초록 ▼

The invention provides a composition suitable for topical application comprising: an effective amount of a prostaglandin, a polymer thickener, a lipophilic component, and a buffer system. In another embodiment, the invention provides a composition suitable for topical application comprising: an effe

The invention provides a composition suitable for topical application comprising: an effective amount of a prostaglandin, a polymer thickener, a lipophilic component, and a buffer system. In another embodiment, the invention provides a composition suitable for topical application comprising: an effective amount of a vasoactive agent, a polymer thickener, a lipophilic component, and a buffer system. The invention also provides methods of ameliorating female sexual dysfunction. Also provided are methods of increasing female sexual arousal and methods of enhancing female sexual response.

대표청구항 ▼

1. A method for ameliorating female sexual arousal disorder, comprising the step of administering a composition to the genitalia of a human female in need of treatment, the composition comprising: an amount of a vasoactive agent chosen from the group consisting of prostaglandin E1, pharmaceutically

1. A method for ameliorating female sexual arousal disorder, comprising the step of administering a composition to the genitalia of a human female in need of treatment, the composition comprising: an amount of a vasoactive agent chosen from the group consisting of prostaglandin E1, pharmaceutically acceptable prostaglandin E1 salts, prostaglandin E1 alkyl esters, and mixutres thereof effective to produce an increase in sexual arousal, a polymer thickener, a lipophilic component, a penetration enhancer chosen from the group consisting of alkyl-2-(N,N-disubstituted amino) alkanoates, (N,N-disubstituted amino) alkanol alkanoates and mixtures thereof and a buffer system wherein the pH of the composition is about 3.0 to about 6.0, wherein treatment increases subjective sexual arousal thereby alleviating symptoms of female sexual arousal disorder, wherein female sexual disorder is the persistant or recurrent inability to attain, or to maintain, sufficient sexual excitment, which causes personal distress.