초록

Methods for extracting DNA from a biological sample that result in a higher yield of target DNA than conventional methods. More particularly, methods for extracting DNA include exposing the biological sample to inhibitors of DNA degradation.

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1. A method for preserving the integrity of DNA in a stool sample, the method comprising: exposing the stool sample to EDTA in a range from about 0.250 gram EDTA per gram of stool to about 0.782 gram EDTA per gram of stool to preserve the integrity of DNA. 2. The method of claim 1 further compr

1. A method for preserving the integrity of DNA in a stool sample, the method comprising: exposing the stool sample to EDTA in a range from about 0.250 gram EDTA per gram of stool to about 0.782 gram EDTA per gram of stool to preserve the integrity of DNA. 2. The method of claim 1 further comprising a step of extracting a target DNA. 3. The method of claim 2 wherein the step of extracting comprises a phenol-chloroform extraction. 4. A method for preserving the integrity of DNA in a sample containing exfoliated cells, the method comprising: exposing the sample to EDTA in a range from 0.250 gram EDTA per gram of sample to about 0.782 gram EDTA per gram of sample to preserve the integrity of DNA. 5. The method of claim 4 wherein the sample is obtained from stool. 6. The method of claim 4 further comprising extracting a target DNA. 7. The method of claim 6 wherein the step of extracting comprises a phenol-chloroform extraction. 8. The method of claim 1 comprising exposing the sample to EDTA in a range from about 0.250 gram EDTA per gram of stool to about 0.521 gram EDTA per gram of stool to preserve the integrity of DNA. 9. The method of claim 1 comprising exposing the sample to about 0.391 gram EDTA per gram of stool to preserve the integrity of DNA. 10. The method of claim 4 comprising exposing the sample to EDTA in a range from about 0.250 gram EDTA per gram of sample to about 0.521 gram EDTA per gram of sample to preserve the integrity of DNA. 11. The method of claim 4 comprising exposing the sample to about 0.391 gram EDTA per gram of sample to preserve the integrity of DNA.