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Transdermal drug delivery and analyte extraction 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61N-001/30
출원번호 US-0635892 (2000-08-10)
발명자 / 주소
  • Avrahami, Zohar
출원인 / 주소
  • Elecsys Ltd.
대리인 / 주소
    Abelman, Frayne & Schwab
인용정보 피인용 횟수 : 28  인용 특허 : 71

초록

A device for ablating the stratum corneum epidermidis of a subject, including a plurality of electrodes, which are applied to the subject's skin at respective points. A power source applies electrical energy between two or more of the plurality of electrodes, in order to cause ablation of the stratu

대표청구항

A device for ablating the stratum corneum epidermidis of a subject, including a plurality of electrodes, which are applied to the subject's skin at respective points. A power source applies electrical energy between two or more of the plurality of electrodes, in order to cause ablation of the stratu

이 특허에 인용된 특허 (71)

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  2. Eppstein Jonathan A. ; Samuels Mark A. ; Ignotz Keith D., Apparatus and method for calibrating measurement systems.
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  8. Assa Shlomo ; Rideout Jeffrey ; Paterson Scott, Apparatus for delivering energy within continuous outline.
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  11. Weaver James C. (Sudbury MA) Powell Kevin T. (Boston MA) Langer ; Jr. Robert S. (Newton MA), Control of transport of molecules across tissue using electroporation.
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  16. Tu Lily Chen ; Tu Hosheng, Devices for treating canker sores, tissues and methods thereof.
  17. Rothfritz Robert ; Kerr Scott ; Arche Glenn Steven ; Kellogg Scott ; Newman Gregory J. ; Samuels Mark A. ; Fowler Richard Lachlan ; Bambot Shabbir, Disposable calibration device.
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  21. Kost Joseph,ILX ; Pliquett Uwe,DEX ; Mitragotri Samir S. ; Langer Robert S. ; Weaver James C., Effect of electric field and ultrasound for transdermal drug delivery.
  22. Mir Lluis (Verrieres-le-Buisson FRX) Orlowski Stephane (Bourg-la-Reine FRX) Siros Michel (Antony FRX), Electric pulse applicator using pairs of needle electrodes for the treatment of biological tissue.
  23. Rexroth Frederick W. (Dunedin FL) Bays F. Barry (Seminole FL), Electrolyte purging electrode tip.
  24. Hofmann Gunter A. (San Diego CA), Electroporation system with voltage control feedback for clinical applications.
  25. Goble Nigel Mark,GBX ; Goble Colin Charles Owen,GBX, Electrosurgical instrument.
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  27. McNichols Larry A. (Coon Rapids MN) Badzinski John D. (Coon Rapids MN) Haak Ronald P. (Menlo Park CA), Electrotransport delivery device.
  28. Eppstein Jonathan A., Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers.
  29. Eppstein Jonathan A. (Atlanta GA) Eppstein Deborah A. (Salt Lake City UT) Kost Joseph (Omer MA ILX) Langer Robert S. (Newton MA), Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers.
  30. Ignotz Keith D. ; Samuels Mark A., Fluid jet blood sampling device and methods.
  31. Lakowicz Joseph R. (9142 Emerson\s Reach Columbia MD 21045) Maliwal Badri P. (Baltimore MD) Thompson Richard (7106 Bristol Rd. Baltimore MD 21212) Ozinskas Alvydas (Dayton MD), Fluorescent energy transfer immunoassay.
  32. Berndt Klaus W. (Baltimore) Gryczynski Ignacy (Baltimore) Lakowicz Joseph R. (Columbia MD), Fluorometry method and apparatus using a semiconductor laser diode as a light source.
  33. Weaver James C. ; Chen Tani ; Cullander Christopher ; Guy Richard,FRX ; Langer Robert S. ; Zewert Thomas E. ; Pliquett Uwe,DEX ; Vanbever Rita,BEX ; Prausnitz Mark R., Introduction of modifying agents into skin by electroporation.
  34. Flower Ronald J. (Vernon NJ), Iontophoretic drug delivery device having an improved controller.
  35. Flower Ronald J. ; Garde Kenneth E., Iontophoretic drug delivery system.
  36. Lakowicz Joseph R. (10037 Fox Den Rd. Ellicott City MD 21042) Szmacinski Henryk (8401 Glen Rd. Baltimore MD 21234) Terpetschnig Ewald (4308 Forest View Ave. Baltimore MD 21206), Long lifetime anisotropy (polarization) probes for clinical chemistry, immunoassays, affinity assays and biomedical rese.
  37. Lakowicz Joseph R. (Ellicott City MD) Akkaya Engin U. (Columbia MD), Long-wavelength fluorescent probe compounds for calcium ions and their use in ratiometrically measuring calcium ion conc.
