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특허 상세정보

MyON담기
내보내기 페이스북 공유 카카오톡 공유

Method and apparatus for the transdermal administration of a substance

특허상세정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판) A61M-005/00   
미국특허분류(USC) 604/191; 604/272
출원번호 US-0401452 (1999-09-22)
발명자 / 주소
출원인 / 주소
대리인 / 주소
    Venable LLP
인용정보 피인용 횟수 : 187  인용 특허 : 6
초록
▼

A transdermal delivery device includes a plurality of microneedles for injecting a substance such as a pharmaceutical agent into or below the stratum corneum of the skin. The device has housing formed from a top and bottom wall to define a chamber for containing a pharmaceutical agent. An inlet port is provided in the top wall of the housing for supplying the pharmaceutical agent to the chamber and directing the agent to the microneedles. The housing can have a Luer lock type fitting for coupling with a syringe having a Luer lock collar to inject the pha...

대표
청구항
▼

1. A delivery device for introducing a substance into or below the stratum corneum of a patient, said device comprising: a top wall having a top surface, a bottom surface, and at least one opening extending between said top and bottom surfaces; a bottom wall having an inner surface and an outer surface coupled to said top wall by at least one side wall and spaced from said top wall to define a reservoir therebetween for containing said substance, said bottom wall having a plurality of openings extending between said inner and outer surfaces, and said...

이 특허에 인용된 특허 (6)

  1. Yuzhakov Vadim Vladimirovich ; Sherman Faiz Feisal ; Owens Grover David ; Gartstein Vladimir. Apparatus and method for using an intracutaneous microneedle array. USP2001076256533.
  2. Cormier Michel J. N. ; Theeuwes Felix T.. Device and method for enchancing transdermal sampling. USP2001046219574.
  3. Gerstel Martin S. (Palo Alto CA) Place Virgil A. (Palo Alto CA). Drug delivery device. USP1976063964482.
  4. Ejlersen Henning Munk,DKX. Magazine and removable needle unit. USP1999105968021.
  5. Godshall Ned Allen ; Anderson R. Rox. Method and apparatus for disruption of the epidermis. USP1999035879326.
  6. Lee Hai Bang (Taejeon KRX) Shin Bung Chul (Taejeon KRX). Transdermal administration method of protein or peptide drug and its administration device thereof. USP1993105250023.

이 특허를 인용한 특허 피인용횟수: 187

  1. Ramdas, Radhakrishnan; Karri, Kartik; Sharma, Chidella Venkata Krishna Mohan. Active transdermal drug delivery system and the method thereof. USP2016059327105.
  2. Lee, Kilyeon; Lee, Moongu; Jeon, Yongho; Kim, Jaeseung. Apparatus and method for local anesthesia. USP20190110183140.
  3. Clark, III, Robert L; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Apparatus for reducing the appearance of cellulite. USP2014128906054.
  4. Tobinaga, Yoshikazu; Sugiyama, Susumu. Applicator for applying functional substances into human skin. USP2013018353861.
  5. Trautman, Joseph C.; Worsham, Robert Wade; Bayramov, Danir F.; Bowers, Danny Lee; Klemm, Steven Richard; Singh, Parminder. Applicators for microneedles. USP2014098821446.
  6. Clark, III, Robert L; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Cellulite treatment methods. USP2014118894678.
  7. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for administering compartmentalized frozen particles. USP2013108545857.
  8. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for administering compartmentalized frozen particles. USP2013108563012.
  9. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for administering compartmentalized frozen particles. USP2013108551506.
  10. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for administering compartmentalized frozen particles. USP2013128603494.
  11. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for biological remodeling with frozen particle compositions. USP2013128603495.
  12. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for biological remodeling with frozen particle compositions. USP2013128603496.
  13. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for biological remodeling with frozen particle compositions. USP2013108545806.
  14. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for biological remodeling with frozen particle compositions. USP2014058731842.
  15. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for biological remodeling with frozen particle compositions. USP2013128613937.
  16. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for biological remodeling with frozen particle compositions. USP2014078788212.
