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Transdermal administration of oxybutynin using hydroxide-releasing agents as permeation enhancers 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-013/00
  • A61F-013/02
  • A61L-015/00
  • A61L-015/16
출원번호 US-0737828 (2000-12-14)
발명자 / 주소
  • Hsu, Tsung-Min
  • Luo, Eric C.
출원인 / 주소
  • Dermatrends, Inc.
대리인 / 주소
    Reed, Dianne E.Eberle, Shelley P.Reed & Eberle LLP
인용정보 피인용 횟수 : 11  인용 특허 : 36

초록 ▼

A method is provided for increasing the permeability of skin or mucosal tissue to transdermally administered oxybutynin. The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase the flux of the drug through a body surface while minimizing the lik

대표청구항 ▼

A method is provided for increasing the permeability of skin or mucosal tissue to transdermally administered oxybutynin. The method involves use of a specified amount of a hydroxide-releasing agent, the amount optimized to increase the flux of the drug through a body surface while minimizing the lik

이 특허에 인용된 특허 (36)

  1. Mantelle Juan A. (Miami FL), Compositions and methods for topical administration of pharmaceutically active agents.
    상세보기
  2. Oloff Horst (Berlin DEX) Tack Johannes-Wilhelm (Berlin DEX) Windt Fred (Berlin DEX) Zimmermann Ingfried (Berlin DEX), Device for transdermal administration of active medicinal agents.
    상세보기
  3. Guittard George V. (Cupertino CA) Jao Francisco (San Jose CA) Marks Susan M. (San Jose CA) Kidney David J. (Sunnyvale CA) Gumucio Fernando (Santa Clara CA), Dosage form comprising oxybutynin.
    상세보기
  4. Therriault Donald J. (York PA) Rodgers Kenneth W. (York PA), Drug flux enhancer-tolerant pressure sensitive adhesive composition.
    상세보기
  5. Ron Eyal S. ; Bromberg Lev ; Temchenko Marina, End modified thermal responsive hydrogels.
    상세보기
  6. Cody Sharon L. ; Fegley Richard D. ; Hoy Michael R., Enhanced delivery of topical compositions containing flurbiprofen.
    상세보기
  7. Scholz Matthew T. ; Asmus Robert A. ; Hedenstrom John C., Hydroalcoholic compositions for transdermal penetration of pharmaceutical agents.
    상세보기
  8. Ikeda Yasuo,JPX ; Okuyama Hirohisa,JPX ; Ishigaki Kenji,JPX ; Kasai Shuichi,JPX ; Imamori Katsumi,JPX, Hydrophilic adhesive masses.
    상세보기
  9. Yamanaka Akihito,JPX ; Kinoshita Takashi,JPX ; Sunami Masaki,JPX, Medicated plaster containing basic physiologically active agents and/or salts thereof.
    상세보기
  10. Foldvari Marianna,CAX, Method for preparing biphasic multilamellar lipid vesicles.
    상세보기
  11. Curtis Ernest S. ; Kalafsky Robert ; Kaplan Elinor R., Method of treating the skin with organic acids in anhydrous microsphere delivery systems.
    상세보기
  12. Parab Prakash ; Yu Cheng Der Tony ; Patel Bhiku, Methods and compositions for enhancing skin permeation of drugs using permeation enhancers, when drugs and/or permeation enhancers are unstable in combination during long-term storage.
    상세보기
  13. Aberg Gunnar (Westborough MA) McCullough John R. (Worcester MA), Methods and compositions for treating urinary incontinence using optically pure (S)-oxybutynin.
    상세보기
  14. Lee Vincent H. (Monterey Park CA) Yen Wan-Ching (Columbus OH), Methods and compositions to enhance epithelial drug transport.
    상세보기
  15. Yamazaki Chika,JPX ; Sato Tadao,JPX ; Nagano Tatsuo,JPX, Monohydrates of aminobenzenesulfonic acid derivatives and method for preparing thereof.
    상세보기
  16. Ptchelintsev Dmitri ; Scancarella Neil ; Kalafsky Robert, Oxa acids and related compounds for treating skin conditions.
    상세보기
  17. Ptchelintsev Dmitri ; Scancarella Neil ; Kalafsky Robert, Oxa diacids and related compounds for treating skin conditions.
    상세보기
  18. Gale Robert M. (Los Altos CA) Lee Eun Soo (Redwood City CA) Taskovich Lina T. (Palo Alto CA) Burkoth Terry L. (Palo Alto CA), Oxybutynin transdermal device having decreased delamination.
    상세보기
  19. Wolter Karin (Melsbach DEX) Mller Walter (Neuwied DEX) Simon Gnter (Hillesheim DEX) Nalbach Christa (Leutesdorf DEX) Hoffmann Hans-Rainer (Neuwied DEX), Patch for transdermal administration of volatile pharmaceutically active ingredients of chemically basic nature and a pr.
    상세보기
  20. Lerner E. Itzhak,ILX ; Rosenberger Vered,ILX ; Flashner Moshe,ILX, Pharmaceutical oral patch for controlled release of pharmaceutical agents in the oral cavity.
    상세보기
  21. Venkateshwaran Srinivasan ; Fikstad David ; Ebert Charles D., Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents.
    상세보기
  22. Scarborough Robert M. ; Zhu Bing-Yan ; Su Ting, Selective factor Xa inhibitors.
    상세보기
  23. Miranda Jesus (Miami FL) Sablotsky Steven (Miami FL), Solubility parameter based drug delivery system and method for altering drug saturation concentration.
    상세보기
  24. Perricone Nicholas V., Topical administration of catecholamines and related compounds to subcutaneous muscle tissue using percutaneous penetra.
    상세보기
  25. Durif Franck (Durtol FRX) El-Rashidy Ragab (Deerfield IL), Transdermal administration of apomorphine.
    상세보기
  26. Durif Franck,FRX ; El-Rashidy Ragab, Transdermal administration of apomorphine.
    상세보기
  27. Lee Eun S. (Redwood City CA) Nedberge Diane E. (Los Altos CA) Yum Su I. (Los Altos CA), Transdermal administration of oxybutynin.
    상세보기
  28. Lhila Ramesh (South Windsor CT) Ganslaw Stuart (Simsbury CT) Serra Eleanor (West Springfield MA), Transdermal delivery of appetite suppressant drug.
    상세보기
  29. Lee Eun S. (Redwood City CA) Yum Su I. (Los Altos CA), Transdermal drug delivery device.
    상세보기
  30. Song Suk-Zu (Flanders NJ) Mehta Surendra C. (Randolph NJ) Rashidbaigi Zahra A. (Nutley NJ) Nesbitt Russell U. (Somerville NJ) Fawzi Mahdi B. (Flanders NJ), Transdermal matrix system.
    상세보기
  31. Therriault Donald J. ; Zajaczkowski Michael J. ; Stutzman Barbara A., Transdermal pressure sensitive adhesive drug delivery system.
    상세보기
  32. Gupte Arun R. (Ingelheim am Rhein DEX) Rohr Uwe (Gau Algesheim DEX) Zierenberg Bernd (Bingen DEX), Transdermal system for the administration of pharmacological compounds under pH-controlled conditions.
    상세보기
  33. Aberg A. K. Gunnar, Treating urinary incontinence with (R)-desethyloxybutynin and (R)-oxybutynin.
    상세보기
  34. Majeti Satyanarayana (Cincinnati OH), Treatment of nicotine craving and/or smoking withdrawal symptoms.
    상세보기
  35. Sawanishi Hiroyuki (Kanazawa JPX) Ito Yasuo (Katsuyama JPX) Kato Hideo (Fukui JPX) Koshinaka Eiichi (Katsuyama JPX) Ogawa Nobuo (Katsuyama JPX) Morikawa Kouji (Katsuyama JPX), Tricyclic compounds and method for treating allergic diseases.
    상세보기
  36. Hsu Tsung-Min ; Chen Tung Fen, Two-phase matrix for sustained release drug delivery device.
    상세보기