  38. Ignotz Keith ; Krantz Brian ; Eppstein Jonathan, Method and apparatus for determining a duration of a medical condition.
  39. Eppstein Jonathan A., Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue.
  40. Lakowicz Joseph R. (9142 Emersons Reach Columbia MD 21045) Berndt Klaus W. (Baltimore MD) Nowaczyk Kazimierz (Baltimore MD) Szmacinski Henryk (Baltimore MD) Johnson Michael L. (Charlottesville VA), Method and apparatus for multi-dimensional phase fluorescence lifetime imaging.
  41. Eckhouse Shimon,ILX, Method and apparatus for therapeutic electromagnetic treatment.
  42. Rao Govind (Baltimore MD) Szmacinski Henryk (Baltimore MD) Lakowicz Joseph R. (10037 Fox Den Rd. Ellicott City MD 21042), Method and apparatus to perform trans-cutaneous analyte monitoring.
  43. Eggers Philip E. ; Thapliyal Hira V., Method for electrosurgical cutting and ablation.
  44. Lakowicz Joseph R. (10037 Fox Den Rd. Ellicott City MD 21042) Szmacinski Henryk (Baltimore MD), Method for optically measuring chemical analytes.
  45. Stephen Robert L. (Salt Lake City UT) Lugnani Franco (Trieste ITX) Rossi Cino (Rome ITX) Eruzzi Silvio (Mantova ITX), Method of treating schistosomal infestations by iontophoresis.
  46. Eggers Philip E. ; Thapliyal Hira V., Methods for electrosurgical dermatological treatment.
  47. Olsen Phillip M. ; Brunell Stephen M. ; Thapliyal Hira V. ; Eggers Philip E., Methods for electrosurgical dermatological treatment.
  48. Saitoh Yasuhiko (Atsugi JPX) Iwata Yasuo (Sagamihara JPX) Kuzuma Seiichi (Sagamihara JPX) Nakajima Yoshihide (Akashi JPX) Yokomizo Kanji (Nishinomiya JPX), Microbicides.
  49. Eppstein Jonathan A. ; Hatch Michael R. ; Yang Difei, Microporation of human skin for drug delivery and monitoring applications.
  50. Eppstein Jonathan A. ; Hatch Michael R. ; Yang Difei, Microporation of human skin for monitoring the concentration of an analyte.
  51. Sibalis Dan (Stony Brook NY), Multi-signal electrical transdermal drug application.
  52. Sibalis Dan (Stony Brook NY), Multi-signal electrical transdermal drug applicator.
  53. Eppstein Jonathan A., Multiple mechanical microporation of skin or mucosa.
  54. Liss Saul (Glen Rock NJ) Liss Bernard (Glen Rock NJ), Non-intrusive analgesic neuroaugmentive and iontophoretic delivery apparatus and management system.
  55. Liss Saul (Hawthorne NJ) Liss Bernard (Glen Rock NJ), Non-intrusive analgesic neuroaugmentive and iontophoretic delivery apparatus and management system.
  56. Berndt Klaus W. (Baltimore MD) Lakowicz Joseph R. (Columbia MD), Phase fluorometry using a modulated electroluminescent lamp as a light source.
  57. Eggers Philip E. ; Thapliyal Hira V., Planar ablation probe and method for electrosurgical cutting and ablation.
  58. Cheng Andrew M. L. ; Eggers Philip E. ; Thapliyal Hira V., Power supply and methods for fluid delivery in electrosurgery.
  59. Cheng Andrew M. L. ; Eggers Philip E. ; Thapliyal Hira V., Power supply for limiting power in electrosurgery.
  60. Tankovich Nikolai I. (San Diego CA) Tang Kenneth Y. (Alpine CA) Hunter Allen M. (San Diego CA), Skin surface peeling process using laser.
  61. Eppstein Jonathan A. ; Samuels Mark A. ; Ignotz Keith D. ; Newman Gregory J., Spectroscopic system with disposable calibration device.
  62. Swanson David K ; Thompson Russell B ; Fleischman Sidney D ; Panescu Dorin ; Whayne James G, Structures for supporting porous electrode elements.
  63. Eggers Philip E. ; Thapliyal Hira V., System and method for electrosurgical cutting and ablation.
  64. Eggers Philip E. ; Thapliyal Hira V., System and method for electrosurgical tissue contraction.
  65. Eggers Philip E. ; Thapliyal Hira V., System and method for epidermal tissue ablation.
  66. Eggers Andrew R. ; Eggers Philip E. ; Underwood Ronald A. ; Brunell Stephen M. ; Thapliyal Hira V., Systems and methods for electrosurgical incisions on external skin surfaces.
  67. Olsen Phillip M. ; Ellsberry Maria B. ; Hovda David C. ; Thapliyal Hira V. ; Eggers Philip E., Systems for tissue resection, ablation and aspiration.
  68. Gross Joseph (Moshav Mazor ILX), Transcutaneous drug delivery applicator.
  69. Avrahami Zohar,ILX, Transdermal drug delivery and analyte extraction.
  70. Lakowicz Joseph R. ; Burke Thomas G. ; Gryczynski Ignacy ; Malak Henryk, Two-photon and multi-photon measurement of analytes in animal and human tissues and fluids.
  71. Lakowicz Joseph R. (9142 Emerson\s Reach Columbia MD 21045) Szmacinski Henry K. (Baltimore MD), pH and pCO2 sensing by luminescent lifetimes and energy transfer.