  17. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for delivery of frozen particle adhesives. USP2015069056047.
  18. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for delivery of frozen particle adhesives. USP2015069050251.
  19. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for delivery of frozen particle adhesives. USP2013108545856.
  20. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for delivery of frozen particle adhesives. USP2015069060931.
  21. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for surface abrasion with frozen particles. USP2013048409376.
  22. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for surface abrasion with frozen particles. USP2015079072799.
  23. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for surface abrasion with frozen particles. USP2014058721583.
  24. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for surface abrasion with frozen particles. USP2014058725420.
  25. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for surface abrasion with frozen particles. USP2013108545855.
  26. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for surface abrasion with frozen particles. USP2015069050070.
  27. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for surface abrasion with frozen particles. USP2015069060934.
  28. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for surface abrasion with frozen particles. USP2014058722068.
  29. Boyden, Edward S.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for therapeutic delivery with frozen particles. USP2015079072688.
  30. Boyden, Edward S.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for therapeutic delivery with frozen particles. USP2015069050317.
  31. Boyden, Edward S.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for therapeutic delivery with frozen particles. USP2014058731840.
  32. Boyden, Edward S.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for therapeutic delivery with frozen particles. USP2015069060926.
  33. Boyden, Edward S.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for therapeutic delivery with frozen particles. USP2014078793075.
  34. Boyden, Edward S.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for therapeutic delivery with frozen particles. USP2014058731841.
  35. Boyden, Edward S.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Compositions and methods for therapeutic delivery with frozen particles. USP2013108551505.
  36. Hoge, Stephen G.; de Fougerolles, Antonin; Ellsworth, Jeff Lynn. Compositions and methods of altering cholesterol levels. USP2015038980864.
  37. Vogelbaum, Michael A.; Gao, Shengqiang; Kolosi, William. Convection enhanced delivery device and system. USP2018059968765.
  38. Vogelbaum, Michael A.; Gao, Shengqiang; Kolosi, William. Convection enhanced delivery device and system. USP2018039907941.
  39. Burnett, Daniel Rogers; Hermanson, Christopher; Ahlman, James H.; Strul, Bruno. Cooling systems and methods for conductive coils. USP2017049610459.
  40. De Fougerolles, Antonin; Elbashir, Sayda M.. Delivery and formulation of engineered nucleic acids. USP2018049950068.
  41. de Fougerolles, Antonin; Elbashir, Sayda M.. Delivery and formulation of engineered nucleic acids. USP2017019533047.
  42. Simons, John K.; Frederickson, Franklyn L.. Device for applying a microneedle array. USP2015099119945.
  43. Clark, III, Robert L; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Device for dissection of subcutaneous tissue. USP2014128900262.
  44. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Devices and methods for performing subcutaneous surgery. USP2016129510849.
  45. Merchant, Adnan I.; Deem, Mark E.. Devices and methods for selectively lysing cells. USP2016029248317.
  46. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Dissection handpiece and method for reducing the appearance of cellulite. USP2017099757145.
  47. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Dissection handpiece and method for reducing the appearance of cellulite. USP2015119179928.
  48. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Dissection handpiece and method for reducing the appearance of cellulite. USP2016069364246.
  49. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Dissection handpiece and method for reducing the appearance of cellulite. USP2015049011473.
  50. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Dissection handpiece and method for reducing the appearance of cellulite. USP2015049005229.
  51. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Dissection handpiece with aspiration means for reducing the appearance of cellulite. USP2015059039722.
  52. Baker, Andrew; Ross, Russell F.; Hagan, Luke. Drug delivery device. USP2018019861801.
  53. Moga, Benjamin J.; Chase, Kent B.; Smith, Garrick D. S.. Drug delivery device. USP201007D619245.
  54. Bancel, Stephane; Schrum, Jason P.; Aristarkhov, Alexander. Engineered nucleic acids and methods of use thereof. USP2016109464124.
  55. Bancel, Stephane; Schrum, Jason P.; Aristarkhov, Alexander. Engineered nucleic acids and methods of use thereof. USP20180710022425.
