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Drug releasing biodegradable fiber implant 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61F-002/02
  • A61K-047/30
출원번호 US-0632457 (2000-08-04)
발명자 / 주소
  • Nelson, Kevin D.
  • Romero-Sanchez, Andres A.
  • Smith, George M.
  • Alikacem, Nadir
  • Radulescu, Delia
  • Waggoner, Paula
  • Hu, Zhibing
출원인 / 주소
  • Board of Regents, The University of Texas System
대리인 / 주소
    Jenkens & Gilchrist, P.C.
인용정보 피인용 횟수 : 523  인용 특허 : 8

초록 ▼

The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise biodegradable polymer fibers capable of the controlled delivery of therapeutic agents. The spatial and temporal dis

대표청구항 ▼

The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise biodegradable polymer fibers capable of the controlled delivery of therapeutic agents. The spatial and temporal dis

이 특허에 인용된 특허 (8)

  1. Greidanus Pieter J. (Bergschenhoek NLX) Feijen Jan (Hengelo NLX) Eenink Marinus J. D. (Enschede NLX) Rieke Johannes C. (Delft NLX) Olijslager Jan (Delft NLX) Albers Jan H. M. (Rijswijk NLX), Biodegradable polymer substrates loaded with active substance suitable for the controlled release of the active substanc.
    상세보기
  2. Collombel Christian (Lyon FRX) Damour Odile (Saint Genis Laval FRX) Gagnieu Christian (Lyon FRX) Poinsignon Frederique (Lyon FRX) Echinard Christian (Gemenos FRX) Marichy Jacques (Lyon FRX), Biomaterials with a base of mixtures of collagen, chitosan and glycosaminoglycans, process for preparing them and their.
    상세보기
  3. Sinclair Richard G. (Columbus OH) Lipinsky Edward S. (Worthington OH) Browning James D. (Columbus OH) Bigg Donald (Columbus OH) Rogers Thomas A. (Golden CO), End use applications of biodegradable polymers.
    상세보기
  4. Vacanti Joseph P. (Winchester MA) Freeman Michael R. (Boston MA), Genitourinary cell-matrix structure for implantation into a human and a method of making.
    상세보기
  5. Kaplan Aaron V. (3477 Thomas Dr. Palo Alto CA 94303), Method and device for treating and enlarging body lumens.
    상세보기
  6. Pittalis Francesco (Rome ITX) Bartoli Francesco (Rome ITX) Giovannoni Guido (S. Giuliano Milanese ITX), Process for the preparation of chitosan fibers.
    상세보기
  7. Li Shu-Tung (Oakland NJ) Stone Kevin R. (Mill Valley CA), Prosthetic ligaments.
    상세보기
  8. Jernberg Gary R. (99 Navaho Ave. Suite 102 Mankato MN 56001), Surgical implant and method for controlled release of chemotherapeutic agents.
    상세보기

이 특허를 인용한 특허 (523)

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  278. Aronhalt, Taylor W.; Vendely, Michael J.; Shelton, IV, Frederick E.; Schellin, Emily A.; Reynolds, II, Donald L., Releasable tissue thickness compensator and fastener cartridge having the same.
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  279. Shelton, IV, Frederick E.; Baxter, III, Chester O., Replaceable clip cartridge for a clip applier.
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  280. Baxter, III, Chester O.; Shelton, IV, Frederick E.; Schmid, Katherine J.; Morgan, Jerome R.; Scheib, Charles J.; Cropper, Michael S.; Aronhalt, Taylor W.; Hall, Steven G.; Timm, Richard W.; Lang, Matthew M., Retainer assembly including a tissue thickness compensator.
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  281. Baxter, III, Chester O.; Shelton, IV, Frederick E.; Schmid, Katherine J.; Morgan, Jerome R.; Scheib, Charles J.; Cropper, Michael S.; Aronhalt, Taylor W.; Hall, Steven G.; Timm, Richard W.; Lang, Matthew M., Retainer assembly including a tissue thickness compensator.
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  282. Shelton, IV, Frederick E.; Schmid, Katherine J.; Morgan, Jerome R.; Korvick, Donna L., Retainer assembly including a tissue thickness compensator.
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  283. Shelton, IV, Frederick E.; Vyakarnam, Murty, Retainer assembly including a tissue thickness compensator.
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  284. Timm, Richard W.; Shelton, IV, Frederick E., Robotic actuator assembly.
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  285. Shelton, IV, Frederick E.; Morgan, Jerome R., Robotic surgical system with removable motor housing.
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  286. Shelton, IV, Frederick E., Robotically powered surgical device with manually-actuatable reversing system.
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  287. Swensgard, Brett E.; Yates, David C.; Shelton, IV, Frederick E., Robotically-controlled motorized surgical instrument with an end effector.
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  288. Yates, David C.; Shelton, IV, Frederick E.; Huitema, Thomas W., Robotically-controlled motorized surgical instrument with an end effector.
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  289. Yates, David C.; Shelton, IV, Frederick E.; Morgan, Jerome R., Robotically-controlled motorized surgical instrument with an end effector.
