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A biventricular cardiac prosthesis has a flow balance control system to balance blood flow through the left and right sides of the prosthesis to maintain a patient's left atrial pressure within physiologic bounds. The prosthesis can be configured to have flow characteristics so that a signal represe

A biventricular cardiac prosthesis has a flow balance control system to balance blood flow through the left and right sides of the prosthesis to maintain a patient's left atrial pressure within physiologic bounds. The prosthesis can be configured to have flow characteristics so that a signal representative of the difference in hydraulic pumping pressures on the left and right sides of the prosthesis is representative of the difference between left and right atrial pressures of a patient having the prosthesis implanted. This signal can be used as a control signal to drive the prosthesis so that left atrial pressure is approximately equal to right atrial pressure, and within physiologic bounds. A specific prosthesis includes left and right pumping sections, each having a blood pumping chamber and a hydraulic fluid chamber, with a reciprocating hydraulic pump driving systole alternately on the right and left sides. A hydraulic balance chamber is hydraulically coupled to the right hydraulic fluid chamber and an adjustable occluder varies flow resistance through the hydraulic coupling. The occluder can be adjusted based on the control signal to adjustably derate right side blood flow to achieve the desired pressure balance, or the occluder can be adjusted based on fluid communication with sources of pressure in the prosthesis that are representative of right and left atrial pressures.

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A biventricular cardiac prosthesis has a flow balance control system to balance blood flow through the left and right sides of the prosthesis to maintain a patient's left atrial pressure within physiologic bounds. The prosthesis can be configured to have flow characteristics so that a signal represe

A biventricular cardiac prosthesis has a flow balance control system to balance blood flow through the left and right sides of the prosthesis to maintain a patient's left atrial pressure within physiologic bounds. The prosthesis can be configured to have flow characteristics so that a signal representative of the difference in hydraulic pumping pressures on the left and right sides of the prosthesis is representative of the difference between left and right atrial pressures of a patient having the prosthesis implanted. This signal can be used as a control signal to drive the prosthesis so that left atrial pressure is approximately equal to right atrial pressure, and within physiologic bounds. A specific prosthesis includes left and right pumping sections, each having a blood pumping chamber and a hydraulic fluid chamber, with a reciprocating hydraulic pump driving systole alternately on the right and left sides. A hydraulic balance chamber is hydraulically coupled to the right hydraulic fluid chamber and an adjustable occluder varies flow resistance through the hydraulic coupling. The occluder can be adjusted based on the control signal to adjustably derate right side blood flow to achieve the desired pressure balance, or the occluder can be adjusted based on fluid communication with sources of pressure in the prosthesis that are representative of right and left atrial pressures. is hydrogen peroxide which is added as a 3 to 50 percent by weight aqueous solution. 6. The process of claim 1, wherein the process contains a recrystallizing step (e) comprising the steps of: combining the collected phenyl ester salt with a recrystallization solvent; heating the collected phenyl ester salt and the recrystallization solvent to dissolve the phenyl ester salt and form a recrystallization solution; cooling the recrystallization solution to crystallize the phenyl ester salt; and collecting the phenyl ester salt. 7. A process according to claim 6, wherein said recrystallization solvent is selected from proprionic acid, acetic acid, methanol/water, and mixtures thereof. 8. A process according to claim 6, wherein step (e) further comprises the steps of: washing the phenyl ester salt; and drying the phenyl ester salt. 9. A process according to claim 8, wherein the drying step dries the phenyl ester salt in a drying device selected from a ring dryer, a tray dryer, and a rotary-cone vacuum dryer. 10. A process according to claim 1, wherein the optional drying step (d) dries the collected phenyl ester salt in a drying device selected from a ring dryer, a tray dryer, and a rotary-cone vacuum dryer. 11. The process of claim 1, wherein the process contains a recrystallizing step (e) comprising the steps of: combining the collected phenyl ester salt with water; heating the collected phenyl ester salt and the water to dissolve the phenyl ester salt and form an aqueous solution; adjusting the pH of the aqueous solution; cooling the aqueous solution to crystallize the phenyl ester salt; adding a co-solvent to the aqueous solution; and collecting the phenyl ester salt. 12. A process according to claim 11, further comprising the steps of: washing the phenyl ester salt; and drying the phenyl ester salt. 13. A process according to claim 12, wherein the drying step dries the phenyl ester salt in a drying device selected from a ring dryer, a tray dryer, and a rotary-cone vacuum dryer. 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