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Method for marking samples 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • C12Q-001/68
  • C12M-001/34
  • C07K-014/00
  • C07H-021/02
  • C07H-021/04
출원번호 US-0585556 (2000-06-02)
발명자 / 주소
  • Fodor, Stephen P. A.
  • Solas, Dennis W.
  • Dower, William J.
출원인 / 주소
  • Affymetrix, Inc.
대리인 / 주소
    Morgan, Lewis & Bockius LLP
인용정보 피인용 횟수 : 89  인용 특허 : 165

초록

The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and

대표청구항

The present invention provides methods and apparatus for sequencing, fingerprinting and mapping biological macromolecules, typically biological polymers. The methods make use of a plurality of sequence specific recognition reagents which can also be used for classification of biological samples, and

이 특허에 인용된 특허 (165)

  1. Stavrianopoulos Jannis (New York NY) Rabbani Elazar (New York NY) Abrams Samuel B. (New York NY) Wetmur James G. (Scardsdale NY), Analyte detection by means of energy transfer.
  2. Malmros Mark K. (P.O. Box 106 Washington Crossing PA 18977), Analytical device having semiconductive organic polymeric element associated with analyte-binding substance.
  3. Wertz Richard K. (Sacramento CA) Cook Albert M. (Sacramento CA) Hathaway James C. (Sacramento CA), Antibiotic susceptibility testing.
  4. Southern Edwin (Oxford GB2), Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays.
  5. Saccocio Edward J. (1790 Sugar Run Trail Bellbrook OH 45305), Apparatus and method for determining gel rate of polymerizable compositions.
  6. Elings, Virgil B.; Nicoli, David F., Apparatus and method for homogeneous immunoassay.
  7. Dixon Arthur E. (41 Lane Crescent Kitchener ; Ontario CAX N2K 1P2) Damaskinos Savvas (Kitchener CAX) Bowron John W. (Waterloo CAX), Apparatus and method for method for spatially- and spectrally-resolved measurements.
  8. Steel Samuel (3817 Davis Pl. ; Apt. 6 Washington DC 20007), Apparatus for a solid phase synthesis of peptide analogs.
  9. Hamill Brendan J. (11 ; Napier Square Livingston EH54 5DG GB6), Apparatus for the chemical synthesis of oligonucleotides.
  10. Groebler Bernhard (Jena-Lobeda DDX), Apparatus for the graphic representation and analysis of fluorescence signals.
  11. Fodor Stephen P. A. (Palo Alto CA) Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Stryer Lubert (Stanford CA), Array of oligonucleotides on a solid substrate.
  12. Palva Airi M. (Helsinki FIX) Ranki Tuula M. (Espoo FIX) Sderlund Hans E. (Espoo FIX), Arrays of alternating nucleic acid fragments for hybridization arrays.
  13. Fodor Stephen P.A. ; Stryer Lubert ; Read J. Leighton ; Pirrung Michael C., Arrays of materials attached to a substrate.
  14. Dattagupta Nanibhushan (West Haven CT) Rae Peter M. M. (Hamden CT) Rabin Daniel U. (Branford CT) Huguenel Edward D. (Guilford CT), Assay for nucleic acid sequences in an unpurified sample.
  15. Taub Floyd (Rockville MD), Assay for nucleic acid sequences, particularly genetic lesions, using interactive labels.
  16. Huang Henry V. (232 S. Catalina Pasadena CA 91106), Automated method for quantitative analysis of biological fluids.
  17. Andrus William A. (San Francisco CA) McCollum Christie D. (Foster City CA) Zon Gerald (San Carlos CA), Automated system for polynucleotide synthesis and purification.
  18. Yabe Ryohei (Katsuta JPX) Matsushita Hajime (Katsuta JPX), Automatic focusing control method for microscope.
  19. Fujii Norio (Urawa JPX) Kawahara Atsushi (Tokyo JPX) Sawada Masahiro (Kawasaki JPX), Automatic focusing device of a microscope.
  20. Glass John D. (Shoreham NY), Benzylthioether-linked solid support-bound thiol compounds and method for peptide synthesis.
  21. Guire Patrick E. (Eden Prairie MN), Binding reagents and methods.
  22. Guire Patrick E. (Eden Prairie MN), Biocompatible coating for solid surfaces.
  23. Dandekar Thomas (Rankestrasse 2 8000 Mnchen 40 DEX), Biosensor.
  24. Paulus Henry P. (Boston MA), Bispecific antibody determinants.
  25. Schultz Peter (Oakland CA), Catalytic and reactive polypeptides and methods for their preparation and use.
  26. Brenner Sydney,GB2, Combinatorial libraries and methods for their use.
  27. Pinkel Daniel ; Albertson Donna,GBX ; Gray Joe W., Comparative fluorescence hybridization to nucleic acid arrays.
  28. Still W. Clark (Clinton NY) Wigler Michael H. (Lloyd Harbor NY) Ohlmeyer Michael H. J. (Plainsboro NJ) Dillard Lawrence W. (Plainsboro NJ) Reader John C. (Princeton NJ), Complex combinatorial chemical libraries encoded with tags.