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  290. Yates, David C.; Shelton, IV, Frederick E.; Morgan, Jerome R., Robotically-controlled motorized surgical instrument with an end effector.
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  291. Shelton, IV, Frederick E., Robotically-controlled shaft based rotary drive systems for surgical instruments.
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  292. Timm, Richard W.; Shelton, IV, Frederick E., Robotically-controlled shaft based rotary drive systems for surgical instruments.
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  293. Spivey, James T.; Ortiz, Mark S.; Shelton, IV, Frederick E.; Morgan, Jerome R., Robotically-controlled surgical instrument with selectively articulatable end effector.
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  294. Yates, David C.; Shelton, IV, Frederick E.; Huitema, Thomas W., Robotically-controller motorized surgical tool with an end effector.
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  295. Shelton, IV, Frederick E.; Setser, Michael E.; Weisenburgh, II, William B., Robotically-driven surgical instrument with E-beam driver.
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  296. Ortiz, Mark S.; Shelton, IV, Frederick E., Rotary actuatable surgical fastener and cutter.
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  297. Kimsey, John S.; Auld, Michael D., Rotary powered articulation joints for surgical instruments.
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  298. Auld, Michael D., Rotary powered surgical instruments with multiple degrees of freedom.
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  299. Van Sciver, Jason, Rotatable support elements for stents.
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  300. Van Sciver, Jason, Rotatable support elements for stents.
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  301. Van Sciver, Jason, Rotatable support elements for stents.
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  302. Van Sciver, Jason, Rotatable support elements for stents.
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  303. Van Sciver, Jason, Rotatable support elements for stents.
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  304. Hossainy,Syed F. A.; Mirzaee,Daryush, Selective coating of medical devices.
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  305. Tochterman, Andrew J.; Fox, William J.; Harold, Nathan, Selectively coating luminal surfaces of stents.
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  306. Tieu, Tai D.; Gulachenski, Joseph, Self-expanding prosthesis.
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  307. Goraltchouk, Alexei; Drubetsky, Lev; Cummings, Gerald F.; Herrmann, Robert A.; Naimagon, Alexander, Self-retainers with supporting structures on a suture.
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  308. Goraltchouk, Alexei; Naimagon, Alexander; Cummings, Gerald F.; Drubetsky, Lev; Herrmann, Robert A., Self-retaining suture with variable dimension filament and method.
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  309. Leung, Jeffrey C.; Ruff, Gregory L.; Megaro, Matthew A., Self-retaining sutures having effective holding strength and tensile strength.
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  310. Leung, Jeffrey C.; Ruff, Gregory L.; Megaro, Matthew A., Self-retaining sutures having effective holding strength and tensile strength.
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  311. Herrmann, Robert A.; Goraltchouk, Alexei; Drubetsky, Lev, Self-retaining sutures including tissue retainers having improved strength.
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  312. Herrmann, Robert A.; Goraltchouk, Alexei; Drubetsky, Lev, Self-retaining sutures including tissue retainers having improved strength.
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  313. Goraltchouk, Alexei; Drubetsky, Lev; Cummings, Gerald F.; Herrmann, Robert A.; Naimagon, Alexander, Self-retaining sutures with bi-directional retainers or uni-directional retainers.
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  314. Goraltchouk, Alexei; Drubetsky, Lev; Cummings, Gerald F.; Herrmann, Robert A.; Naimagon, Alexander, Self-retaining sutures with heat-contact mediated retainers.
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  315. Goraltchouk, Alexei; Drubetsky, Lev; Cummings, Gerald F.; Herrmann, Robert A.; Naimagon, Alexander, Self-retaining sutures with retainers formed from molten material.
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  316. Hunter, William L., Self-retaining systems for surgical procedures.
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  317. Leimbach, Richard L.; Overmyer, Mark D.; Swensgard, Brett E.; Adams, Shane R., Sensor arrangements for absolute positioning system for surgical instruments.
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  318. Baber, Daniel L.; Leimbach, Richard L.; Albrecht, Thomas E., Sensor straightened end effector during removal through trocar.
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  319. Morgan, Jerome R.; Shelton, IV, Frederick E., Shroud retention arrangement for sterilizable surgical instruments.
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  320. Shelton, IV, Frederick E.; Yates, David C.; Harris, Jason L., Signal and power communication system positioned on a rotatable shaft.
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  321. Baber, Daniel L.; Swayze, Jeffrey S.; Beckman, Andrew T.; Shelton, IV, Frederick E., Smart cartridge wake up operation and data retention.
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  322. Shelton, IV, Frederick E.; Harris, Jason L.; Beckman, Andrew T., Smart sensors with local signal processing.
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  323. Shelton, IV, Frederick E.; Setser, Michael E.; Weisenburgh, II, William B., Staple cartridge.
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  324. Shelton, IV, Frederick E.; Baxter, III, Chester O., Staple cartridge assembly comprising an implantable layer.
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  325. Shelton, IV, Frederick E.; Baxter, III, Chester O.; Swayze, Jeffrey S.; Harris, Jason L., Staple cartridge assembly including features for controlling the rotation of staples when being ejected therefrom.
