1,2,4-triazolo[4,3-a][1,3,5]triazine-3,5,7-substituted precursor, and process, and compounds therefrom
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
C07D-487/14
C06B-045/10
C06C-015/00
A61K-031/53
A01N-043/713
출원번호
US-0171114
(2002-06-14)
발명자
/ 주소
Koppes, William M.
Sitzmann, Michael E.
출원인 / 주소
The United States of America as represented by the Secretary of the Navy
대리인 / 주소
Homer, Mark
인용정보
피인용 횟수 :
1인용 특허 :
26
초록▼
The present invention includes a precursor compound pertaining to a 1,2,4-Triazolo[4,3-a][1,3,5]Triazine compound, particularly a 1,2,4-Triazolo[4,3-a][1,3,5]Triazine-3,5,7-Triamine, and novel fused ring structures such as triazolyl-tetrazinyl-aminotriazine compounds, and complexes and salts thereof
The present invention includes a precursor compound pertaining to a 1,2,4-Triazolo[4,3-a][1,3,5]Triazine compound, particularly a 1,2,4-Triazolo[4,3-a][1,3,5]Triazine-3,5,7-Triamine, and novel fused ring structures such as triazolyl-tetrazinyl-aminotriazine compounds, and complexes and salts thereof, and other such chemical structures.
대표청구항▼
1. A compound having the chemical formula: wherein R1is --NH2,and R2and R3are independently electron donating groups. 2. The compound of claim 1, wherein R2and R3independently comprise electron donating groups selected from the group consisting of lower alkylamino, diloweralkylamino, amino, ha
1. A compound having the chemical formula: wherein R1is --NH2,and R2and R3are independently electron donating groups. 2. The compound of claim 1, wherein R2and R3independently comprise electron donating groups selected from the group consisting of lower alkylamino, diloweralkylamino, amino, halo, aryl, lower alkoxy, lower aralkoxy, aryloxy, mercapto, and lower alkylthio. 3. The compound of claim 1, wherein R2and R3independently comprise electron donating groups selected from the group consisting of a hydroxyl salt, a carboxyl salt, --ORα,--CRα3,--OCORα,--NRα2,and SRα,where Rαgroup is an alkyl group or. 4. The compound of claim 1, wherein R2and R3independently comprise electron donating groups selected from the group consisting of amino, hydroxy, lower alkoxy, lower alkylamino and diloweralkylamino. 5. The compound of claim of claim 1, wherein either R2or R3comprise --NH2. 6. The compound of claim 1, wherein both R2and R3comprise --NH2. 7. The compound of claim 1, wherein either R2or R3comprise --OCH3. 8. The compound of claim 1, wherein both R2and R3comprise --OCH3. 9. 1,2,4-triazolo[4,3-a][1,3,5]triazine-3,5,7-triamine. 10. A compound comprising separate final product formed from diazotizing the compound of claim 1. 11. The compound of claim 10, wherein the separate final product comprises the chemical structure of: wherein R4is an electron donating group, and R5comprises a third fused ring having greater than five atoms comprising carbon atoms, nitrogen atoms, or a combination thereof. 12. The compound of claim 10, wherein the separate final product comprises chemical compositions for use in a field selected from the group consisting of pharmaceutical, energetic material, colorant, functional fluid, agricultural composition, ultraviolet stabilizer and ultraviolet absorber. 13. The compound of claim 12, wherein the separate final product comprises an energetic material selected from the group consisting of explosive, gas generator, and pyrotechnic. 14. The compound of claim 12, wherein the separate final product comprises an agricultural composition selected from the group consisting of herbicides, pesticides, fungicides and fertilizers. 15. The compound of claim 12, wherein the separate final product comprises a functional fluid. 16. The compound of claim 12, wherein the separate final product comprises a colorant selected from the group consisting of dyes, pigments and indicators. 17. The compound of claim 12, wherein the separate final product comprises a pharmaceutical. 18. A process for the preparation of 1,2,4-triazolo[4,3-a][1,3,5]triazine-3,5,7-substituted, acid salt, comprising the steps of:
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이 특허에 인용된 특허 (26)
Chen Paul (North Branford CT) Hutchison Alan (Madison CT), 1,2,4-triazolo [4,3-c]quinazolin-3-ones and 1,2,4-triazolo [4,3-c]quinazolin-3-thiones; a new class of GABA brain recept.
Chasin Mark ; Cavalla David,GBX ; Hofer Peter,CHX ; Gehrig Andre,CHX ; Wintergerst Peter,CHX, 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity.
Caulkett Peter W. R. (Macclesfield GB2) Jones Geraint (Macclesfield GB2) Collis Michael G. (Barham GB2) Poucher Simon M. (Handforth GB2), Heterocyclic compounds.
Lunt Edward (Norfolk GB2) Stevens Malcolm F. G. (Birmingham GB2) Stone Robert (Montrose AUX) Wooldridge Kenneth R. H. (Lincolnshire GB2) Newlands Edward S. (London GB2), Tetrazine derivatives.
Mertens Alfred (Schriesheim DEX) von der Saal Wolfgang (Weinhim DEX) Boehm Erwin (Ladenburg DEX) Strein Klaus (Hemsbach DEX), Tricyclic benzimidazole compounds, pharmaceutical compositions and methods of use.
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