  56. Schrum, Jason P.; Bancel, Stephane; Afeyan, Noubar B.. Engineered nucleic acids and methods of use thereof. USP2015119181319.
  57. Schrum, Jason P.; Bancel, Stephane; Afeyan, Noubar B.; Ejebe, Kenechi. Engineered nucleic acids and methods of use thereof. USP2016099447164.
  58. Schrum, Jason P.; Bancel, Stephane; Afeyan, Noubar B.; Ejebe, Kenechi. Engineered nucleic acids and methods of use thereof. USP2018049937233.
  59. Schrum, Jason P.; Sieczkiewicz, Gregory J.; Ejebe, Kenechi; Elbashir, Sayda M.. Engineered nucleic acids and methods of use thereof. USP2017079701965.
  60. Ballakur, Sowmya; Clark, III, Robert L.; Chomas, James E.; Brian, III, Ben F.; Clapper, David M.. Fluid-jet dissection system and method for reducing the appearance of cellulite. USP2016069358033.
  61. de Fougerolles, Antonin; Wood, Kristy M.; Valencia, Pedro. Formulation and delivery of PLGA microspheres. USP2016039271996.
  62. de Fougerolles, Antonin; Wood, Kristy M.; Valencia, Pedro. Formulation and delivery of PLGA microspheres. USP2016039295689.
  63. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Frozen compositions and array devices thereof. USP2014078784384.
  64. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Frozen compositions and methods for piercing a substrate. USP2014088798932.
  65. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Frozen compositions and methods for piercing a substrate. USP2013108568363.
  66. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Frozen compositions and methods for piercing a substrate. USP2015059040087.
  67. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Frozen compositions and methods for piercing a substrate. USP2014088798933.
  68. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Frozen compositions and methods for piercing a substrate. USP2014108858912.
  69. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Frozen piercing implements and methods for piercing a substrate. USP2014078784385.
  70. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Handpiece and methods for performing subcutaneous surgery. USP2016069358064.
  71. Clark, III, Robert L; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Handpiece for use in tissue dissection. USP2015079078688.
  72. Xu, Bai. High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances. USP2011108043250.
  73. Xu, Bai. High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances. USP2011118048017.
  74. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin. In vivo production of proteins. USP2015129221891.
  75. Yuzhakov,Vadim Vladimirovich; Sherman,Faiz Feisal; Owens,Grover David; Gartstein,Vladimir. Intracutaneous microneedle array apparatus. USP2008087416541.
  76. Alchas, Paul G.. Intradermal delivery device including a needle assembly. USP2017099750897.
  77. Pettis, Ronald J.; Down, James A.; Harvey, Noel G.. Intradermal delivery of substances. USP2013068465468.
  78. Pettis, Ronald J.; Down, James A.; Harvey, Noel G.. Intradermal delivery of substances. USP2015049005182.
  79. Pettis, Ronald J.; Down, James A.; Harvey, Noel G.. Intradermal delivery of substances. USP2015038986280.
  80. Pettis, Ronald J.; Down, James A.; Harvey, Noel G.. Intradermal delivery of substances. USP2015048998877.
  81. Pettis, Ronald J.; Down, James A.; Harvey, Noel J.. Intradermal delivery of substances. USP2016059339613.
  82. Mikszta,John A.; Alarcon,Jason B.; Dean,Cheryl; Waterston,Andrea. Intradermal delivery of vaccines and gene therapeutic agents via microcannula. USP2009017473247.
  83. Cantor, Adam S.; Frederickson, Franklyn L.; Johnson, Peter R.; Ringsred, Ted K.. Low-profile microneedle array applicator. USP2014068758298.
  84. Cantor, Adam S.; Frederickson, Franklyn L.; Johnson, Peter R.; Ringsred, Ted K.. Low-profile microneedle array applicator. USP2012098267889.
  85. Johnson, Peter R.; Emery, Marla R.; Wolter, James T.; Raeder-Devens, Jennifer E.; Duan, Daniel C.; David, Moses M.; Choi, Hye-Ok. Masking method for coating a microneedle array. USP2010127846488.
  86. Burnett, Daniel R.; Hermanson, Christopher; Ahlman, James H.; Strul, Bruno. Method and apparatus for electrical stimulation therapy. USP2015049005102.