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  326. Swayze, Jeffrey S.; Shelton, IV, Frederick E.; Vendely, Michael J.; Baxter, III, Chester O.; Harris, Jason L.; Aronhalt, Taylor W., Staple cartridge assembly without a bottom cover.
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  327. Baxter, III, Chester O.; Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Aronhalt, Taylor W.; Schmid, Katherine J., Staple cartridge comprising a compressible layer.
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  328. Shelton, IV, Frederick E.; Baxter, III, Chester O., Staple cartridge comprising a compressible portion.
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  329. Baxter, III, Chester O.; Morgan, Jerome R.; Shelton, IV, Frederick E., Staple cartridge comprising a releasable adjunct material.
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  330. Aronhalt, Taylor W.; Vendely, Michael J.; Clauda, Phillip H., Staple cartridge comprising a releasable cover.
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  331. Shelton, IV, Frederick E.; Murray, Michael A.; Hess, Christopher J.; Weisenburgh, II, William B.; Morgan, Jerome R.; Hall, Steven G., Staple cartridge comprising a staple driver arrangement.
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  332. Shelton, IV, Frederick E.; Weaner, Lauren S.; Morgan, Jerome R.; Vendely, Michael J.; Aronhalt, Taylor W.; Baxter, III, Chester O.; Zeiner, Mark S., Staple cartridge comprising a tissue thickness compensator.
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  333. Shelton, IV, Frederick E.; Baxter, III, Chester O.; Swayze, Jeffrey S.; Morgan, Jerome R.; Rhee, Sora; Aronhalt, Taylor W., Staple cartridge comprising a variable thickness compressible portion.
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  334. Shelton, IV, Frederick E.; Weaner, Lauren S.; Morgan, Jerome R.; Vendely, Michael J.; Aronhalt, Taylor W., Staple cartridge comprising an adjunct material.
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  335. Baxter, III, Chester O.; Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Aronhalt, Taylor W.; Schmid, Katherine J., Staple cartridge comprising an implantable layer.
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  336. Shelton, IV, Frederick E.; Baxter, III, Chester O.; Aronhalt, Taylor W.; Young, Joseph E., Staple cartridge comprising compressible distortion resistant components.
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  337. Baxter, III, Chester O.; Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Aronhalt, Taylor W.; Schmid, Katherine J., Staple cartridge comprising implantable layers.
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  338. Shelton, IV, Frederick E.; Baxter, III, Chester O.; Aronhalt, Taylor W.; Morgan, Jerome R.; Young, Joseph E., Staple cartridge comprising multiple regions.
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  339. Hess, Christopher J.; Morgan, Jerome R.; Shelton, IV, Frederick E.; Weisenburgh, II, William B., Staple cartridge comprising staples including a lateral base.
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  340. Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Morgan, Jerome R., Staple cartridge comprising staples with different unformed heights.
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  341. Schmid, Katherine J.; Shelton, IV, Frederick E.; Baxter, III, Chester O.; Aronhalt, Taylor W.; Young, Joseph E., Staple cartridge including collapsible deck.
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  342. Schmid, Katherine J.; Baxter, III, Chester O.; Aronhalt, Taylor W.; Young, Joseph E.; Shelton, IV, Frederick E., Staple cartridge including collapsible deck arrangement.
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  343. Hall, Steven G.; Swensgard, Brett E., Staple cartridge tissue thickness sensor system.
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  344. Shelton, IV, Frederick E., Staple cartridges for forming staples having differing formed staple heights.
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  345. Shelton, IV, Frederick E., Staple cartridges for forming staples having differing formed staple heights.
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  346. Shelton, IV, Frederick E., Staple cartridges for forming staples having differing formed staple heights.
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  347. Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Harris, Jason L., Staples configured to support an implantable adjunct.
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  348. Shelton, IV, Frederick E.; Baxter, III, Chester O.; Aronhalt, Taylor W., Stapling assemblies comprising a layer.
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  349. Moore, Kyle P.; Shelton, IV, Frederick E.; Weisenburgh, II, William B.; Morgan, Jerome R.; Ransick, Mark H.; Timperman, Eugene L., Stapling assembly.
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  350. Moore, Kyle P.; Shelton, IV, Frederick E.; Weisenburgh, II, William B.; Morgan, Jerome R.; Ransick, Mark H.; Timperman, Eugene L., Stapling assembly.
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  351. Moore, Kyle P.; Shelton, IV, Frederick E.; Weisenburgh, II, William B.; Morgan, Jerome R.; Ransick, Mark H.; Timperman, Eugene L., Stapling assembly.
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  352. Swayze, Jeffrey S.; Hueil, Joseph C.; Morgan, Jerome R.; Shelton, IV, Frederick E., Stapling assembly configured to produce different formed staple heights.
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  353. Shelton, IV, Frederick E., Stapling assembly for forming different formed staple heights.
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  354. Shelton, IV, Frederick E., Stapling assembly for forming different formed staple heights.
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  355. Shelton, IV, Frederick E.; Harris, Jason L., Stapling end effector configured to compensate for an uneven gap between a first jaw and a second jaw.