이 특허를 인용한 특허 (11)

  1. Sanders,Steven W.; Ebert,Charles D., Compositions and methods for minimizing adverse drug experiences associated with oxybutynin therapy.
    상세보기
  2. Sanders,Steven W.; Ebert,Charles D., Compositions and methods for minimizing adverse drug experiences associated with oxybutynin therapy.
    상세보기
  3. Sanders,Steven W.; Ebert,Charles D., Compositions and methods for minimizing adverse drug experiences associated with oxybutynin therapy.
    상세보기
  4. Sanders,Steven W.; Ebert,Charles D., Compositions and methods for minimizing adverse drug experiences associated with oxybutynin therapy.
    상세보기
  5. Ebert,Charles D.; Sanders,Steven W., Compositions and methods for transdermal oxybutynin therapy.
    상세보기
  6. Ebert,Charles D.; Sanders,Steven W., Compositions and methods for transdermal oxybutynin therapy.
    상세보기
  7. Bartels, Jennifer, Methods and compositions for oxygenation of skin to treat skin disorders.
    상세보기
  8. Zinger, Menni Menashe, Methods for the treatment of hyperhidrosis.
    상세보기
  9. Chase, Thomas N.; Clarence-Smith, Kathleen E., Oxybutynin-xanomeline transdermal therapeutic system combinations.
    상세보기
  10. Bartels, Jennifer, Permeable mixtures, methods and compositions for the skin.
    상세보기
  11. Ebert, Charles D.; Sanders, Steven W., Unoccluded topical oxybutynin gel composition and methods for transdermal oxybutynin therapy.
    상세보기

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