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Methods and compositions for aiding in smoking cessation and for treating pain and other disorders using optically pure (+)-bupropion 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A01N-033/02
  • A61K-031/135
출원번호 US-0803956 (2001-03-13)
발명자 / 주소
  • John R. McCullough
  • Paul D. Rubin
출원인 / 주소
  • Sepracor Inc.
대리인 / 주소
    Pennie & Edmonds LLP
인용정보 피인용 횟수 : 4  인용 특허 : 36

초록

Methods and compositions are disclosed utilizing the optically pure (+)-isomer of bupropion to assist in smoking cessation, for treating smoking and nicotine addiction, and for treating pain, including, but not limited to, chronic pain, neuropathetic pain and reflex sympathetic dystrophy, and other

대표청구항

1. A method of treating pain in a human, which comprises administering to a human in need of treatment for said pain, a therapeutically effective amount of (+)-bupropion or a pharmaceutically acceptable salt thereof, substantially free of its (-)-stereoisomer wherein the amount of (+)-bupropion or a

이 특허에 인용된 특허 (36)

  1. Scharver Jeffrey D. (Durham NC), 3H Labeled compounds.
  2. Kashman Yoel (Tel Aviv ILX) Hirsch Shulamit (Tel Aviv FL ILX) Cross Sue S. (Ft. Pierce FL) Koehn Frank (Vero Beach FL), Antiviral compositions derived from marine sponge epipolasis reiswigi and their methods of use.
  3. Peck Anthony W. (Bromley GB2), Benzodiazepine tranquilizer combinations and the use thereof.
  4. Peck Anthony W. (Bromley GB2), Bupropion and ethanol.
  5. Findlay John W. A. (Chapel Hill NC) Butz Robert F. (Durham NC) Welch Richard M. (Raleigh NC), Bupropion radioimmunoassay, and kit.
  6. Dante Lee G. (Merion Station PA), Composition and method of treating depression using natoxone or naltrexone in combination with a serotonin reuptake inhi.
  7. Findlay John W. A. (Chapel Hill NC) Butz Robert F. (Durham NC) Welch Richard M. (Raleigh NC), Compounds and methods of making.
  8. Mehta Nariman B. (Raleigh NC), Compounds and methods of making same.
  9. Phillips Arthur P. (Raleigh NC), Compounds and methods of making them.
  10. Ludwig Jennie Sue G. (Greenville NC) Bass ; Jr. William L. (Farmville NC) Sutton ; Jr. Joel E. (Greenville NC), Controlled sustained release tablets containing bupropion.
  11. Roberts Eugene (Monrovia CA), Dehydroepiandrosterone therapy for ameleoration of prostate hypertrophy and sexual dysfunction.
  12. Baker Richard W. (Mountain View CA) Smith Kelly L. (Bend OR) Brooke James W. (Sisters OR), Delivery system.
  13. Seibyl John P. (Branford CT) Krystal John H. (New Haven CT) Charney Dennis S. (Hamden CT), Dopamine and noradrenergic reuptake inhibitors in treatment of schizophrenia.
  14. Berger Stephen P. (1 Ewing Ct. Bethesda MD 20817), Dopamine uptake inhibitors in reducing substance abuse and/or craving.
  15. Peck Anthony W. (Bromley GB2), Lorazepam and bupropion, compositions and methods.
  16. Coffman Jeffrey A. (Iowa City IA) Barfknecht Charles F. (Iowa City IA), Magnetic resonance (MR) image enhancement compounds for specific areas of the brain.
  17. Seed John C. (763 Kingston Rd. Princeton NJ 08540), Method of assisting weight loss.
  18. Dackis Charles A. (96 Joan Dr. Watchung NJ 07060) Gold Mark S. (145 Forest Dr. Short Hills NJ 07078), Method of treating psychostimulant addiction.
  19. Young James W., Methods for treating obesity and weight gain using optically pure (-)-bupropion.
  20. Brown Herbert C. (West Lafayette IN), Novel process of producing phenyl or substituted phenylalkylamine pharmaceutical agents and novel chiral intermediates o.
  21. Metcalf Brian Walter (Strasbourg FR) Jung Michel (Illkirch FR), Olefinic derivatives of amino acids.
  22. Theeuwes Felix (Los Altos CA) Ayer Atul D. (Belmont CA), Osmotic system having laminar arrangement for programming delivery of active agent.
  23. Ruff Michael D. (Greenville NC) Kalidindi Sanyasi R. (Edison NJ) Sutton ; Jr. Joel E. (Greenville NC), Pharmaceutical composition containing bupropion hydrochloride and a stabilizer.
  24. Baker Richard W. (Mountain View CA) Brooke James W. (Sisters OR), Pharmaceutical delivery system.
  25. Baker Richard W. (Palo Alto CA) Brooke James W. (Sisters OR), Pharmaceutical delivery system.
  26. Morgan Phillip Frederick ; Musso David Lee ; Partridge John Joseph, Pharmaceutically active morpholinol.
  27. Stern Warren C. (Raleigh NC), Prolactin suppression in mammals.
  28. Findlay John W. A. (Chapel Hill NC) Butz Robert F. (Durham NC) Welch Richard M. (Raleigh NC), Radioactive nuclide labeled propiophenone compounds.
  29. Stern Warren C. (Raleigh NC), Reduction of cholesterol with meta-chloro a 상세보기
  • Ruff Michael D. (Greenville NC) Kalidindi Sanvasi R. (Edison NJ) Sutton ; Jr. Joel E. (Greenville NC), Stabilized Pharmaceutical.
  • Ruff Michael D. ; Kalidindi Sanvasi R. ; Sutton ; Jr. Joel Elmore, Stabilized pharmaceutical.
  • Ruff Michael David ; Kalidindi Sanyasi Raju ; Sutton ; Jr. Joel Elmore, Stabilized pharmaceutical composition containing bupropion.
  • Pinsker Walter, Treatment of migraine headaches and formulations.
  • Stern Warren C. (Raleigh NC), Treatment of minimal brain dysfunction (MBD).
  • Stern Warren C. (Raleigh NC), Treatment of psychosexual dysfunctions.
  • Stern Warren C. (Raleigh NC), Treatment of tardive dyskinesia in mammals.
  • 이 특허를 인용한 특허 (4)

    1. Oberegger, Werner; Eradiri, Okponanabofa; Zhou, Fang; Maes, Paul, Modified release tablet of bupropion hydrochloride.
    2. Jiang, Faming; Khroyan, Taline; Olsen, Cris M.; Polgar, Willma E.; Toll, Lawrence R.; Zaveri, Nurulain T., Nicotinic acetylcholine receptor modulators.
    3. Zaveri, Nurulain T.; Jiang, Faming, Nicotinic acetylcholine receptor modulators.
    4. Zaveri, Nurulain; Jiang, Faming, Nicotinic acetylcholine receptor modulators.
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