초록 ▼

Crude drug extracts containing soluble silicon compounds as an effective component are obtained by subjecting a crude drug to extraction with water or an aqueous solvent, preferably at an alkaline pH. The crude drugs subjected to extraction to obtain the extracts may be derived from animals, plants,

Crude drug extracts containing soluble silicon compounds as an effective component are obtained by subjecting a crude drug to extraction with water or an aqueous solvent, preferably at an alkaline pH. The crude drugs subjected to extraction to obtain the extracts may be derived from animals, plants, etc. The quality of the crude drug extract can be standardized using the soluble silicon compounds as an index. The soluble silicon compounds exhibit inhibitory action towards the production of plasma kallikrein. The amount of soluble silicon compounds in the dry extract may be used as an index whereby the quality of various crude drugs can be standardized which contributes to providing crude drug extracts having a stable or consistent quality. Consequently, the present invention greatly contributes to the appropriate standardization of pharmaceuticals.

대표청구항 ▼

1. An extract from a plant or a fungus, wherein the extract comprises at least about 0.05 mg of at least one soluble silicon compound calculated as silicon per gram of dry extract, as an effective component, wherein the extract exhibits inhibitory action against the production of plasma kallikrein,

1. An extract from a plant or a fungus, wherein the extract comprises at least about 0.05 mg of at least one soluble silicon compound calculated as silicon per gram of dry extract, as an effective component, wherein the extract exhibits inhibitory action against the production of plasma kallikrein, said extract being obtained by extraction with water or an aqueous solvent, wherein the pH of said water or aqueous solvent is 8.5 to 10.5, and wherein said plant or fungus comprises at least one member selected from the group consisting of tanjin (Salvia miltiorrhiza radix), shireishi (Ganoderma lucidum), scouring rush (Equisetum hiemale), Chinese gutta percha, chorei (polyporus sclerotiumt bukuryo (poria selerotium), and pueraria root. 2. An extract as claimed in claim 1 which is a) positive to terpenes, steroids or saccharides by anisaldehyde analysis, b) positive to color reaction with antimony trichloride, and c) positive to color reaction with ninhydrin. 3. An extract as claimed in claim 1 which is negative to pentoses by orcinol-ferric chloride analysis. 4. An extract as claimed in claim 1 wherein said extract is obtained by extraction with water or an aqueous solvent to obtain an extract solution and the extract solution is dried to obtain an extract in powder form. 5. An extract as claimed in claim 1 wherein said plant or fungus is shireishi (Ganoderma lucidum). 6. An extract as claimed in claim 1 which exhibits an analgesic, anti-inflammatory or anti-allergic action. 7. An extract as claimed in claim 1 wherein said plant or fungus is at least one member selected from the group consisting of tanjin (Salvia miltiorrhiza radix), scouring rush (Equisetum hiemale), Chinese gutta percha, chorei (polyporus sclerotium), bukuryo (poria sclerotium), and pueraria root. 8. An extract as claimed in claim 1 wherein said plant or fungus is tanjin (Salvia miltiorrhiza radix).