  87. Burnett, Daniel Rogers; Hermanson, Christopher. Method and apparatus for magnetic induction therapy. USP2013058435166.
  88. Burnett, Daniel Rogers; Hermanson, Christopher. Method and apparatus for magnetic induction therapy. USP2013048430805.
  89. Rosenberg, Zeil B.. Method and apparatus for the transdermal administration of a substance. USP2005116960193.
  90. Rajguru, Amit; Burnett, Daniel R.. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces. USP2017049630004.
  91. Rajguru, Amit; Burnett, Daniel R.. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces. USP2016059339641.
  92. Pettis, Ronald J.; Harvey, Noel; Ginsberg, Barry. Method and device for controlling drug pharmacokinetics. USP2010057722595.
  93. Pettis, Ronald J.; Harvey, Noel; Ginsberg, Barry. Method and device for controlling drug pharmacokinetics. USP2015119192750.
  94. Wilkinson,Bradley M.; Newby,Mark. Method and device for intradermally delivering a substance. USP2006107115108.
  95. Singh, Parminder; Bairamov, Danir; Chen, Guohua; Worsham, Robert Wade. Method and device for transdermal delivery of parathyroid hormone using a microprojection array. USP2017069687641.
  96. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Method and system for comparing tissue ablation or abrasion data to data related to administration of a frozen particle composition. USP2014078788211.
  97. Pettis, Ronald J.; Harvey, Noel G.; Down, James A.. Method for altering drug pharmacokinetics based on medical delivery platform. USP2014048708994.
  98. Pettis, Ronald J; Harvey, Noel G; Down, James A. Method for altering drug pharmacokinetics based on medical delivery platform. USP2016019242052.
  99. Gartstein, Vladimir; Sherman, Faiz Feisal. Method for manufacturing microstructures having multiple microelements with through-holes. USP2009087578954.
  100. Choi, Hannah H.; Knutson, Gordon P.; David, Moses M.. Method of contact coating a microneedle array. USP2014068741377.
  101. Choi, Hye-Ok; Knutson, Gordon P.; David, Moses M.. Method of contact coating a microneedle array. USP2011118057842.
  102. Hye-Ok, Choi; Knutson, Gordon P.; David, Moses M.. Method of contact coating a microneedle array. USP2013048414959.
  103. Gartstein, Vladimir; Sherman, Faiz Feisal. Method of exfoliation of skin using closely-packed microstructures. USP2010117828827.
  104. Gartstein, Vladimir; Sherman, Faiz Feisal. Method of exfoliation of skin using closely-packed microstructures. USP2014048702726.
  105. Arias, Francisco; Sherman, Faiz Feisal; Owens, Grover David. Method of manufacturing microneedle structures using photolithography. USP2010077763203.
  106. Ghartey-Tagoe, Esi; Wendorf, Janet; Williams, Steve; Singh, Parminder; Worsham, Robert Wade; Trautman, Joseph C.; Bayramov, Danir; Bowers, Danny Lee; Klemm, Andrew Richard; Klemm, Steven Richard; Chen, Guohua. Method of vaccine delivery via microneedle arrays. USP2016119498524.
  107. Burnett, Daniel R.. Methods and devices for performing electrical stimulation to treat various conditions. USP2017099757584.
  108. Burnett, Daniel R.. Methods and devices for performing electrical stimulation to treat various conditions. USP2015049002477.
  109. Burnett, Daniel R.. Methods and devices for performing electrical stimulation to treat various conditions. USP2016079387338.
  110. Clark, III, Robert L; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Methods and handpiece for use in tissue dissection. USP2015038979881.
  111. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Methods and systems for ablation or abrasion with frozen particles and comparing tissue surface ablation or abrasion data to clinical outcome data. USP2014068762067.
  112. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Methods for dissection of subcutaneous tissue. USP2015069044259.
  113. Clark, III, Robert L; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Methods of tissue release to reduce the appearance of cellulite. USP2014128920452.