  29. Rabbani Elazar (New York NY) Engelhardt Dean L. (New York NY), Composition and method for the detection of the presence of a polynucleotide sequence of interest.
  30. Ip Nancy Y. (Stamford CT) Baum Howard J. (Stony Point NY), Compositions and methods useful for genetic analysis.
  31. Brenner Sydney (Cambridge GB2), Compositions for sorting polynucleotides.
  32. Hubbell Earl A. (Mt. View CA) Lipshutz Robert J. (Palo Alto CA) Morris Macdonald S. (San Jose CA) Winkler James L. (Palo Alto CA), Computer-aided engineering system for design of sequence arrays and lithographic masks.
  33. Hubbell Earl A. (Mt. View CA) Morris MacDonald S. (San Jose CA) Winkler James L. (Palo Alto CA), Computer-aided engineering system for design of sequence arrays and lithographic masks.
  34. Omichinski James G. (Potomac MD) Fassina Giorgio (Padova MD ITX) Olson Arthur D. (Silver Spring MD) Thorgeirsson Snorri S. (Bethesda MD), Computer-assisted design of anti-peptides based on the amino acid sequence of a target peptide.
  35. Kelderman Herman F. (Berkeley CA) Fein Michael E. (Mountain View CA) Loh Alan E. (Sunnyvale CA) Adams Arnold (Goleta CA) Neukermans Armand P. (Palo Alto CA), Confocal measuring microscope with automatic focusing.
  36. Dattagupta Nanibhushan (New Haven CT) Crothers Donald M. (Northford CT), Coupling of nucleic acids to solid support by photochemical methods.
  37. Dattagupta, Nanibhushan; Crothers, Donald M., Coupling of nucleic acids to solid support by photochemical methods.
  38. Hollenberg Cornelis P. (Chopinstrasse 7 ; 4000 Dusseldorf DEX) di Mauro Ernesto (Via Andrea Fulvio 10 ; 00162 Rome ITX), DNA and DNA technology for the construction of networks to be used in chip construction and chip production (DNA-chips).
  39. Chehab Farid F. (San Francisco CA), DNA detection by color complementation.
  40. Smith Lloyd M. (South Pasadena CA) Fung Steven (Palo Alto CA), Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for t.
  41. Longiaru Mathew (West Orange NJ) Silver Sheryl B. (Fort Lee NJ) Sulzinski Michael A. (Spring Valley NY), Detection of chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes.
  42. Gordon Julian (Arlesheim CHX) Hawkes Richard (Allschwil IL CHX) Niday Evelyn (Arlington Heights IL) Towbin Harry (Allschwil CHX), Devices and kits for immunological analysis.
  43. Lowe, Christopher R.; Earley, Fergus G. P., Diagnostic device incorporating a biochemical ligand.
  44. Shuber Anthony P., Direct sequence identification of mutations by cleavage- and ligation-associated mutation-specific sequencing.
  45. Southern Edwin (Oxford GBX), Electrochemical treatment of surfaces.
  46. Mandecki Wlodek (516 Hemlock La. Libertyville IL 60048), Electronically-indexed solid-phase assay for biomolecules.
  47. Lerner Richard (La Jolla CA) Janda Kim (San Diego CA) Brenner Sydney (Cambridge GB2), Encoded combinatorial chemical libraries.
  48. Brakel Christine L. (Brightwaters NY) Cook Alan F. (Cedar Groove NJ) Vuocolo Edmund (Bronx NY), End labeled nucleotide probe.
  49. Feyrer Clyde D. (Portland OR) Gordon N. Ross (Kennewick WA) Skiens W. Eugene (Wilsonville OR), Erasable optical data storage medium.
  50. Goldman Abraham (Kendall Park NJ), Etching method using a hardened PVA stencil.
  51. Walt David R. ; Michael Karri Lynn, Fiber optic sensor with encoded microspheres.
  52. Schenck John F. (Schenectady NY), Field effect transistor for detection of biological reactions.
  53. Kramer Peter B. (Newton Centre MA), Fluorescence polarization immunoassay for heavy antigens.
  54. Kronick Melvyn N. (Palo Alto CA) Little William A. (Palo Alto CA), Fluorescent immunoassay employing total reflection for activation.
  55. Ullman Edwin F. (Atherton CA), Fluorescent multiparameter particle analysis.
  56. Pinkel Daniel (Walnut Creek CA) Gray Joe (San Francisco CA), High density array fabrication and readout method for a fiber optic biosensor.
  57. Schnur Joel M. (6009 Lincolnwood Ct. Burke VA 22015) Schoen Paul E. (5006 Taney Ave. Alexandria VA 22304) Peckerar Martin C. (12917 Buccaneer Rd. Silver Spring MD 20904) Marrian Christie R. K. (6805 , High resolution patterning on solid substrates.
  58. Potter Huntington (Somerville MA), Hybridization assay and kit therefor.
  59. Gillespie David (Glenmoore PA) Brodsky Isadore (Narberth PA) Bresser Joel (Aldan PA), Immobilization of message RNA directly from cells onto filter material.
