This invention provides crosslinkable-group-containing polyimides of various known thermoplastic polyimide backbone structures, which are provided with far better heat resistance, chemical resistance and mechanical properties than known polyimides of the structures without impairing excellent moldab
This invention provides crosslinkable-group-containing polyimides of various known thermoplastic polyimide backbone structures, which are provided with far better heat resistance, chemical resistance and mechanical properties than known polyimides of the structures without impairing excellent moldability or formability, superb sliding property, low water absorption property, outstanding electrical properties, high thermal oxidation stability and high radiation resistance, all of which are inherent to the structures.
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This invention provides crosslinkable-group-containing polyimides of various known thermoplastic polyimide backbone structures, which are provided with far better heat resistance, chemical resistance and mechanical properties than known polyimides of the structures without impairing excellent moldab
This invention provides crosslinkable-group-containing polyimides of various known thermoplastic polyimide backbone structures, which are provided with far better heat resistance, chemical resistance and mechanical properties than known polyimides of the structures without impairing excellent moldability or formability, superb sliding property, low water absorption property, outstanding electrical properties, high thermal oxidation stability and high radiation resistance, all of which are inherent to the structures. t, et al., "A Very Strong Enhancer is Located Upstream of an Immediate Early Gene of Human Cytomegalovirus," Cell, 41:521-520 (1985). Brody, et al., "Adenovirus-Mediated In Vivo Gene Transfer," NY Acad. Sci., 716:90-101 (1994). Cockell, et al., "Identification of a Cell-Specific DNA-Binding Activity that Interacts with a Transcriptional Activator of Genes Expressed in the Acinar Pancreas," Mol. Cell. Biol., 9:2464-2476 (1989). Coghlan, "Gene Dream Fades Away," New Scientist, (Nov. 1995):14-15. Crystal, "Transfer of Genes to Humans: Early Lessons and Obstacles to Success," Science, 270:404-410 (1995). Elango, et al., "Molecular Cloning and Characterization of Six Genes, Determination of Gene Order and Intergenic Sequences and Leader Sequence of Mumps Virus," J. Gen. Virol., 69:2893-2900 (1988). Felgner, et al., "Lipofection: A Highly Efficient, Lipid-Mediated DNA-Transfection Procedure," Proc. Nat'l. Acad. Sci. USA, 84:7413-7417 (1987). Fynan, et al., "DNA Vaccines: Protective Immunizations by Parenteral, Mucosal, and Gene-Gun Inoculations," Proc. Nat'l. Acad. Sci. USA, 90:11478-11482 (1993). Gerrard, et al., "Towards Gene Therapy for Haemophelia B Using Primary Human Keratinocytes," Nat. Genet., 3:180 (1993). Gitschier, et al., "Characterization of the Human Factor VIII Gene," Nature, 312:326-330 (1984). Gorman, et al., "The Rous Sarcoma Virus Long Terminal Repeat is a Strong Promoter when Introduced into a Variety of Eukaryotic Cells by DNA-Mediated Transfection," Proc. Nat'l. Acad. Sci. USA, 79:6777-6781 (1982). Grendell, et al., "Effect of Changes in Circulating Amylase Levels on Amylase Output in Bile," The American Physiological Socitey, G54-G59 (1982). Groot, et al., "The Human α-Amylase Multigene Family Consists of Haplotypes with Variable Numbers of Genes," Genomics, 5:29-42 (1989). Gunzberg, et al., "Virus vector design in gene therapy," Molecular Medicine Today 410-417 (1995). Hagenbuchle, et al., "Expression of Mausy Amy-2aAlpha-Amylase Genes is Regulated by Strong Pancreas-Specific Promoters," J. Mol. Biol., 185:285-293 (1985). Hewitt, et al., "Human Gastric Intrinsic Factor: Characterization of cDNA and Genomic Clones and Localization to Human Chromosome 11," Genomics, 10:432-440 (1991). Jones, et al., "A Salivary Amylase Transgene is Efficiently Expressed in Livery but Not in Parotid Gland of Transgenic Mice," Nucleic Acids Res., 17(6):6613-6623 (1989). Korman, et al., "Expression of Human Class II Major Histocompatibility Complex Antigens Using Retrovirus Vectors," Proc. Nat'l. Acad. Sci. USA, 84:2150-2154 (1987). Kozarsky, et al., "Adenovirus-Mediated Correction of the Genetic Defect in Hepatocytes from Patients with Familial Hypercholesterolmia," Somat. Cell Mol. Genet., 19(5):449-458 (1993). Kwano, et al., "Complete Nucleotide Sequence of the Matrix Gene of Human Parainfluenza Type 2 Virus and Expression of the M Protein in Bacteria," Virol., 179:857-861 (1990). Ledley, "Nonviral gene therapy: the promise of genes as pharmaceutical products," Human Gene Therapy, 6:1129-1144 (1995). Lowry, et al., "Protein Measurement with the Folin