  114. Chen, Guohua; Ding, Zhongli; Ghartey-Tagoe, Esi; Shastry, Ashutosh; Worsham, Robert Wade; Singh, Parminder. Microarray for delivery of therapeutic agent, methods of use, and methods of making. USP2018059962534.
  115. Ringsred, Ted K.; Frederickson, Franklyn L.. Microneedle array applicator and retainer. USP2015119174035.
  116. Frederickson, Franklyn L.; Johnson, Michael D.. Microneedle array applicator device and method of array application. USP2017109789249.
  117. Frederickson, Franklyn L.; Johnson, Michael D.. Microneedle array applicator device and method of array application. USP2014078784363.
  118. Gonnelli, Robert R.; McAllister, Devin V.. Microneedle array patch. USP2012048162901.
  119. Allen, Mark G.; Prausnitz, Mark R.; McAllister, Devin V.; Cros, Florent Paul Marcel. Microneedle devices and methods of manufacture and use thereof. USP2014048708966.
  120. Park, Jung-Hwan; Prausnitz, Mark R.. Microneedle devices and production thereof. USP2016049302903.
  121. Prausnitz, Mark R.; Allen, Mark G.; Gujral, Inder-Jeet. Microneedle drug delivery device. USP2012098257324.
  122. Hegde, Anant V.; Rajguru, Amit; Burnett, Daniel Rogers; Hermanson, Christopher. Microneedle electrode. USP2013118588884.
  123. Govinda Raju, Ramesh; Beck, Patricia A.. Microneedles formed by electroplating and selectively releasing temperature sensitive layers. USP2011098012566.
  124. Le, Anthony; Bourne, Doug; Shastry, Ashutosh; Worsham, Robert Wade; Singh, Parminder. Microprojection applicators and methods of use. USP20190410245422.
  125. Sherman,Faiz Feisal; Gartstein,Vladimir. Microstructures and method for treating and conditioning skin which cause less irritation during exfoliation. USP2006117131987.
  126. Gartstein, Vladimir; Sherman, Faiz Feisal. Microstructures for delivering a composition cutaneously to skin. USP2012078216190.
  127. Gartstein,Vladimir; Sherman,Faiz Feisal. Microstructures for delivering a composition cutaneously to skin. USP2006097108681.
  128. Schrum, Jason P.; Siddiqi, Suhaib; Ejebe, Kenechi. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof. USP2016059334328.
  129. Schrum, Jason P.; Siddiqi, Suhaib; Ejebe, Kenechi. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof. USP2017059657295.
  130. Schrum, Jason P.; Siddiqi, Suhaib; Ejebe, Kenechi. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof. USP20180910064959.
  131. de Fougerolles, Antonin; Roy, Atanu; Schrum, Jason P.; Siddiqi, Suhaib; Hatala, Paul; Bancel, Stephane. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof. USP2016089428535.
  132. Chakraborty, Tirtha; de Fougerolles, Antonin. Modified polynucleotides encoding SIAH E3 ubiquitin protein ligase 1. USP2016029255129.
  133. Chakraborty, Tirtha; de Fougerolles, Antonin. Modified polynucleotides encoding apoptosis inducing factor 1. USP2016049301993.
  134. Chakraborty, Tirtha; de Fougerolles, Antonin. Modified polynucleotides encoding aquaporin-5. USP2015129220792.
  135. Chakraborty, Tirtha; de Fougerolles, Antonin; Weiss, Ron. Modified polynucleotides encoding aryl hydrocarbon receptor nuclear translocator. USP2015069050297.
  136. Chakraborty, Tirtha; de Fougerolles, Antonin. Modified polynucleotides encoding basic helix-loop-helix family member E41. USP2015089107886.
  137. Chakraborty, Tirtha; de Fougerolles, Antonin. Modified polynucleotides encoding citeD4. USP2015089114113.
  138. Chakraborty, Tirtha; de Fougerolles, Antonin. Modified polynucleotides encoding copper metabolism (MURR1) domain containing 1. USP2015089095552.
  139. Chakraborty, Tirtha; de Fougerolles, Antonin. Modified polynucleotides encoding granulysin. USP2015129216205.
  140. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Whoriskey, Susan; Weiss, Ron. Modified polynucleotides encoding hepatitis A virus cellular receptor 2. USP2017069675668.