  60. Holmes Christopher P. (Sunnyvale CA), Immobilized molecular synthesis of systematically substituted compounds.
  61. Stavrianopoulos Jannis (New York NY) Yang Heuy-Lang (Tenafly NJ) Kelker Norman E. (New York NY), In vivo labelling of polynucleotide sequences.
  62. Singer Robert H. (Shrewsbury MA) Lawrence Jeanne B. (Mapleville RI), In-situ hybridization to detect nucleic acid sequences in morphologically intact cells.
  63. Tanke Hendrikus J. (Rijnsburg NLX) Slats Johannes C. (Noordwikjerhout NLX) Ploem Johan S. (Oegstgeest NLX), Inorganic phosphor labelled macromolecules; a process for their preparation and their use for immunological or immunocyt.
  64. Letsinger Robert L. (Wilmette IL) Singman Charles N. (Teaneck NJ), Labile anchors for solid phase polynucleotide synthesis.
  65. Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Fodor Stephen P. A. (Palo Alto CA) Stryer Lubert (Stanford CA), Large scale photolithographic solid phase synthesis of an array of polymers.
  66. Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Fodor Stephen P. A. (Palo Alto CA) Stryer Lubert (Stanford CA), Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof.
  67. Mathies Richard A. (Contra Costa CA) Peck Konan (Contra Costa CA), Laser excited confocal microscope fluorescence scanner and method.
  68. Takayama Norikazu (Odawara JPX) Ushijima Nobuyoshi (Odawara JPX) Kobashi Tetsuzo (Odawara JPX) Sato Masahiko (Odawara JPX) Yano Yoshihiko (Hiratuka JPX) Isozaki Jun (Kashiwa JPX) Fujii Kousuke (Kogan, Magnetic disk apparatus.
  69. Houghten Richard A. (Solana Beach CA), Means for sequential solid phase organic synthesis and methods using the same.
  70. Mitchell David H. (Pacific Palisades CA) Mitchell Ralph M. (Pacific Palisades CA), Measurement of ligand/anti-ligand interactions using bulk conductance.
  71. Koester Hubert (Concord MA) Coull James M. (Acton MA), Membranes with bound oligonucleotides and peptides.
  72. Brennan Thomas M. (San Francisco CA), Method and apparatus for conducting an array of chemical reactions on a support surface.
  73. Lebacq Philippe (Paris FRX), Method and apparatus for high security crypto-marking for protecting valuable objects.
  74. Rothberg Jonathan Marc ; Deem Michael W. ; Simpson John W., Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing.
  75. Fodor Stephen P. A. (Palo Alto CA) Mazzola Laura T. (Redwood City CA), Method and apparatus for measuring binding affinity.
  76. Stavrianopoulos Jannis G. (New York NY) Kirtikar Dollie (Elmhurst NY) Johnston Kenneth H. (New York NY) Thalenfeld Barbara E. (New York NY), Method and structures employing chemically-labelled polynucleotide probes.
  77. Erlich Henry A. (Oakland CA) Horn Glenn T. (Framingham MA) Bugawan Teodorica (San Leandro CA) Begovich Ann B. (El Cerrito CA), Method for HLA DP typing.
  78. Tabata Mitsuo (Yokohama JPX) Tojo Toru (Kanagawa JPX) Shimozono Hiroaki (Tokyo JPX), Method for aligning first and second objects relative to each other and apparatus for practicing this method.
  79. Augenlicht Leonard (Stamford CT), Method for detecting pathological conditions.
  80. Geysen Hendrik M. (Knoxfield AUX), Method for determining mimotopes.
  81. Macioszek Jerzy A. (Gurnee IL) Robinson John M. (Gurnee IL), Method for elimination of rheumatoid factor interference in diagnostic assays.
  82. Zeiger Allen R. (Philadelphia PA), Method for preventing deletion sequences in solid phase synthesis.
  83. Farnsworth Vincent (Agoura CA), Method for protein and peptide sequencing using derivatized glass supports.
  84. White Bruce A. (Farmington CT) Bancroft F. Carter (Brooklyn NY), Method for simple analysis of relative nucleic acid levels in multiple small samples by cytoplasmic dot hybridization.
  85. Arwin ; Hans R. ; Lundstrom ; Kurt I., Method for studying enzymatic and other biochemical reactions.
  86. Landegren Ulf (Pasadena CA) Hood Leroy (Pasadena CA), Method of detecting a nucleotide change in nucleic acids.
  87. Fung Steven (Palo Alto CA) Woo Sam L. (Redwood City CA) Haugland Richard P. (Junction City OR) Menchen Steven M. (Hayward CA) Connell Charles R. (Redwood City CA), Method of detecting electrophoretically separated oligonucleotides.
  88. Fodor Stephen P.A. ; Solas Dennis W. ; Dower William J., Method of detecting nucleic acids.
  89. Drmanac Radoje T. (Beograd YUX) Crkvenjakov Radomir B. (Beograd YUX), Method of determining an ordered sequence of subfragments of a nucleic acid fragment by hybridization of oligonucleotide.
  90. Veldkamp Wilfrid B. (Lexington MA) Swanson Gary J. (Lexington MA), Method of fabricating high efficiency binary planar optical elements.
