabilizes at said target rate, to maintain the heart rate within said target rate range.
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