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Disclosed is a method of fuelling an internal combustion engine by injection of a fuel-gas mixture to a combustion chamber of the engine comprising delivering a metered quantity of fuel from a fuel metering means to a delivery injector operation, the delivery injector being in communication with bot

Disclosed is a method of fuelling an internal combustion engine by injection of a fuel-gas mixture to a combustion chamber of the engine comprising delivering a metered quantity of fuel from a fuel metering means to a delivery injector operation, the delivery injector being in communication with both the combustion chamber and a supply of pressurized gas for effecting delivery of the metered quantity of fuel to the combustion chamber, wherein at least one of the fuel metering means and the delivery injector are controlled in multiple events and a predetermined fuel distribution in the combustion chamber at ignition during that cycle of engine operation.

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Disclosed is a method of fuelling an internal combustion engine by injection of a fuel-gas mixture to a combustion chamber of the engine comprising delivering a metered quantity of fuel from a fuel metering means to a delivery injector operation, the delivery injector being in communication with bot

Disclosed is a method of fuelling an internal combustion engine by injection of a fuel-gas mixture to a combustion chamber of the engine comprising delivering a metered quantity of fuel from a fuel metering means to a delivery injector operation, the delivery injector being in communication with both the combustion chamber and a supply of pressurized gas for effecting delivery of the metered quantity of fuel to the combustion chamber, wherein at least one of the fuel metering means and the delivery injector are controlled in multiple events and a predetermined fuel distribution in the combustion chamber at ignition during that cycle of engine operation. pha, 25-dihydroxyvitamin D3 involves extracellular, but not intracellular, calcium," J. Cell. Physiol., 142: 434-439 (1990). Kanatani, M., et al., "Effect of elevated extracellular calcium on the proliferation of osteoblastic MC3T3-E1 cells: its direct and indirect effects via monocytes," Biochem. Biophys. Res. Commun., 181: 1425-1430 (1991). Kanatani, M., et al., "High extracellular Calcium Inhibits Osteoclast-like Cell formation by Directly Acting on the Calcium-Sensing Receptor Existing in Osteoclast Precursor Cells," Biochem. Biophys. Res. Commun., 261: 144-148 (1999). Lajeunesse, D., et al., "Regulation of osteocalcin secretion by human primary bone cells and by the human osteosarcoma cell line MG-63," Bone Min