  91. Bahl Chander (Flemington NJ) Lang Rhonda (Lawrenceville NJ) Mendoza Leopoldo G. (Madison WI), Method of immobilizing nucleic acid on a solid surface for use in nucleic acid hybridization assays.
  92. Guire Patrick E. (Eden Prairie MN), Method of improving the biocompatibility of solid surfaces.
  93. Gray Joe W. (Livermore CA) Pinkel Daniel (Walnut Creek CA), Method of preparing and applying single stranded DNA probes to double stranded target DNAs in situ.
  94. Drmanac Radoje T. (Belgrade YUX) Crkvenjakov Radomir B. (Belgrade YUX), Method of sequencing by hybridization of oligonucleotide probes.
  95. Drmanac Radoje T. (Beograd YUX) Crkvenjakov Radomir B. (Beograd YUX), Method of sequencing by hybridization of oligonucleotide probes.
  96. Drmanac Radoje T. (Zvecanska 46 Beograd 11000) Crkvenjakov Radomir B. (Bulevar JNA 118 Beograd YUX 11000), Method of sequencing of genomes by hybridization of oligonucleotide probes.
  97. Drmanac Radoje T. (Beograd YUX) Crkvenjakov Radomir B. (Beograd YUX), Method of sequencing of genoms by hybridization of oligonucleotide probes.
  98. Brenner Sydney,GB2, Method of sorting polynucleotides.
  99. Apple Raymond J. (San Francisco CA) Erlich Henry A. (Oakland CA) Griffith Robert L. (Belmont CA) Scharf Stephen J. (Albany CA), Methods and reagents for HLA DRbeta DNA typing.
  100. Gray Joe W. (Livermore CA) Pinkel Daniel (Walnut Creek CA), Methods for chromosome-specific staining.
  101. Brown Patrick O. ; Shalon Tidhar Dari, Methods for fabricating microarrays of biological samples.
  102. Glahn et al., Methods for measuring relative amounts of nucleic acids in a complex mixture and retrieval of specific sequences therefrom.
  103. Brenner Sydney (Cambridge GB2), Methods for sorting polynucleotides using oligonucleotide tags.
  104. Dollinger Gavin D. (San Francisco CA), Methods for tagging and tracing materials with nucleic acids.
  105. Khrapko Konstantin R. (Moscow RUX) Khorlin Alexandr A. (Moscow RUX) Ivanov Igor B. (Moskovskaya RUX) Ershov Gennady M. (Moscow RUX) Lysov Jury P. (Moscow RUX) Florentiev Vladimir L. (Moscow RUX) Mirz, Methods of DNA sequencing by hybridization based on optimizing concentration of matrix-bound oligonucleotide and device.
  106. Pazos Jose F. (Claymont DE), Methods of developing photopolymerizable compositions containing an 0-nitroaromatic compound as photoinhibitor.
  107. Madou Marc J. (Palo Alto CA) Otagawa Takaaki (Fremont CA), Microelectrochemical sensor and sensor array.
  108. Beattie Kenneth L., Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions.
  109. Eisenberg Sylvan (San Francisco CA), Microingredient containing tracer.
  110. Brenner Sydney (Cambridge GB2), Minimally cross-hybridizing sets of oligonucleotide tags.
  111. Ward David C. (Guilford CT) Langer Pennina R. (Monsey NY) Waldrop ; III Alexander A. (Charlottesville VA), Modified nucleotides and methods of preparing and using same.
  112. Nelson Paul S. (Union City CA), Multifunctional controlled pore glass reagent for solid phase oligonucleotide synthesis.
  113. Urdea Mickey S. (San Francisco CA) Warner Brian D. (Eau Claire WI), Multiple reactor system and method for polynucleotide synthesis.
  114. Platzer Stephan J. W. (Califon NJ), Negative working color proofing process comprising diazo compound and polyvinyl acetal/polyvinyl alcohol/polyvinyl aceta.
  115. Wang Chang-Ning J. (Chelmsford MA) Klotz Lynn C. (Cambridge MA), Nucleic acid hybridization assays.
  116. Macevicz Stephen C. (21890 Rucker Dr. Cupertino CA 95014), Nucleic acid sequence determination by multiple mixed oligonucleotide probes.
  117. Caruthers Marvin H. (Boulder CO) Matteucci Mark D. (San Francisco CA), Nucleosides useful in the preparation of polynucleotides.
  118. Foote Robert S. (105 Elliot Cir. Oak Ridge TN 37830) Sachleben Richard A. (1105 Hickory Trail Knoxville TN 37932), Nucleosides with 5′-O-photolabile protecting groups.
  119. Brenner Sydney,GB2 ; Albrecht Glenn ; Macevicz Stephen C., Oligonucleotide tags for sorting and identification.
  120. Hollis Mark A. (Concord MA) Ehrlich Daniel J. (Lexington MA) Murphy R. Allen (Boxboro MA) Kosicki Bernard B. (Acton MA) Rathman Dennis D. (Ashland MA) Chen Chang-Lee (Sudbury MA) Mathews Richard H. (, Optical and electrical methods and apparatus for molecule detection.
