초록 ▼

A device and method are provided for sealing a puncture in a body vessel. The device has an elongated body having a proximal end and a distal end sized to be positioned within a lumen of the body vessel; at least one closure composition precursor lumen within the elongated body having a entrance por

A device and method are provided for sealing a puncture in a body vessel. The device has an elongated body having a proximal end and a distal end sized to be positioned within a lumen of the body vessel; at least one closure composition precursor lumen within the elongated body having a entrance port adjacent the proximal end of the elongated body through which one or more fluent closure composition precursors can be delivered into the closure composition precursor lumen and an exit port adjacent the distal end of the elongated body through which the one or more fluent closure composition precursors can be delivered outside the vessel adjacent the vessel puncture; and a microwave antenna for delivering microwave energy adjacent the distal end of the elongated body to the fluent closure compound precursor. The microwave antenna according to this embodiment is preferably incorporated onto the elongated body adjacent the body distal end. Alternatively, the device can include a guidewire lumen and a guidewire which includes a microwave antenna.

대표청구항 ▼

1. An assembly for introducing a closure material to seal a vessel puncture site, the closure material comprising a mixture of a first and second fluid composition which, upon mixing, react to form a nonfluent closure composition, the assembly comprising a catheter for passage through a tissue pu

1. An assembly for introducing a closure material to seal a vessel puncture site, the closure material comprising a mixture of a first and second fluid composition which, upon mixing, react to form a nonfluent closure composition, the assembly comprising a catheter for passage through a tissue puncture and having a distal end, at least one fluid delivery port adjacent the catheter distal end to occupy a position adjacent the vessel puncture site, and a lumen in the catheter in fluid communication with the fluid delivery port, one or more dispensers in fluid communication with the catheter lumen for dispensing the first and second fluid compositions in the catheter lumen, and an actuator for causing the first and second fluid compositions to be dispensed from the one or more dispensers mixed by flowing the first and second fluid compositions through a static mixer within the lumen and dispensed from the fluid delivery port as a fluid mixture that reacts in situ to form the nonfluent closure composition adjacent the vessel puncture site, wherein the catheter is sized to block flow of the fluid mixture from the fluid delivery port into a substantial part of the tissue puncture, whereby a localized in situ closure forms adjacent the vessel puncture site to seal the vessel puncture site. 2. An assembly as in claim 1, wherein the static mixer is incorporated into the catheter. 3. An assembly as in claim 1, wherein the static mixer is a cartridge. 4. A method for sealing a vascular puncture site comprising the steps of introducing a catheter through a tissue puncture, the catheter including a distal end and at least one fluid delivery port adjacent the distal end to be positioned adjacent the vessel puncture site, the catheter being sized to occupy substantially all the tissue puncture, providing first and second fluid compositions which, upon mixing, react to form a nonfluent closure composition, mixing the first and second fluid compositions by flowing the components through a lumen containing a static mixer in the catheter, the lumen communicating with the fluid delivery port, and dispensing the first and second fluid compositions from the fluid delivery port as a fluid mixture that reacts in situ to form the nonfluent closure composition adjacent the vessel puncture site, the size of the catheter blocking flow of the fluid mixture from the fluid delivery port into a substantial part of the tissue puncture, whereby a localized in situ closure forms adjacent the vessel puncture site seal the vessel puncture site. 5. A method as in claim 4 wherein the static mixer is incorporated into the catheter. 6. A method as in claim 4, wherein the static mixer is a cartridge.