  141. Chakraborty, Tirtha; de Fougerolles, Antonin. Modified polynucleotides encoding septin-4. USP2015109149506.
  142. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin. Modified polynucleotides for the production of biologics and proteins associated with human disease. USP2015048999380.
  143. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin. Modified polynucleotides for the production of biologics and proteins associated with human disease. USP2017119814760.
  144. Bancel, Stephane; Huang, Eric Yi-Chun. Modified polynucleotides for the production of cosmetic proteins and peptides. USP2018019878056.
  145. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins. USP2017029572897.
  146. Chakraborty, Tirtha; de Fougerolles, Antonin. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins. USP2016049303079.
  147. Chakraborty, Tirtha; de Fougerolles, Antonin; Weiss, Ron. Modified polynucleotides for the production of nuclear proteins. USP2016039283287.
  148. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin. Modified polynucleotides for the production of oncology-related proteins and peptides. USP2017039587003.
  149. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; Ellsworth, Jeff Lynn; Ejebe, Kenechi; Guild, Justin; John, Matthias; Hatala, Paul; Roy, Atanu; Schrum, Jason P.; Whoriskey, Susan; Wood, Kristy M.. Modified polynucleotides for the production of proteins. USP2017119827332.
  150. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin. Modified polynucleotides for the production of proteins. USP2016029254311.
  151. Chakraborty, Tirtha; de Fougerolles, Antonin. Modified polynucleotides for the production of proteins associated with blood and lymphatic disorders. USP2016019233141.
  152. Chakraborty, Tirtha; de Fougerolles, Antonin. Modified polynucleotides for the production of proteins associated with blood and lymphatic disorders. USP2015129220755.
  153. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin. Modified polynucleotides for the production of proteins associated with human disease. USP2017109782462.
  154. Bancel, Stephane; Chakraborty, Tirtha; de Fougerolles, Antonin; Elbashir, Sayda M.; John, Matthias; Roy, Atanu; Whoriskey, Susan; Wood, Kristy M.; Hatala, Paul; Schrum, Jason P.; Ejebe, Kenechi; Ellsworth, Jeff Lynn; Guild, Justin. Modified polynucleotides for the production of secreted proteins. USP2017119828416.
  155. Chakraborty, Tirtha; de Fougerolles, Antonin. Modified polynucleotides for the production of secreted proteins. USP2015119192651.
  156. Chakraborty, Tirtha; de Fougerolles, Antonin; Weiss, Ron. Modified polynucleotides for treating galactosylceramidase protein deficiency. USP2015079089604.
  157. Chakraborty, Tirtha; de Fougerolles, Antonin; Weiss, Ron. Modified polynucleotides for treating protein deficiency. USP2015069061059.
  158. Bourne, Doug; Shastry, Ashutosh; Le, Anthony; Singh, Parminder. Multiple impact microprojection applicators and methods of use. USP20190210195409.
  159. Garcon, Nathalie; Slaoui, Moncef Mohamed; Van Hoecke, Christian. Non-live trivalent influenza vaccine for one-dose intradermal delivery. USP2013108557251.
  160. Sharma, Krishnamohan. Personalized pain management treatments. USP2018019875340.
  161. Sharma, Krishnamohan. Personalized pain management treatments. USP20190110179239.
  162. Ramdas, Radhakrishnan; Bandaru, Bhaskara Rao; Sharma, Krishnamohan. Portable electronic therapy device and the method thereof. USP2017079710607.
  163. Maenosono,Shinya; Suzuki,Yasushi; Akitomo,Hiroshi; Hamamoto,Hidetoshi; Ishibashi,Masaki. Process for producing pad base for endermism, and pad base for endermism, and injection needle. USP2008037347835.