  121. Hollis Mark A. ; Ehrlich Daniel J. ; Murphy R. Allen ; Kosicki Bernard B. ; Rathman Dennis D. ; Mathews Richard H. ; Burke Barry E. ; Eggers Mitch D. ; Hogan Michael E. ; Varma Rajender Singh, Optical and electrical methods and apparatus for molecule detection.
  122. Newman Arnold L. (Kensington MD), Optimized capacitive sensor for chemical analysis and measurement.
  123. Jagur Joseph (Rehovot ILX), Organometallic polymers, their preparation and compositions containing them.
  124. Dattagupta Nanibhushan (New Haven CT) Albarella James P. (Elkhart IN), Photochemical nucleic acid-labeling reagent having a polyalklamine spacer.
  125. Fodor Stephen P. A. (Palo Alto CA) Stryer Lubert (Stanford CA) Winkler James L. (Palo Alto CA) Holmes Christopher P. (Sunnyvale CA) Solas Dennis W. (San Francisco CA), Photolabile nucleoside and peptide protecting groups.
  126. Urdea Michael S. (Alamo CA) Horn Thomas (Berkeley CA), Photolabile reagents for incorporation into oligonucleotide chains.
  127. Kauer James C. (Kennett Square PA), Photoreactive benzoylphenylalanines and related peptides.
  128. Humphries Gillian M. K. (Los Altos CA) Parce John W. (Winston-Salem NC) McConnell Harden M. (Stanford CA), Photoresponsive redox detection and discrimination.
  129. Barany George (Falcon Heights MN) Albericio Fernando (Boston MA) Chang Jane (Vernon Hills IL) Zalipsky Samuel (Princeton NJ) Sole Nuria A. (Minneapolis MN), Polyethylene glycol derivatives for solid-phase applications.
  130. Holmes Christopher P. (Sunnyvale CA), Polymer reversal on solid surfaces.
  131. Schindler Melvin S. (Okemos MI) Holland John F. (Lansing MI), Positive selection sorting of cells.
  132. Mullis Kary B. (Kensington CA), Process for amplifying nucleic acid sequences.
  133. Mullis Kary B. (La Jolla CA) Erlich Henry A. (Oakland CA) Gelfand David H. (Oakland CA) Horn Glenn (Emeryville CA) Saiki Randall K. (Richmond CA), Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme.
  134. Caruthers Marvin H. (Boulder CO) Matteucci Mark D. (Boulder CO), Process for preparing polynucleotides.
  135. Caruthers Marvin H. (Boulder CO) Matteucci Mark D. (Boulder CO), Process for preparing polynucleotides.
  136. Frank Ronald (Wolfenbttel DEX) Heikens Wiebke (Braunschweig DEX), Process for the simultaneous synthesis of several oligonucleotides on a solid phase.
  137. Fusek Richard L. (Dayton OH), Production of high performance optical spatial filters.
  138. Stead Cecil V. (Manchester GB2) Lowe Christopher R. (Saffron Walden GB2), Protein adsorbent including a colored compound containing a quaternary ammonium especially amidinium or guanidimium cati.
  139. Urdea Michael S. (Alamo CA) Horn Thomas (Berkeley CA), Purification of synthetic oligomers.
  140. Landa Isaac J. (12109 Greenleaf Ave. Potomac MD 20854), Rapid and automatic fluorescence immunoassay analyzer for multiple micro-samples.
  141. Merril, Carl R., Rapid visualization system for gel electrophoresis.
  142. Nova Michael P. ; Senyei Andrew E., Remotely programmable matrices with memories.
  143. Patel Shailen S. (Santa Monica CA), Sample-scanning photometer.
  144. Rice Thomas K. (White Bear Lake MN), Sandwich immunoassay using piezoelectric oscillator.
  145. Clark Noel A. (Boulder CO) Douglas Kenneth (Boulder CO) Rothschild Kenneth J. (Newton MA), Self-assembled nanometer lithographic masks and templates and method for parallel fabrication of nanometer scale multi-d.
  146. Itakura Keiichi (Arcadia CA), Solid-phase synthesis of polynucleotides.
  147. Barrett Ronald W. (Sunnyvale CA) Pirrung Michael C. (Durham NC) Stryer Lubert (Stanford CA) Holmes Christopher P. (Sunnyvale CA) Sundberg Steven A. (San Francisco CA), Spatially-addressable immobilization of anti-ligands on surfaces.
  148. Krull Ulrich J. (Weston CAX) Thompson Michael (Mississauga CAX), Stabilized, lipid membrane-based device and method of analysis.
  149. Southern Edwin M. (Oxford GB3) Maskos Uwe (Oxford GB3), Support-bound oligonucleotides.
  150. Buendia Jean (Le Perreux Sur Marne FRX) Nierat Jeanine (Suresnes FRX), Supports and their use.
  151. Buendia Jean (Le Perreux sur Marne FRX) Nierat Jeanine (Suresnes FRX), Supports useful in solid phase synthesis of oligonucleotides.
  152. Fodor Stephen P. A. (Palo Alto CA) Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA) Stryer Lubert (Stanford CA), Synthesis and screening of immobilized oligonucleotide arrays.