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  356. Schmid, Katherine J.; Morgan, Jerome R.; Korvick, Donna L.; Shelton, IV, Frederick E., Stapling system comprising an adjunct and a flowable adhesive.
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  357. Shelton, IV, Frederick E.; Schmid, Katherine J.; Scheib, Charles J.; Aronhalt, Taylor W.; Swayze, Jeffrey S.; Contiliano, Joseph H.; Yang, Chunlin; Henderson, Cortney E.; Aldridge, Jeffrey L., Stapling system comprising implantable layers.
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  358. Baxter, III, Chester O.; Bedi, James J., Stapling system configured to produce different formed staple heights.
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  359. Shelton, IV, Frederick E.; Baxter, III, Chester O.; Aronhalt, Taylor W.; Young, Joseph E., Stapling system including an actuation system.
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  360. Shelton, IV, Frederick E., Stapling systems.
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  361. Santini, Jr.,John T.; Hutchinson,Charles E., Stent for controlled release of drug.
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  362. Fox, Jason; Harold, Nathan; Templin, Barry; Tochterman, Andrew, Stent mandrel fixture and method for selectively coating surfaces of a stent.
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  363. Fox,Jason; Harold,Nathan; Templin,Barry; Tochterman,Andrew, Stent mandrel fixture and method for selectively coating surfaces of a stent.
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  364. Pacetti,Stephen D.; Villareal,Plaridel K., Stent mounting assembly and a method of using the same to coat a stent.
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  365. Santos, Veronica J.; Prabhu, Santosh, Stent with drug coating.
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  366. Santos, Veronica J.; Prabhu, Santosh, Stent with drug coating.
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  367. Santos, Veronica J.; Prabhu, Santosh, Stent with drug coating.
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  368. Santos,Veronica J; Prabhu,Santosh, Stent with drug coating.
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  369. Santos, Veronica J.; Prabhu, Santosh, Stent with drug coating with variable release rate.
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  370. Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D.; Swensgard, Brett E.; Lytle, IV, Thomas W.; Shelton, IV, Frederick E.; Houser, Kevin L., Sterilization verification circuit.
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  371. Leung, Jeffrey C.; Megaro, Matthew A.; Ruff, Gregory; Kaplan, Andrew, Subcutaneous sinusoidal wound closure utilizing one-way suture.
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  372. Beckman, Andrew T.; Nalagatla, Anil K.; Hibner, John A.; Shelton, IV, Frederick E., Surgical apparatus configured to assess whether a performance parameter of the surgical apparatus is within an acceptable performance band.
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  373. Beckman, Andrew T.; Nalagatla, Anil K.; Koch, Jr., Robert L.; Hibner, John A.; Shelton, IV, Frederick E., Surgical apparatus configured to track an end-of-life parameter.
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  374. Shelton, IV, Frederick E., Surgical cutting and fastening instrument.
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  375. Morgan, Jerome R.; Shelton, IV, Frederick E., Surgical cutting and fastening instrument with apparatus for determining cartridge and firing motion status.
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  376. Morgan, Jerome R.; Shelton, IV, Frederick E., Surgical cutting and fastening instrument with apparatus for determining cartridge and firing motion status.
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  377. Shelton, IV, Frederick E.; Baxter, III, Chester O.; Yates, David C., Surgical end effectors having angled tissue-contacting surfaces.
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  378. Shelton, IV, Frederick E.; Baxter, III, Chester O.; Yates, David C., Surgical end effectors having angled tissue-contacting surfaces.
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  379. Baxter, III, Chester O.; Swayze, Jeffrey S.; Dunki-Jacobs, Adam R., Surgical end effectors with dual cam actuated jaw closing features.
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  380. Huitema, Thomas W.; Scheib, Charles J.; Henderson, Cortney E.; Shelton, IV, Frederick E.; Harris, Jason L., Surgical end effectors with firing element monitoring arrangements.
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  381. Huitema, Thomas W.; Schellin, Emily A.; Hueil, Geoffrey C.; Shelton, IV, Frederick E., Surgical fastener cartridges with driver stabilizing arrangements.
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  382. Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Baxter, III, Chester O., Surgical fastening apparatus with a rotary end effector drive shaft for selective engagement with a motorized drive system.
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  383. Shelton, IV, Frederick E.; Ouwerkerk, John N.; Morgan, Jerome R., Surgical instrument.
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  384. Shelton, IV, Frederick E.; Ouwerkerk, John N.; Morgan, Jerome R., Surgical instrument.
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  385. Shelton, IV, Frederick E.; Ouwerkerk, John N.; Morgan, Jerome R.; Swayze, Jeffrey S., Surgical instrument.
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  386. Shelton, IV, Frederick E.; Morgan, Jerome R.; Harris, Jason L.; Swayze, Jeffrey S.; Baxter, III, Chester O., Surgical instrument assembly comprising a flexible articulation system.
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  387. Baxter, III, Chester O.; Dunki-Jacobs, Adam R.; Swayze, Jeffrey S.; Baber, Daniel L.; Shelton, IV, Frederick E., Surgical instrument assembly comprising a lockable articulation system.
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  388. Parihar, Shailendra K.; Hibner, John A., Surgical instrument comprising a closing drive and a firing drive operated from the same rotatable output.