  164. Kraft, Joseph Wayne. Rapid local anesthesia injection cone. USP2012018088108.
  165. Kraft, Joseph Wayne. Rapid local anesthesia linear injection device. USP2013048409147.
  166. Inaba, Yoichi. Simple device for treating tinea unguium. USP2014088814837.
  167. Singh, Parminder; Worsham, Robert Wade; Trautman, Joseph C.; Bayamov, Danir; Bowers, Danny Lee; Klemm, Andrew Richard; Klemm, Steven Richard; Chen, Guohua. Solvent-cast microprotrusion arrays containing active ingredient. USP20190310238848.
  168. Singh, Parminder; Worsham, Robert Wade; Trautman, Joseph C.; Bayramov, Danir; Bowers, Danny Lee; Klemm, Andy; Klemm, Steven Richard; Chen, Guohua. Solvent-cast microprotrusion arrays containing active ingredient. USP2015089114238.
  169. Singh, Parminder; Worsham, Robert Wade; Trautman, Joseph C.; Bayramov, Danir; Bowers, Danny Lee; Klemm, Andy; Klemm, Steven Richard; Chen, Guohua. Solvent-cast microprotrusion arrays containing active ingredient. USP2016099452280.
  170. de Fougerolles, Antonin; Elbashir, Sayda M.. Split dose administration. USP2015119186372.
  171. Brandwein, David H.; Frederickson, Franklyn L.; Kropp, Karl M.. System and method for tool feedback sensing. USP20180710035008.
  172. Clark, III, Robert L.; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. System for tissue dissection and aspiration. USP20190310220122.
  173. Merchant, Adnan I.; Deem, Mark E.. Systems and devices for selective cell lysis and methods of using same. USP2016039272124.
  174. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Systems, devices and methods for making or administering frozen particles. USP2013088518031.
  175. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Systems, devices, and methods for making or administering frozen particles. USP2013048414356.
  176. Boyden, Edward S.; Cook, Daniel B.; Hyde, Roderick A.; Leuthardt, Eric C.; Myhrvold, Nathan P.; Sweeney, Elizabeth A.; Wood, Jr., Lowell L.. Systems, devices, and methods for making or administering frozen particles. USP2013078485861.
  177. Chakraborty, Tirtha; Bancel, Stephane; Hoge, Stephen G.; Roy, Atanu; de Fougerolles, Antonin; Afeyan, Noubar B.. Terminally modified RNA. USP2017039597380.
  178. Clark, III, Robert L; Chomas, James E.; Merchant, Adnan I.; Brian, III, Ben F.. Tissue treatment system for reducing the appearance of cellulite. USP2014128900261.
  179. Mikszta, John A.; Brittingham, John M.; Alarcon, Jason; Pettis, Ronald J.; Dekker, III, John P.. Topical delivery of vaccines. USP2010067731968.
  180. Bandura, Bhaskara Rao; Ramdas, Radhakrishnan; Sharma, Krishnamohan; Karri, Kartik. Transdermal analyte extraction and detection system and the method thereof. USP2017079700245.
  181. Cleary, Gary W.; Klemm, Steven R.. Transdermal delivery device. USP2009117611481.
  182. Ross, Russell Frederick; Baker, Andrew. Transdermal device containing microneedles. USP2014018636696.
  183. Ross, Russell F.; Hagan, Luke; Malkin, Alexander; Hatchett, Derek; Marks, Jacob; Lutzow, Thomas. Transdermal drug delivery device. USP20190110183156.
  184. Ghartey-Tagoe, Esi; Wendorf, Janet; Williams, Steve; Singh, Parminder; Worsham, Robert Wade; Trautman, Joseph C.; Bayramov, Danir; Bowers, Danny Lee; Klemm, Andy; Klemm, Steven Richard; Chen, Guohua. Vaccine delivery via microneedle arrays. USP2014128911749.
  185. Wilkinson,Bradley M.; Hwang,Charles G.. Valved intradermal delivery device and method of intradermally delivering a substance to a patient. USP2006057047070.
  186. Chase, Kent B.; Smith, Garrick D. S.. Wearable drug delivery device having spring drive and sliding actuation mechanism. USP2014038668675.
  187. Marcoux, Michael G.; Johnson, David R.; Klemm, Steven R.. Wound dressing, ingredient delivery device and IV hold-down, and method relating to same. USP2017129839560.

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