  153. Kornreich Wayne D. (San Diego CA) Anderson Harry A. (San Diego CA) Porter John S. (Leucadia CA) Rivier Jean E. F. (La Jolla CA), Synthesis of N-substituted peptide amides.
  154. Steel Samuel (4401 W St. ; NW. Washington DC 20007), Synthesis of peptide analogs.
  155. Kaplan Jack H. (Bala Cynwyd PA) Ellis-Davis Graham C. R. (Philadelphia PA), Synthesis of photolabile chelators for multivalent cations.
  156. Still W. Clark ; Li Ge, Synthetic receptors, libraries and uses thereof.
  157. Rine Jasper ; Ashby Matthew, Systems for generating and analyzing stimulus-response output signal matrices.
  158. Southern Edwin,GBX ; Cummins William Jonathan,GBX, Tag reagent and assay method.
  159. Durley ; III Benton A. (Antioch IL) Defreese James D. (Wildwood IL) Merkh Carl W. (Lindenhurst IL), Test card for performing assays.
  160. Abu-Shumays Ahmad (Los Altos CA), Thermostatable flow cell for fluorescence measurements.
  161. Fuller William D. (San Diego CA) Cohen Michael P. (Salona Beach CA) Naider Fred R. (Staten Island NY) Goodman Murray (LaJolla CA), Urethane-protected amino acid-N-carboxyanhydrides.
  162. Schwartz Dennis E. (Redmond WA), Use of volume exclusion agents for the enhancement of in situ hybridization.
  163. Fodor Stephen P. A. (Palo Alto CA) Stryer Lubert (Stanford CA) Pirrung Michael C. (Durham NC) Read J. Leighton (Palo Alto CA), Very large scale immobilized polymer synthesis.
  164. Winkler James L. (Palo Alto CA) Fodor Stephen P. A. (Palo Alto CA) Buchko Christopher J. (Palo Alto CA) Ross Debra A. (Fremont CA) Aldwin Lois (San Mateo CA), Very large scale immobilized polymer synthesis using mechanically directed flow paths.
  165. Cozzette Stephen N. (Nepean CAX) Davis Graham (Plainsboro NJ) Itak Jeanne A. (North Brunswick NJ) Lauks Imants R. (Yardley PA) Mier Randall M. (Morrisville PA) Piznik Sylvia (Jackson NJ) Smit Nicolaa, Wholly microfabricated biosensors and process for the manufacture and use thereof.

이 특허를 인용한 특허 (89)

  1. Dickinson, Todd A.; Meade, Shawn; Barnard, Steven M.; Czarnik, Anthony W.; Bierle, James; Kermani, Bahram G.; Chee, Mark S., Array compositions for improved signal detection.
  2. El Gamal, Abbas; Eltoukhy, Helmy; Salama, Khaled, Biological analysis arrangement and approach therefor.
  3. El Gamal, Abbas; Eltoukhy, Helmy; Salama, Khaled, Biological analysis arrangement and approach therefor.
  4. El Gamal, Abbas; Eltoukhy, Helmy; Salama, Khaled, Biological analysis arrangement and approach therefor.
  5. El Gamal, Abbas; Eltoukhy, Helmy; Salama, Khaled, Biological analysis arrangement and approach therefor.
  6. Moon, John A.; Putnam, Martin A.; Kersey, Alan D.; Fournier, David; Pinto, Joseph, Composition including an item and an encoded optical substrate and a method for identifying an item.
  7. Gunderson, Kevin; Stuelpnagel, John R.; Chee, Mark S., Detection of nucleic acid reactions on bead arrays.
  8. Gunderson, Kevin; Stuelpnagel, John R.; Chee, Mark S.; Fan, Jian-Bing, Detection of nucleic acid reactions on bead arrays.
  9. Gunderson, Kevin; Stuelpnagel, John R.; Chee, Mark S.; Fan, Jian-Bing, Detection of nucleic acid reactions on bead arrays.
  10. Moon,John A.; Putnam,Martin A., Diffraction grating-based encoded micro-particles for multiplexed experiments.
  11. Moon,John A.; Putnam,Martin A., Diffraction grating-based encoded particle.
  12. Fu, Glenn K.; Fodor, Stephen P. A., Digital counting of individual molecules by stochastic attachment of diverse label-tags.
  13. Fodor, Stephen P. A.; Fu, Glenn K., Digital counting of individual molecules by stochastic attachment of diverse labels.
  14. Fodor, Stephen P. A.; Fu, Glenn K., Digital counting of individual molecules by stochastic attachment of diverse labels.
  15. Fodor, Stephen P. A.; Fu, Glenn K., Digital counting of individual molecules by stochastic attachment of diverse labels.
  16. Fodor, Stephen P. A.; Fu, Glenn K., Digital counting of individual molecules by stochastic attachment of diverse labels.
  17. Fodor, Stephen P. A.; Fu, Glenn K., Digital counting of individual molecules by stochastic attachment of diverse labels.
  18. Fodor, Stephen P. A.; Fu, Glenn K., Digital counting of individual molecules by stochastic attachment of diverse labels.
  19. Fodor, Stephen P. A.; Fu, Glenn K., Digital counting of individual molecules by stochastic attachment of diverse labels.
