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A method of detecting an occlusion within a flexible infusion tube by measuring samples indicative of pressures relative to instances in time. Difference values for the samples are created. The difference values are compared to percentages of other difference values. When appropriate, an occlusion s

A method of detecting an occlusion within a flexible infusion tube by measuring samples indicative of pressures relative to instances in time. Difference values for the samples are created. The difference values are compared to percentages of other difference values. When appropriate, an occlusion signal is generated in response to a comparison of a difference value to a percentage of another difference value.

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A method of detecting an occlusion within a flexible infusion tube by measuring samples indicative of pressures relative to instances in time. Difference values for the samples are created. The difference values are compared to percentages of other difference values. When appropriate, an occlusion s

A method of detecting an occlusion within a flexible infusion tube by measuring samples indicative of pressures relative to instances in time. Difference values for the samples are created. The difference values are compared to percentages of other difference values. When appropriate, an occlusion signal is generated in response to a comparison of a difference value to a percentage of another difference value. nd an outer polymer layer, the reinforcement layer defining a reinforced region of the shaft, the reinforcement layer terminating proximal of a distal end of the inner and outer layers to define an unreinforced region of the shaft; an inflatable balloon having a proximal end, a distal end, and an interior, the proximal and distal ends of the balloon connected to the distal portion of the shaft such that the reinforcement layer of the distal portion of the shaft extends into the interior of the balloon to thereby eliminate significant transitions in stiffness; an inflation port extending through the distal portion of the shaft to provide a fluid path between the lumen of the shaft and the interior of the balloon; and a seal connected to the distal portion of the shaft distal of the inflation port, the seal having a lumen sized to form a fluid seal with the movable guide wire disposed therein. 2. A micro catheter as in claim 1, wherein a plurality of inflation ports extend through the distal portion of the shaft. 3. A micro catheter as in claim 2, wherein the reinforcement layer comprises a braid, and the inflation ports are disposed between filaments of the braid. 4. A micro catheter as in claim 3, wherein the filaments are formed of a super elastic metal. 5. A micro catheter as in claim 4, further comprising a radiopaque marker band disposed between the inner and outer polymer layers adjacent the balloon. 6. A micro catheter as in claim 1, further comprising a radiopaque loaded polymer layer disposed over the outer layer adjacent the balloon. 7. A micro catheter as in claim 1, wherein the outer layer of the distal portion of the shaft includes a lubricious coating thereon, except at locations where the balloon is connected thereto. 8. A micro catheter as in claim 1, wherein the seal is formed by a reduced diameter portion of the distal portion of the shaft. 9. A micro catheter as in claim 1, wherein the seal is sized to form an interference fit with the guide wire. 10. A micro catheter as in claim 1, wherein the seal is formed of a non-elastomer. 11. A micro catheter as in claim 1, wherein the proximal portion of the shaft includes a relatively stiff tube and the mid portion of the shaft includes a relatively flexible tube. 12. A micro catheter as in claim 1 , wherein the proximal portion and the mid portion of the shaft include an outer sleeve. 13. A micro catheter as in claim 12, wherein the outer sleeve and the outer layer of the distal portion of the shaft comprise an integral tube. 14. A micro catheter as in claim 1, wherein the balloon is formed of an elastomeric polymer. 15. A micro catheter as in claim 14, wherein the elastomeric polymer comprises a thermoplastic polyisoprene rubber. 16. A micro catheter as in claim 15, wherein the thermoplastic polyisoprene rubber comprises hydrogenated polyisoprene. 17. A balloon catheter as in claim 1, further comprising a soft polymer segment connected to a distal end of the distal shaft portion and extending beyond the distal end of the distal shaft portion to define an atraumatic tip. 18. A single lumen balloon-tipped micro catheter as in claim 1, wherein the distal end of the balloon is connected to the unreinforced region of the shaft. 19. A single lumen balloon-tipped micro catheter as in claim 18, wherein the proximal end of the balloon is connected to the reinforced region of the shaft.