Phenol Reagent," J. Biol. Chem., 193:265-275 (1951). Maeda, et al., "Adenovirus-Mediated Transfer of Human Lipase Complementary DNA to the Gallbladder," Gastroentreology, 106:1638-1644 (1994). Marshall, et al., "Less Hype, Mor Biology Needed for Gene Therapy," Science, 270:1751 (1995). Marshall, "Gene Therapy's Growing Pains," Science, 269(5227):1050 (1995). Martial, et al., "Human Growth Hormone: Complementary DNA Cloning and Expression in Bacteria," Biotechnology, 24:293-298 (1992). Mastrangeli, et al., "Direct In Vivo Adenovirus-Mediated Gene Transfer to Salivary Glands," Am. J. Physiol., 266:(6, part 1):G1156-55 (1994). Mastrangelo, et al., "Gene Therapy for Human Cancer: An Essay for Clinicians," Seminars in Oncology, 23:4-21 (1996). Miller, et al., "Targeted Vectors for Gene Therapy," FASEB J., 9(2):190-199 (1995). Miyasaka, et al., "E ndocrine Secretion of α-Amylase by the Process by the Pancreas," American Physiological Society, G170-G175 (1981). Morgan, et al., "Expression of an Exogenous Growth Hormone Gene by Transplantable Human Epidermal Cells," Science, 237:1476-1479 (1987). Morsy, et al., "Progress Toward Human Gene Therapy," JAMA, 270:2338-2345 (1993). Mulligan, "The Basic Science of Gene Therapy," Science, 260:926-932 (1993). Newgard, et al., "Molecular Engineering of the Pancreatic β-Cell," J. Lab. Clin. Med., 122(4):356-363 (1993). Orkin, et al., "Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy," Dec. 7, 1995. Pittet, et al., "Mouse Alpha-Amylase Loci, Amy-2aand Amy-1a,are Closely Linked," J. Mol. Biol., 182:359-365 (1985). Ramakrishna, et al., "Gene Therapy for Exorcrine Pancreatic Insufficiency," Gastroenterology, 106(6):1711-1713 (1994). Robins, et al., "Retrotransposons sand the Evolution of Mammalian Gene Expression," Genetica, 86:191-201 (1992). Rosenfeld, et al., "Adenovirus-Mediated Transfer of a Recombinant αI-Antitrypsin Gene to the Lung Epithelium In Vivo," Science, 252:431-434 (1991). Rosenfeld, et al., "In Vivo Transfer of the Human Cystic Fibrosis Transmembrane Conductance Regulator Gene to the Airway Epithelium," Cell, 68:143-155 (1992). Samara, et al., "Molecular Biology and Therapy of Disease," The American Journal of Surgery, 165:720-727 (1993). Samuelson, et al., "Expression of the Human Amylase Genes: Recent Origin of a Salivary Amylase Promoter from an Actin Pseudogene," Nucleic Acids Res., 16:8261-8276 (1988). Schibler, et al., "Structural Arrangement of and Tissue-Specific Expression of the Two Murine Alpha-Amylase Loci Amy-1 and Amy-2," Oxf. Surv. Eukaryot. Genes, 3:210-234 (1986). Sierra, et al., "Different Tissue-Specific Expression of the Amylase Gene Amy-I in Mice and Rats," Mol. Cell. Biol., 6(11):4067-4076 (1986). Stewart, et al., "Insulin Delivery by Somatic Cell Gene Therapy," J. Mol. Endocrinol., 11(3):335-341 (1993). Stewart, et al., "Insulin-Releasing Pituitary Cells as a Model for Somatic Cell Gene Therapy," J. Mol. Endocrinol., 143:339-343 (1994). Takeuchi, et al., "In Vitro Transcription and Replication of the Mumps Virus Genome," Archiv. Virol., 128:177-183 (1993). Tanabayashi, et al., "Expression of Mumps Virus Glycoproteins in Mammalian Cells from Cloned cDNA's: Both F and HN Proteins are Required for Cell Fusion," Virol., 187:801-804 (1992). Tanabayashi, et al., "Identification of an Amino Acid that Defines the Fusogenicity of Mumps Virus," J. Virol., 67:2928-2931 (1993). Ting, et al., "Endogenous Retroviral Sequences are Required for Tissue-Specific Expression fo a Human Salivary Amylase Gland," Genes Dev., 6:1457-1465 (1992). Tomita, et al., "A Novel Type of Human α-Amylase Produced in Lung Carcinoid Tumor," Gene, 76:11-18 (1989). Towbin, et al., "Electrophoretic Transfer of Proteins from Polyacrylamide Gels to Nitrocellulose Sheets: Procedure and Some Applications," Proc. Nat'l. Acad. Sci. USA, 76:4350-4354 (1979). Wolff, et al., "Direct Gene Transfer into Mouse Muscle In Vivo," Science, 247:1465-1468 (1990). Wood, et al., "Expression of Active Human Factor VIII from Recombinant DNA Clones," Nature, 312:330-337 (1984). Yang, et al., "In Vivo and In Vitro Gene Transfer to Mammalian Somatic Cells by Particle Bombardment," Proc. Nat'l. Acad. Sci. USA, 87:9568-9572 (1990). Taniguchi, et al., "Constant delivery of proinsulin by encapsulation of transfected cells," J. Surgical Res., 70:41-45 (1997). Adesanya, et al., "Immediate Inflammatory Responses to Adenovirus-Mediated Gene Transfer in Rat Salivary Glands," Human Gene Therapy, 7:1085-1093 (Jun. 10, 1996). Barka, et al., "Retrovirus-Mediated Gene Transfer into Salivary Glands In Vivo,"Human Gene Therapy, 7:613-618 (Mar. 20, 1996). Buckel, et al., "Recombinant proteins for therapy," TiPS, 17:450 (1996). Curiel, et al., "Gene transfer to respiratory epi
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