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Instruments and methods for performing non-invasive measurements of analyte concentrations and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.

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Instruments and methods for performing non-invasive measurements of analyte concentrations and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels. by disengaging said pins from said process cartridge; (c) a developing roller dismounting step of dismounting said d

Instruments and methods for performing non-invasive measurements of analyte concentrations and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels. by disengaging said pins from said process cartridge; (c) a developing roller dismounting step of dismounting said developing roller from said toner developing container separated by said container separating step; (d) a developing blade dismounting step of dismounting said developing blade from said toner developing container separated by said container separating step; (e) a sealing material filling step of filling a sealing material into a gap formed in a or said toner developing container extending along a longitudinally inside of an end seal provided at each of longitudinally opposite ends thereof; (f) a toner refilling step of refilling the toner into said toner accommodating portion through said toner supply opening; (g) a developing blade mounting step of mounting a or said developing blade on said toner developer container having the sealing material; (h) a developing roller mounting step of mounting a or said developing roller on said toner developer container having the sealing material; and (i) a container coupling step of coupling said toner developing container having said sealing material, said developing blade and said developing roller with a or said cleaning container by engaging pins or said pins into them, whereby said process cartridge can be remanufactured without remounting a toner seal to seal the toner supply opening having been unsealed upon start of use of said process cartridge. 3. A method according to claim 1 or 2, wherein in said sealing material filling step the sealing material is injected to a middle portion of a length of the gap, and then is expanded towards ends of the length. 4. A method according to claim 1 or 2, wherein said sealing material is a plastically deformable sealing material. 5. A method according to claim 4, wherein said sealing material is a high polymer material having a curing property or a thermoplastic high polymer material. 6. A method according to claim 5, wherein said sealing material is silicone bond or hot melt plastic material. 7. A method according to claim 1, wherein said toner refilling step is carried out after said sealing material filling step, said developing blade mounting step and said developing roller mounting step, and wherein said toner refilling step is effected through the toner filling opening. 8. A method according to claim 1 or 2, wherein in said developing blade mounting step, a new blade or a used blade is used. 9. A method according to claim 1 or 2, wherein in said developing roller mounting step, a new roller or a used roller is used. 10. A method according to claim 1 or 2, wherein said electrophotographic photosensitive drum and a cleaning blade are removed from the cleaning container, and the toner contained in said cleaning container and having been removed from said electrophotographic photosensitive drum is removed, before said container coupling step. 11. A method according to claim 10, wherein after the toner is removed, a new or used electrophotographic photosensitive drum and a new or used cleaning blade is mounted. 12. A method according to any one of claim 1 or 2, wherein said process cartridge comprises a gear fixed co-axially with said electrophotographic photosensitive drum and a gear fixed co-axially with said developing roller, which gears are in meshing engagement, and wherein after said container coupling process, said toner developing container and said cleaning container are rotated about said pins to disengage said gears from each other or to make a back clearance of the meshing engagement larger than that during an image forming operation, and the disengagement or larger back clearance is maintained. 13. A method according to claim 12, wherein said toner developing container and said cleaning container are rotated toward each other about said pins at a portion across said pins from said electrophotographic photosensitive drum, and a tape is stuck on said toner developing container and said cleaning container to maintain the disengagement or the larger back clearance. is processed so as to be decentered with respect to an axis of rotational symmetry of a refractive lens, and when a diffraction efficiency of a diffracted light with an order used for optical fiber coupling out of diffracted lights from the diffraction lens is η, the following formula is satisfied: 25%≤η≤40%. 7. The coupling lens according to claim 1 or 2, wherein when a diffraction efficiency of a diffracted light with an order used for optical fiber coupling out of diffracted lights from the diffraction lens is η, the following formula is satisfied: 25%≤η≤40%. 8. The coupling lens according to claim 1, 2, or 6, wherein when a diffraction efficiency of a diffracted light with an order used for optical fiber coupling out of diffracted lights from the diffraction lens is η, the following formula is satisfied: 30%≤η≤37%. 9. The coupling lens according to claim 1, 2, or 6, wherein a wavelength λ of the semiconductor laser satisfies the following formula: 700 nm0of the zero-order diffracted light satisfies the following formula: 25%≤η0≤40%. 17. The coupling lens according to claim 16, wherein a diffraction efficiency η0of the zero-order diffracted light satisfies the following formula: 30%≤η0≤37%. 18. A semiconductor laser module, comprising, at least: a semiconductor laser; an optical fiber; a fixing member for fixing an incident end of the optical fiber; and a coupling lens for allowing a beam of light emitted from the semiconductor laser to form an image on the incident end of the optical fiber, wherein the coupling lens is the coupling lens according to claim 16. 19. The semiconductor l