이 특허를 인용한 특허 (28)

  1. Yanaki, Jamal S., Active electrode for transdermal medicament administration.
  2. Yanaki, Jamal S., Active transdermal medicament patch and circuit board for same.
  3. Epshtein, Haim; Vaynberg, Boris, Device, apparatus, and method of adipose tissue treatment.
  4. Epshtein, Haim; Vaynberg, Boris, Device, apparatus, and method of adipose tissue treatment.
  5. Flyash, Lion; Vaynberg, Boris, Disposable electromagnetic energy applicator.
  6. Henley, Julian L.; Chang, Kuo Wei; Potter, Joseph; Goldberg, Dennis I.; Derouin, James, Electrokinetic delivery system for self-administration of medicaments and methods therefor.
  7. Eckhouse, Shimon; Kutscher, Tuvia Dror, Hair removal apparatus for personal use and the method of using same.
  8. Joshi,Ashok V., Iontophoretic drug delivery systems.
  9. Bar-El, Yossi; Arbel, Giora, Magnetic patch coupling.
  10. Manstein, Dieter, Method and apparatus for dermatological treatment and tissue reshaping.
  11. Manstein, Dieter, Method and apparatus for dermatological treatment and tissue reshaping.
  12. Manstein, Dieter, Method and apparatus for dermatological treatment and tissue reshaping.
  13. Manstein, Dieter, Method and apparatus for dermatological treatment and tissue reshaping.
  14. Eckhouse, Shimon; Kutscher, Tuvia Dror; Vaynberg, Boris, Method and apparatus for personal skin treatment.
  15. Eckhouse, Shimon; Kutscher, Tuvia Dror; Vaynberg, Boris, Method and apparatus for personal skin treatment.
  16. Henley, Julian L.; Chang, Kuo Wei; Potter, Joseph; Goldberg, Dennis I.; Derouin, James, Methods and systems for electrokinetic delivery of a substance.
  17. Flyash, Lion; Vaynberg, Boris, Skin treatment apparatus for personal use and method for using same.
  18. Britva, Alexander; Dverin, Alexander; Karni, Ziv, Skin treatment using a multi-discharge applicator.
  19. Sun,Ying; Oakeson,Ralph W.; Wisniewski,Stephen J.; Wang,Jonas C. T., Tissue electroperforation for enhanced drug delivery.
  20. Levin, Galit; Sacks, Hagit; Rudaev, Sergey, Transdermal delivery system for cosmetic agents.
  21. Stern, Meir; Levin, Galit, Transdermal delivery system for dried particulate or lyophilized medications.
  22. Stern,Meir; Levin,Galit, Transdermal delivery system for dried particulate or lyophilized medications.
  23. Stern, Meir; Levin, Galit, Transdermal delivery system for dried particulate or lyophilized peptides and polypeptides.
  24. Birchall, James; Levin, Galit; Gershonowitz, Amikam, Transdermal delivery system for polynucleotides.
  25. Weber, Bryan; Wyeth, Richard, Treatment apparatus and methods for delivering energy at multiple selectable depths in tissue.
  26. Burns, Christopher J.; Cinco, Marlo, Treatment apparatus and methods for delivering high frequency energy across large tissue areas.
  27. Paithankar, Dilip Y.; Bhawalkar, Jayant D.; Hsia, James C., Treatment of skin by spatial modulation of thermal heating.
  28. Paithankar, Dilip Y.; Bhawalkar, Jayant D.; Hsia, James C., Treatment of skin by spatial modulation of thermal heating.
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