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  389. Yates, David C.; Huitema, Thomas W.; Shelton, IV, Frederick E., Surgical instrument comprising a control system.
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  390. Shelton, IV, Frederick E.; Morgan, Jerome R., Surgical instrument comprising a firing system including a compliant portion.
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  391. Parihar, Shailendra K.; Kimsey, John S.; Koch, Jr., Robert L.; Nalagatla, Anil K.; Nguyen, Anthony T., Surgical instrument comprising a gap setting system.
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  392. Overmyer, Mark D.; Auld, Michael D.; Adams, Shane R.; Shelton, IV, Frederick E.; Harris, Jason L., Surgical instrument comprising a lockable battery housing.
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  393. Morgan, Jerome R.; Shelton, IV, Frederick E., Surgical instrument comprising a plurality of articulation joints.
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  394. Leimbach, Richard L.; Beckman, Andrew T.; Schultz, Darwin L.; Adams, Shane R., Surgical instrument comprising a rotatable shaft.
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  395. Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D.; Shelton, IV, Frederick E., Surgical instrument comprising a sensor system.
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  396. Shelton, IV, Frederick E.; Morgan, Jerome R., Surgical instrument comprising an adjustable system configured to accommodate different jaw heights.
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  397. Shelton, IV, Frederick E.; Swayze, Jeffrey S., Surgical instrument comprising drive systems.
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  398. Lytle, IV, Thomas W.; Overmyer, Mark D.; Adams, Shane R.; Leimbach, Richard L.; Shelton, IV, Frederick E.; Swensgard, Brett E.; Houser, Kevin L., Surgical instrument comprising interactive systems.
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  399. Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D.; Swensgard, Brett E.; Lytle, IV, Thomas W.; Shelton, IV, Frederick E.; Houser, Kevin L., Surgical instrument control circuit having a safety processor.
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  400. Shelton, IV, Frederick E.; Swayze, Jeffrey S., Surgical instrument drive systems.
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  401. Shelton, IV, Frederick E.; Morgan, Jerome R.; Doll, Kevin R.; Swayze, Jeffrey S.; Timperman, Eugene L., Surgical instrument having a feedback system.
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  402. Shelton, IV, Frederick E.; Morgan, Jerome J.; Leimbach, Richard L.; Overmyer, Mark D., Surgical instrument having force feedback capabilities.
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  403. Shelton, IV, Frederick E.; Morgan, Jerome R.; Leimbach, Richard L.; Ouwerkerk, John N., Surgical instrument having force feedback capabilities.
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  404. Hall, Steven G.; Baber, Daniel L.; Leimbach, Richard L., Surgical instrument soft stop.
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  405. Shelton, IV, Frederick E.; Giordano, James R.; Swayze, Jeffrey S., Surgical instrument system.
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  406. Shelton, IV, Frederick E.; Giordano, James R.; Swayze, Jeffrey S., Surgical instrument system.
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  407. Morgan, Jerome R.; Shelton, IV, Frederick E., Surgical instrument system comprising a firing system including a rotatable shaft and first and second actuation ramps.
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  408. Savage, Jeffrey L.; Uth, Joshua R.; Beckman, Andrew T.; Baxter, III, Chester O., Surgical instrument system comprising an inspection station.
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  409. Kerr, Wendy A.; Lytle, IV, Thomas W.; Overmyer, Mark D.; Swensgard, Brett E.; Sackett, Kevin D.; Leimbach, Richard L.; Houser, Kevin L.; Morgan, Jerome R.; Shelton, IV, Frederick E., Surgical instrument system comprising lockable systems.
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  410. Morgan, Jerome R.; Shelton, IV, Frederick E., Surgical instrument system configured to detect resistive forces experienced by a tissue cutting implement.
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  411. Yates, David C.; Shelton, IV, Frederick E.; Giordano, James R., Surgical instrument system for evaluating tissue impedance.
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  412. Lytle, IV, Thomas W.; Shelton, IV, Frederick E.; Morgan, Jerome R., Surgical instrument systems comprising an articulatable end effector and means for adjusting the firing stroke of a firing member.
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  413. Shelton, IV, Frederick E.; Baxter, III, Chester O., Surgical instrument with an anvil that is selectively movable about a discrete non-movable axis relative to a staple cartridge.
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  414. Hunter, Morgan R.; Schultz, Darwin L.; Worthington, Sarah A.; Shelton, IV, Frederick E.; Weaner, Lauren S.; Vendely, Michael J., Surgical instrument with articulating and axially translatable end effector.
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  415. Shelton, IV, Frederick E.; Ouwerkerk, John N.; Morgan, Jerome R.; Swayze, Jeffrey S., Surgical instrument with automatically-returned firing member.
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  416. Shelton, IV, Frederick E.; Ouwerkerk, John N.; Morgan, Jerome R.; Swayze, Jeffrey S., Surgical instrument with firing actuator lockout.
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  417. Shelton, IV, Frederick E.; Baxter, III, Chester O.; Harris, Jason L.; Swayze, Jeffrey S., Surgical instruments with articulatable end effectors and improved firing beam support arrangements.
