초록 ▼

A method and apparatus for treating obese or other patients with compulsive overeating disorder includes unilaterally or bilaterally stimulating one or both of the left and right branches of a patient's vagus nerve directly or indirectly with an electrical pulse signal generated by an implantable ne

A method and apparatus for treating obese or other patients with compulsive overeating disorder includes unilaterally or bilaterally stimulating one or both of the left and right branches of a patient's vagus nerve directly or indirectly with an electrical pulse signal generated by an implantable neurostimulator with at least one operatively coupled nerve electrode to apply the pulse signal to the selected nerve branch at a location below the patient's diaphragm. The implantable neurostimulator is programmable to enable physician programming of electrical and timing parameters of the pulse signal, to induce weight loss of the patient.

대표청구항 ▼

1. A method of treating obese patients by applying a therapy to reduce the patient's appetite, which comprises the step of bilaterally stimulating the left and right branches of the patient's vagus nerve with an electrical signal applied directly or indirectly to both of said branches at a location

1. A method of treating obese patients by applying a therapy to reduce the patient's appetite, which comprises the step of bilaterally stimulating the left and right branches of the patient's vagus nerve with an electrical signal applied directly or indirectly to both of said branches at a location below the patient's diaphragm, including programming electrical and timing parameters of said electrical signal, to give the patient a sensation of satiety and thereby induce weight loss of the patient. 2. The method of claim 1, including implanting at least one signal generator and electrodes operatively coupled thereto for generating and applying said electrical signal to both of said branches of the vagus nerve at said location. 3. The method of claim 1, including implanting at least one signal generator and electrodes operatively coupled thereto for generating and applying said electrical signal internally to a portion of the patient's nervous system other than the vagus nerve to indirectly stimulate both of said branches of the vagus nerve at said location. 4. The method of claim 1, wherein said stimulating electrical signal comprises a sequence of electrical pulses. 5. The method of claim 1, wherein the step of bilaterally stimulating comprises applying said electrical signal to hot of said branches of the vagus nerve at a location in a range of from about two to about three inches below the patient's diaphragm. 6. The method of claim 1, wherein the step of bilaterally stimulating includes applying said electrical signal intermittently, in alternating on and off intervals according to a predetermined duty cycle. 7. The method of claim 1, wherein the step of bilaterally stimulating includes applying said electrical signal continuously. 8. The method of claim 1, wherein the step of bilaterally stimulating comprises applying said electrical signal synchronously to both of said branches of the vagus nerve. 9. The method of claim 1, wherein the step of bilaterally stimulating comprises applying said electrical signal endoscopically from a portion of the patient's gastrointestinal tract. 10. The method of claim 1, wherein the step of bilaterally stimulating comprises applying said electrical signal non-invasively to a portion of the patient's nervous system other than the vagus nerve to indirectly stimulate both of said branches of the vagus nerve at said location.