  20. Fodor, Stephen P. A.; Fu, Glenn K., Digital counting of individual molecules by stochastic attachment of diverse labels.
  21. Fodor, Stephen P. A.; Fu, Glenn K., Digital counting of individual molecules by stochastic attachment of diverse labels.
  22. Kersey, Alan D.; Moon, John A.; Putnam, Martin A., Elongated microparticles having an optically detectable code configured to at least one of reflect or filter light.
  23. Kersey, Alan D.; Moon, John A.; Putnam, Martin A., Encoded microparticles and a method for fabricating.
  24. Moon, John A.; Putnam, Martin A., Encoded particle having a grating with variations in the refractive index.
  25. Shum, Eleen, Error correction in amplification of samples.
  26. Brenner,Sydney, Genetic analysis by sequence-specific sorting.
  27. Brenner,Sydney, Genetic analysis by sequence-specific sorting.
  28. Kersey, Alan; Moon, John A.; Putnam, Martin A., Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same.
  29. Moon, John A.; Kersey, Alan D.; Putnam, Martin A.; Li, Tuo, Hybrid random bead/chip based microarray.
  30. Moon,John; Kersey,Alan D.; Putnam,Martin A.; Li,Tuo, Hybrid random bead/chip based microarray.
  31. Casbon, James; Brenner, Sydney; Osborne, Robert; Lichtenstein, Conrad; Claas, Andreas, Increased confidence of allele calls with molecular counting.
  32. Casbon, James; Brenner, Sydney; Osborne, Robert; Lichtenstein, Conrad; Claas, Andreas, Increasing confidence of allele calls with molecular counting.
  33. Kersey,Alan D.; Moon,John A.; Putnam,Martin A., Lithographically fabricated holographic optical identification element.
  34. Fan, Christina; Fodor, Stephen P. A.; Fu, Glenn; Facer, Geoffrey Richard; Wilhelmy, Julie, Massively Parallel single cell analysis.
  35. Fan, Christina; Fodor, Stephen P. A.; Fu, Glenn; Facer, Geoffrey Richard; Wilhelmy, Julie, Massively parallel single cell analysis.
  36. Fan, Christina; Fodor, Stephen P. A.; Fu, Glenn; Facer, Geoffrey Richard; Wilhelmy, Julie, Massively parallel single cell analysis.
  37. Fan, Christina; Fodor, Stephen P. A.; Fu, Glenn; Facer, Geoffrey Richard; Wilhelmy, Julie, Massively parallel single cell analysis.
  38. Fan, Christina; Fodor, Stephen P. A.; Fu, Glenn; Facer, Geoffrey Richard; Wilhelmy, Julie, Massively parallel single cell analysis.
  39. Fan, Christina; Fodor, Stephen P. A.; Fu, Glenn; Facer, Geoffrey Richard; Wilhelmy, Julie, Massively parallel single cell analysis.
  40. Fan, Christina; Fodor, Stephen P. A.; Fu, Glenn; Facer, Geoffrey Richard; Wilhelmy, Julie, Massively parallel single cell analysis.
  41. Fan, Christina; Fodor, Stephen P. A.; Fu, Glenn; Facer, Geoffrey Richard; Wilhelmy, Julie, Massively parallel single cell analysis.
  42. Moon,John; Putnam,Martin A.; Li,Tuo; Traynor,Joseph, Method and apparatus for aligning microbeads in order to interrogate the same.
  43. Moon, John A.; Putnam, Martin A.; Kersey, Alan; Fournier, David; Pinto, Joseph, Method and apparatus for drug product tracking using encoded optical identification elements.
  44. Moon,John A.; Putnam,Martin A.; Kersey,Alan D.; Li,Tuo; Dunphy,James; Didden,F. Kevin, Method and apparatus for labeling using diffraction grating-based encoded optical identification elements.
  45. Moon, John A.; Putnam, Martin A.; Kersey, Alan D.; Szczepanek, Paul, Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction.
  46. Casbon, James; Brenner, Sydney; Osborne, Robert; Lichtenstein, Conrad; Claas, Andreas, Method for accurately counting starting molecules.
  47. Osborne, Robert; Casbon, James; Claas, Andreas; Mikawa, Gi; Musgrave-Brown, Esther, Method for attaching a counter sequence to a nucleic acid sample.
  48. Casbon, James; Brenner, Sydney; Osborne, Robert; Lichtenstein, Conrad; Claas, Andreas, Method for preparing a counter-tagged population of nucleic acid molecules.
  49. Casbon, James; Brenner, Sydney; Osborne, Robert; Lichtenstein, Conrad; Claas, Andreas, Method of adding a DBR by primer extension.
  50. Putnam,Martin A.; Moon,John; Szczepanek,Paul S.; Li,Tuo; Rauseo,Anthony; Traynor,Joseph, Method of manufacturing of a diffraction grating-based optical identification element.
  51. Casbon, James; Brenner, Sydney; Osborne, Robert; Lichtenstein, Conrad; Claas, Andreas, Method of tagging using a split DBR.