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  418. Shelton, IV, Frederick E.; Morgan, Jerome R.; Harris, Jason L.; Swayze, Jeffrey S.; Baxter, III, Chester O., Surgical instruments with articulatable end effectors and movable firing beam support arrangements.
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  419. Shelton, IV, Frederick E.; Morgan, Jerome R.; Baxter, III, Chester O., Surgical instruments with improved closure arrangements.
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  420. Hunter, Morgan R.; Schultz, Darwin L.; Dunki-Jacobs, Adam R.; Baxter, III, Chester O.; Swayze, Jeffrey S., Surgical instruments with tensioning arrangements for cable driven articulation systems.
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  421. Buncke, Harry J., Surgical methods using one-way suture.
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  422. Adams, Shane R.; Yates, David C.; Shelton, IV, Frederick E.; Harris, Jason L., Surgical shaft assemblies with watertight housings.
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  423. Harris, Jason L.; Morgan, Jerome R.; Zeiner, Mark S.; Shelton, IV, Frederick E., Surgical staple and driver arrangements for staple cartridges.
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  424. Harris, Jason L.; Morgan, Jerome R.; Zeiner, Mark S.; Shelton, IV, Frederick E., Surgical staple and driver arrangements for staple cartridges.
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  425. Murray, Michael A.; Morgan, Jerome R.; Hess, Christopher J.; Weisenburgh, II, William B.; Zwolinski, Andrew M., Surgical staple cartridge.
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  426. Harris, Jason L.; Shelton, IV, Frederick E., Surgical staple cartridge staple drivers with central support features.
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  427. Harris, Jason L.; Shelton, IV, Frederick E.; Baxter, III, Chester O., Surgical staple cartridges with driver arrangements for establishing herringbone staple patterns.
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  428. Harris, Jason L.; Shelton, IV, Frederick E.; Baxter, III, Chester O., Surgical staple driver arrays.
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  429. Yates, David C.; Shelton, IV, Frederick E., Surgical stapler having current mirror-based motor control.
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  430. Yates, David C.; Shelton, IV, Frederick E., Surgical stapler having downstream current-based motor control.
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  431. Overmyer, Mark D.; Yates, David C.; Shelton, IV, Frederick E.; Adams, Shane R.; Leimbach, Richard L., Surgical stapler having motor control based on an electrical parameter related to a motor current.
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  432. Overmyer, Mark D.; Yates, David C.; Shelton, IV, Frederick E.; Adams, Shane R.; Harris, Jason L., Surgical stapler having temperature-based motor control.
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  433. Schmid, Katherine J.; Baxter, III, Chester O.; Aronhalt, Taylor W.; Young, Joseph E.; Shelton, IV, Frederick E., Surgical stapler with stationary staple drivers.
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  434. Baxter, III, Chester O.; Shelton, IV, Frederick E.; Ballard, Kenneth D., Surgical staples comprising features for improved fastening of tissue.
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  435. Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E.; Hueil, Geoffrey C.; Ortiz, Mark S.; Hoffman, Douglas B.; Weizman, Patrick A.; Bruewer, Dean B.; Blair, Gregory B., Surgical stapling apparatus.
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  436. Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E.; Hueil, Geoffrey C.; Ortiz, Mark S.; Hoffman, Douglas B.; Weizman, Patrick A.; Bruewer, Dean B.; Blair, Gregory B., Surgical stapling apparatus.
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  437. Huang, Zhifan F.; Morgan, Jerome R.; Shelton, IV, Frederick E., Surgical stapling apparatus comprising a tissue stop.
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  438. Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E.; Hueil, Geoffrey C.; Ortiz, Mark S.; Hoffman, Douglas B.; Weizman, Patrick A.; Bruewer, Dean B.; Blair, Gregory B., Surgical stapling apparatus including firing force regulation.
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  439. Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E.; Hueil, Geoffrey C.; Ortiz, Mark S.; Hoffman, Douglas B.; Weizman, Patrick A.; Bruewer, Dean B.; Blair, Gregory B., Surgical stapling apparatus including firing force regulation.
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  440. Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E., Surgical stapling apparatus with interlockable firing system.
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  441. Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E., Surgical stapling apparatuses with lockable end effector positioning systems.
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  442. Hall, Steven G.; Tanguay, Randall J.; Messerly, Jeffrey D.; Robertson, Galen C.; Zwolinski, Andrew M.; Shelton, IV, Frederick E.; Hueil, Geoffrey C.; Ortiz, Mark S.; Hoffman, Douglas B.; Weizman, Patrick A.; Bruewer, Dean B.; Blair, Gregory B., Surgical stapling assembly comprising a selector arrangement.
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  443. Shelton, IV, Frederick E.; Morgan, Jerome R., Surgical stapling device.
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  444. Shelton, IV, Frederick E.; Morgan, Jerome R., Surgical stapling device having supports for a flexible drive mechanism.
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  445. Shelton, IV, Frederick E.; Morgan, Jerome R., Surgical stapling device having supports for a flexible drive mechanism.
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  446. Shelton, IV, Frederick E.; Morgan, Jerome R.; Balek, Stephen J., Surgical stapling device with a curved end effector.
