초록 ▼

A medical device of metallic or non-metallic material coated with a combination of antiseptics and a method for coating such an implant with a combination of antiseptics is provided. Different combinations of antiseptics can be used for different types of medical devices depending on the spectrum of

A medical device of metallic or non-metallic material coated with a combination of antiseptics and a method for coating such an implant with a combination of antiseptics is provided. Different combinations of antiseptics can be used for different types of medical devices depending on the spectrum of organisms that cause the infections related to each device. The combination of different antiseptics has a synergistic effect against certain bacteria and fungi. The combination of antiseptic can be applied to the surface of a metallic device by dissolving the combination of antiseptics and a polymeric sticking agent in an acid solution to form an antiseptic solution, and applying the antiseptic solution, in an effective concentration to inhibit the growth of bacterial and fungal organisms, to at least a portion of the surfaces of the medical device. The antiseptic combination can be applied to the surface of and impregnate the material of a non-metallic implant by forming an antiseptic composition by dissolving the combination of antiseptics in an organic solvent and adding a penetrating agent to the composition, and applying the antiseptic composition to at least a portion of the medical implant under conditions where the antiseptic composition permeates the material of the medical implant.

대표청구항 ▼

1. An implantable medical device comprising: a non-metallic medical device having at least one surface; an antiseptic composition layer coating the at least one surface of the medical device, the antiseptic composition comprising a mixture of the combination of antiseptics, methanol, and butyl a

1. An implantable medical device comprising: a non-metallic medical device having at least one surface; an antiseptic composition layer coating the at least one surface of the medical device, the antiseptic composition comprising a mixture of the combination of antiseptics, methanol, and butyl acetate, said antiseptic composition in an effective concentration to inhibit the growth of bacterial and fungal organisms; and wherein said antiseptic composition penetrates the at least one surface of the non-metallic medical device. 2. The medical device of claim 1, wherein the combination of antiseptics is selected from the group of mixtures consisting of methylisothiazolone and thymol; chlorhexidine, methylisothiazolone and thymol; chlorhexidine, methylisothiazolone, and α-terpineol; chloroxylenol and thymol; chlorhexidine and cetylpyridinium chloride; and chlorhexidine and chloroxylenol. 3. The medical device of claim 1 wherein the combination of antiseptics comprises a mixture of thymol and either chloroxylenol or methylisothiazolone. 4. The medical device of claim 1 wherein the combination of antiseptics comprises a mixture of chlorhexidine, methylisothiazolone and α-terpineol. 5. The medical device according to claim 4, further comprising a mixture of glacial acetic acid and formic acid.