초록 ▼

A device and method of use for securing and coring of tumors within the body during a biopsy of the tumor, specifically breast tumors. An adhesion probe for securing the tumor is described. The probe secures the tumor by piercing the tumor and providing a coolant to the distal tip to cool the tip. T

A device and method of use for securing and coring of tumors within the body during a biopsy of the tumor, specifically breast tumors. An adhesion probe for securing the tumor is described. The probe secures the tumor by piercing the tumor and providing a coolant to the distal tip to cool the tip. The cooled tip adheres to the tumor. A coring instrument adapted for cutting a core sample of the tumor is described. The instrument is provided with a cannula that can cut a core sample of the tumor. The instrument is adapted for use with the probe with the probe fitting within the cannula. The instrument can be used in conjunction with the probe to secure and core a sample of the tumor for biopsy.

대표청구항 ▼

A device and method of use for securing and coring of tumors within the body during a biopsy of the tumor, specifically breast tumors. An adhesion probe for securing the tumor is described. The probe secures the tumor by piercing the tumor and providing a coolant to the distal tip to cool the tip. T

A device and method of use for securing and coring of tumors within the body during a biopsy of the tumor, specifically breast tumors. An adhesion probe for securing the tumor is described. The probe secures the tumor by piercing the tumor and providing a coolant to the distal tip to cool the tip. The cooled tip adheres to the tumor. A coring instrument adapted for cutting a core sample of the tumor is described. The instrument is provided with a cannula that can cut a core sample of the tumor. The instrument is adapted for use with the probe with the probe fitting within the cannula. The instrument can be used in conjunction with the probe to secure and core a sample of the tumor for biopsy. et al., Optical glucose sensing in biological fluids: an overview, Journal of Biomedical Optics, 5(1), 5-16, Jan. 2000. D'Arrigo, GlucoWatch Monitor Poised For Approval, Diabetes Forecast, 43-44, Mar. 2000. Svedman, et al., Skin mini-erosion technique for monitoring metabolites in interstitial fluid: its feasibility demonstrated by OGTT results in diabetic and non-diabetic subjects, Scand J Clin Lab Invest, 59(2):115-23, Apr. 1999. Rebrin et al., Subcutaneous glucose predicts plasma glucose independent of insulin: implications for continuous monitoring, Am J Physiol, 277 (3 pt 1): E561-71, Sep. 1999. Collison et al., Analytical characterization of electrochemical biosensor test strips for measurement of glucose in low-volume interstitial fluid samples, Clin Chem, 45(9):1665-73, Sep. 1999. Pfohl et al., Spot glucose measurement in epidermal interstitial fluid--an alternative to capillary blood glucose estimation?, Exp Clin Endocrinol Diabetes, 108(1):1-4, 2000. Kumetrix, Inc., Painless blood glucose monitoring, courtesy of the mosquito, Start-Up, p. 27, Dec. 1999. Taking the "ouch" out of needles: arrays of "microneedles" offer new technique for drug delivery, Science Daily, 1999. f piezoelectric elements being arranged in alternating positions with respect to a second set of piezoelectric elements in a dual-frequency ultrasonic linear array transducer; (c) introducing said acoustic pulses into an area of a medium or body to be ultrasonically imaged through multiple acoustic impedance matching layers each of whose thickness is one quarter of the wavelength of the higher of the center resonant frequencies of said first set of piezoelectric elements and said second set of piezoelectric elements, wherein the number of said acoustic impedance matching layers is equal to or twice the ratio of the higher of said center resonant frequencies to the lower of said center resonant frequencies; (d) receiving echoes at a second harmonic or subharmonic frequency in said second set of piezoelectric elements with center resonant frequency equal to said second harmonic or subharmonic frequency, thereby converting them into a first set of received electrical pulses; (e) beamforming said first set of received electrical pulses so as to focus on second harmonic or subharmonic echoes originating from a specified depth zone within said medium or said body; (f) assembling a second harmonic or subharmonic image by scan converting all image vectors comprised of intensities mapped from said first set of received electrical pulses; and (g) displaying said second harmonic or subharmonic image. 7. A method according to claim 6 further comprising the steps of: (h) receiving echoes at said fundamental-frequency in said first set of piezoelectric elements, thereby converting them into a second set of received electrical pulses