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  448. Shelton, IV, Frederick E.; Morgan, Jerome R.; Balek, Stephen J., Surgical stapling device with a curved end effector.
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  449. Shelton, IV, Frederick E.; Morgan, Jerome R.; Balek, Stephen J., Surgical stapling device with a curved end effector.
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  450. Shelton, IV, Frederick E.; Morgan, Jerome R., Surgical stapling device with a curved staple cartridge.
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  451. Shelton, IV, Frederick E.; Morgan, Jerome R., Surgical stapling devices having laterally movable anvils.
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  452. Shelton, IV, Frederick E.; Setser, Michael E.; Weisenburgh, II, William B., Surgical stapling instrument configured to apply a compressive pressure to tissue.
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  453. Shelton, IV, Frederick E.; Setser, Michael E.; Weisenburgh, II, William B., Surgical stapling instrument having a clearanced opening.
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  454. Hess, Christopher J.; Weisenburgh, II, William B.; Shelton, IV, Frederick E.; Morgan, Jerome R., Surgical stapling instrument having a releasable buttress material.
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  455. Shelton, IV, Frederick E.; Balek, Stephen J.; Timperman, Eugene L., Surgical stapling instrument having a restraining member.
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  456. Leimbach, Richard L.; Adams, Shane R.; Overmyer, Mark D.; Swensgard, Brett E.; Lytle, IV, Thomas W.; Shelton, IV, Frederick E.; Houser, Kevin L., Surgical stapling instrument system.
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  457. Huang, Zhifan F.; Boudreaux, Chad P.; Hueil, Joseph C.; Bruewer, Dean B.; Smith, David B., Surgical stapling instrument with an articulatable end effector.
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  458. Huang, Zhifan F.; Boudreaux, Chad P.; Hueil, Joseph C.; Bruewer, Dean B.; Smith, David B., Surgical stapling instrument with an articulatable end effector.
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  459. Shelton, IV, Frederick E.; Setser, Michael E.; Weisenburgh, II, William B., Surgical stapling instrument with lockout features to prevent advancement of a firing assembly unless an unfired surgical staple cartridge is operably mounted in an end effector portion of the instrument.
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  460. Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Baxter, III, Chester O., Surgical stapling instruments with rotary joint assemblies.
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  466. Shelton, IV, Frederick E.; Morgan, Jerome R., Surgical system with selectively articulatable end effector.
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  490. Anim, Jacqueline A.; Onukuri, Samardh; Silvestri, Jr., Anthony; Shelton, IV, Frederick E.; Clem, Michael F.; Vetro-Widenhouse, Tamara S., Tissue stapler having a thickness compensator comprising incorporating a hemostatic agent.
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  491. Shelton, IV, Frederick E.; Bezwada, Rao S.; Ortiz, Mark S., Tissue stapler having a thickness compensator incorporating a hydrophilic agent.
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  492. Shelton, IV, Frederick E.; Vetro-Widenhouse, Tamara S.; Yoo, Andrew C., Tissue stapler having a thickness compensator incorporating an anti-inflammatory agent.
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  493. Ming, Xintian; Huitema, Thomas W.; Rothenburger, Stephen J.; Shelton, IV, Frederick E., Tissue stapler having a thickness compensator incorporating an anti-microbial agent.
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  494. Henderson, Cortney E.; Aronhalt, Taylor W.; Yang, Chunlin; Scheib, Charles J.; Mandakolathur Vasudevan, Venkataramanan; Yoo, Andrew C.; Shelton, IV, Frederick E., Tissue stapler having a thickness compensator incorporating an oxygen generating agent.
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  495. Shelton, IV, Frederick E.; Bezwada, Rao S., Tissue stapler having a thickness compensator incorportating a hydrophobic agent.
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  496. Timm, Richard W.; Timmer, Mark D.; Widenhouse, Tamara; Lang, Matthew M.; Stammen, John L.; Knight, Gary W.; Widenhouse, Christopher W.; Weisenburgh, II, William B.; Mutchler, Stephanie A.; Ransick, Mark H.; Schmid, Katherine J.; Shelton, IV, Frederick E.; Baxter, III, Chester O., Tissue thickness compensator and method for making the same.
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  497. Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Yang, Chunlin; Henderson, Cortney E.; Aronhalt, Taylor W.; Scheib, Charles J.; Aldridge, Jeffrey L.; Schmid, Katherine J., Tissue thickness compensator comprised of a plurality of materials.
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  498. Mandakolathur Vasudevan, Venkataramanan; Aronhalt, Taylor W.; Aldridge, Jeffrey L.; Scheib, Charles J.; Yang, Chunlin; Schall, Christopher J.; Baxter, III, Chester O.; Chun, Iksoo; Bezwada, Rao S.; Conlon, Sean P.; Cropper, Michael S.; Uth, Joshua R.; Leimbach, Richard L.; Korvick, Donna L., Tissue thickness compensator comprising a plurality of capsules.
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  499. Gonzalez, Hamilton E.; Swayze, Jeffrey S.; Cropper, Michael S.; Scheib, Charles J.; Shelton, IV, Frederick E.; Johnson, Gregory W., Tissue thickness compensator comprising a plurality of layers.