  52. Eltoukhy, Helmy; Talasaz, AmirAli, Methods and systems for detecting genetic variants.
  53. Fu, Glenn; Rudoff, Roger; Stern, David; Wu, George T.; Fodor, Stephen P. A.; Facer, Geoffrey, Methods and systems for digitally counting features on arrays.
  54. Fu, Glenn; Rudoff, Roger; Stern, David; Wu, George T.; Fodor, Stephen P. A.; Facer, Geoffrey, Methods and systems for digitally counting features on arrays.
  55. Zhou, Fang X.; Schweitzer, Barry, Methods for conducting assays for enzyme activity on protein microarrays.
  56. Dickinson, Todd; Coblentz, Kenneth D.; Carlson, Edward, Methods of detecting targets on an array.
  57. Moon, John A.; Kersey, Alan D.; Putnam, Martin A.; Li, Tuo, Methods of identifying an analyte and nucleic acid analysis.
  58. Moon, John A.; Kersey, Alan D.; Putnam, Martin A.; Li, Tuo, Methods of identifying analytes and using encoded particles.
  59. Hoeffler, James P.; Fernandez, Joseph M.; Nasoff, Marc S., Microarray and uses therefor.
  60. McCormick,Mark; Stengele,Klaus Peter; Barrett,Gary; Green,Roland, Microarray with hydrophobic barriers.
  61. Hoeffler, James P.; Fernandez, Joseph M.; Nasoff, Marc S., Microarrays and uses therefor.
  62. Hoeffler, James; Fernandez, Joseph; Nasoff, Marc, Microarrays and uses therefor.
  63. Brenner, Sydney; Macevicz, Stephen C., Molecular counting.
  64. Oliphant, Arnold; Stuelpnagel, John R.; Chee, Mark S.; Butler, Scott L.; Fan, Jian Bing; Shen, Min Jui Richard, Multiplex nucleic acid reactions.
  65. Oliphant, Arnold; Stuelpnagel, John R.; Chee, Mark S.; Butler, Scott L.; Fan, Jian-Bing; Shen, Min-Jui Richard, Multiplex nucleic acid reactions.
  66. Oliphant, Arnold; Stuelpnagel, John R.; Chee, Mark S.; Butler, Scott L.; Fan, Jian-Bing; Shen, Min-Jui Richard, Multiplex nucleic acid reactions.
  67. Oliphant, Arnold; Stuelpnagel, John R.; Chee, Mark S.; Butler, Scott L.; Fan, Jian-Bing; Shen, Min-Jui Richard, Multiplex nucleic acid reactions.
  68. Shen, Min-Jui Richard; Oliphant, Arnold; Butler, Scott L.; Stuelpnagel, John R.; Chee, Mark S.; Kuhn, Kenneth M.; Fan, Jian-Bing, Multiplex nucleic acid reactions.
  69. Brenner,Sydney, Multiplexed analytical platform.
  70. Fan, Jian-Bing, Multiplexed methylation detection methods.
  71. Putnam, Martin A.; Moon, John A., Optical identification element having a non-waveguide substrate.
  72. Putnam,Martin A.; Moon,John A., Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein.
  73. Noto, John; Kerr, Robert B.; Zhang, Hailiang; Marder, William Z.; Warren, Anthony C., Optical multiplexer and cross-switch using etched liquid crystal Fabry-Perot etalons.
  74. Moon,John A.; Fournier,David R.; Putnam,Martin A.; Kersey,Alan D.; Li,Tuo, Optical reader for diffraction grating-based encoded optical identification elements.
  75. Putnam, Martin A.; Lemoine, Richard L., Optical reader for reading encoded microparticles.
  76. Moon, John A.; Fournier, David R.; Putnam, Martin A.; Kersey, Alan D; Li, Tuo, Optical reader system for substrates having an optically readable code.
  77. Moon, John A.; Fournier, David R., Optical scanner with improved scan time.
  78. Moon, John A.; Putnam, Martin A., Optical system and method for reading encoded microbeads.
  79. Moon, John A.; Putnam, Martin A., Optical system and method for reading encoded microbeads.
  80. Snyder, Michael; Reed, Mark; Zhu, Heng; Klemic, James Frank, Protein chips for high throughput screening of protein activity.
  81. Kersey, Alan; Moon, John A., Scanner having spatial light modulator.
  82. Fodor, Stephen P. A.; Fan, Christina; Fu, Glenn; Facer, Geoffrey, Spatially addressable molecular barcoding.
  83. Fodor, Stephen P. A.; Fan, Christina; Fu, Glenn; Facer, Geoffrey, Spatially addressable molecular barcoding.
  84. Talasaz, AmirAli, Systems and methods to detect rare mutations and copy number variation.
  85. Talasaz, AmirAli, Systems and methods to detect rare mutations and copy number variation.
  86. Talasaz, AmirAli, Systems and methods to detect rare mutations and copy number variation.
  87. Talasaz, AmirAli, Systems and methods to detect rare mutations and copy number variation.
  88. Talasaz, AmirAli, Systems and methods to detect rare mutations and copy number variation.
  89. Talasaz, AmirAli; Eltoukhy, Helmy, Systems and methods to detect rare mutations and copy number variation.
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