초록 ▼

This application relates to methods for treating dermatological disorders. The methods include administering a therapeutically effective amount of at least one fruit extract in an amount sufficient to neutralize free radicals; and a pharmaceutically acceptable carrier. Preferred fruit extracts inclu

This application relates to methods for treating dermatological disorders. The methods include administering a therapeutically effective amount of at least one fruit extract in an amount sufficient to neutralize free radicals; and a pharmaceutically acceptable carrier. Preferred fruit extracts include extracts from apricots, apples, peaches, pears, pineapples, papayas, pomegranates, cherries, kiwis, tangerines and oranges. The most preferred extract is extract from pomegranate.

대표청구항 ▼

This application relates to methods for treating dermatological disorders. The methods include administering a therapeutically effective amount of at least one fruit extract in an amount sufficient to neutralize free radicals; and a pharmaceutically acceptable carrier. Preferred fruit extracts inclu

This application relates to methods for treating dermatological disorders. The methods include administering a therapeutically effective amount of at least one fruit extract in an amount sufficient to neutralize free radicals; and a pharmaceutically acceptable carrier. Preferred fruit extracts include extracts from apricots, apples, peaches, pears, pineapples, papayas, pomegranates, cherries, kiwis, tangerines and oranges. The most preferred extract is extract from pomegranate. (Salmo salar) Fed L-Carnitine Exhibit Altered Intermediary Metabolism and Reduced Tissue Lipid, but No Change in Growth Rate" J. Nutr. 126, 1996, pp. 1937-1950. "Purina CNM Veterinary Product Guide, 1994". Kumar, M.V. et al., "Differential effects of retinoic acid on uncoupling protein-1 and leptin gene expression" J. Endocrinol, May 1998, pp. 1-7. Wolf, D.P., "A Regulatory Pathway of Thermogenesis in Brown Fat Through Retinoic Acid" Nutrition Reviews, vol. 53, No. 8, 1995, pp. 230-231. Alvarez, R. et al., "A Novel Regulatory Pathway of Brown Fat Thermogenesis" J. of Biol. Chem., 1995, pp. 5666-5673. Suryawan, A. et al., "Effect of Retinoic Acid on Differentiation of Cultured Pig Preadipocytes" J. Anim. Sci. 1997, pp. 112-117. Puigserver, P. et al., "In vitro and in vivo induction of brown adipocyte uncoupling protein (thermogenin) by retinoic acid" Biochem J., 1996, pp. 827-833. Facchini, F. et al., "Relation between dietary vitamin intake and resistance to insulin-mediated glucose disposal in healthy volunteers 1-3" American J Clin Nutr, 1996, pp. 946-949. Abstract--Scarpace, P.J. et al., "Thermoregulation with age: role of thermogenesis and uncoupling protein expression in brown adipose tissue" Proc Soc Exp Biol Med, Feb. 1994. Cassard-Doulcier et al., "In Vitro Interactions in between Nuclear Proteins and Uncoupling Proetin Gene Promoter Reveal Several Putative Transactivating Factors Including Ets 1, Retinoid X Receptor, Thyroid Hormone Receptor, and a CACCC Box-binding Protein" J. of Biol. Chem., 1994, pp. 24335-24342. McCance et al., "The Composition of Foods" Royal Soc. Chemistry, 1992, p. 81.