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  500. Scheib, Charles J.; Shelton, IV, Frederick E., Tissue thickness compensator comprising a plurality of medicaments.
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  501. Mandakolathur Vasudevan, Venkataramanan; Henderson, Cortney E.; Aronhalt, Taylor W.; Aldridge, Jeffrey L.; Scheib, Charles J.; Yang, Chunlin; Schall, Christopher J.; Baxter, III, Chester O.; Shelton, IV, Frederick E.; Contiliano, Joseph H.; Widenhouse, Tamara; Korvick, Donna L., Tissue thickness compensator comprising a reservoir.
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  502. Shelton, IV, Frederick E.; Schmid, Katherine J.; Scheib, Charles J.; Aronhalt, Taylor W.; Lang, Matthew M.; Hall, Steven G.; Baxter, III, Chester O., Tissue thickness compensator comprising at least one medicament.
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  503. Baxter, III, Chester O.; Shelton, IV, Frederick E.; Swayze, Jeffrey S.; Aronhalt, Taylor W.; Schmid, Katherine J., Tissue thickness compensator comprising capsules defining a low pressure environment.
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  504. Schmid, Katherine J.; Morgan, Jerome R.; Korvick, Donna L.; Shelton, IV, Frederick E., Tissue thickness compensator comprising channels.
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  505. Baxter, III, Chester O.; Shelton, IV, Frederick E.; Scheib, Charles J.; Widenhouse, Christopher W.; Weisenburgh, II, William B.; Stammen, John L.; Ransick, Mark H.; Mutchler, Stephanie A.; Knight, Gary W.; Cropper, Michael S.; Conlon, Sean P.; Swayze, Jeffrey S., Tissue thickness compensator comprising controlled release and expansion.
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  506. Timmer, Mark D.; Contiliano, Joseph H.; Aronhalt, Taylor W.; Yang, Chunlin; Scheib, Charles J.; Schmid, Katherine J.; Shelton, IV, Frederick E., Tissue thickness compensator comprising fibers to produce a resilient load.
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  507. Aldridge, Jeffrey L.; Yang, Chunlin; Scheib, Charles J.; Mandakolathur Vasudevan, Venkataramanan; Aronhalt, Taylor W.; Contiliano, Joseph H.; Cropper, Michael S.; Timperman, Eugene L.; Henderson, Cortney E.; Schmid, Katherine J.; Shelton, IV, Frederick E., Tissue thickness compensator comprising resilient members.
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  508. Aldridge, Jeffrey L.; Yang, Chunlin; Scheib, Charles J.; Mandakolathur Vasudevan, Venkataramanan; Aronhalt, Taylor W.; Contiliano, Joseph H.; Cropper, Michael S.; Timperman, Eugene L.; Henderson, Cortney E.; Schmid, Katherine J.; Shelton, IV, Frederick E., Tissue thickness compensator comprising resilient members.
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  509. Swayze, Jeffrey S.; Shelton, IV, Frederick E.; Widenhouse, Tamara; Widenhouse, Christopher W.; Aronhalt, Taylor W.; Scheib, Charles J., Tissue thickness compensator comprising structure to produce a resilient load.
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  510. Shelton, IV, Frederick E.; Vyakarnam, Murty, Tissue thickness compensator comprising tissue ingrowth features.
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  511. Widenhouse, Tamara; Shelton, IV, Frederick E.; Knight, Gary W.; Baxter, III, Chester O.; Modi, Kreena R.; Schmid, Katherine J., Tissue thickness compensator configured to redistribute compressive forces.
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  514. Barton, Trevor J.; Vendely, Michael J.; Torain, Stephen M.; Hunt, John V.; Hueil, Geoffrey C.; Anim, Jacqueline A.; Attenweiler, Pamela M.; Shelton, IV, Frederick E.; Leimbach, Richard L.; Korvick, Donna L.; Uth, Joshua R.; Onukuri, Samardh, Tissue thickness compensator having improved visibility.
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  515. Baxter, III, Chester O.; Shelton, IV, Frederick E.; Schmid, Katherine J.; Aronhalt, Taylor W.; Johnson, Gregory W.; Stammen, John L.; Knight, Gary W.; Widenhouse, Christopher W.; Weisenburgh, II, William B.; Mutchler, Stephanie A.; Bedard, Timothy S., Tissue thickness compensators.
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  516. Baxter, III, Chester O.; Shelton, IV, Frederick E.; Schmid, Katherine J.; Aronhalt, Taylor W.; Johnson, Gregory W.; Stammen, John L.; Knight, Gary W.; Widenhouse, Christopher W.; Weisenburgh, II, William B.; Mutchler, Stephanie A.; Bedard, Timothy S., Tissue thickness compensators.
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  518. Alexander, III, Johnny H.; Henderson, Cortney E.; Miller, Christopher C.; Measamer, John P.; Schmid, Katherine J.; Shelton, IV, Frederick E.; Mutchler, Stephanie A.; Smith, Bret W.; Cropper, Michael S., Tissue thickness compensators for circular surgical staplers.
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