IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0507210
(2000-02-18)
|
발명자
/ 주소 |
- Kauer, John S.
- White, Joel E.
|
출원인 / 주소 |
- Trustees of Tufts College
|
대리인 / 주소 |
Creehan, R. DennisResnick, David S.
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인용정보 |
피인용 횟수 :
145 인용 특허 :
11 |
초록
▼
The invention relates to a chemical sensor, sensing system and sensing method which provides for a multi-sensor, cross-reactive, sensor array having a rapid response time, dynamic modulation of sampling parameters, and real-time feedback control of sampling and detection conditions. The device and m
The invention relates to a chemical sensor, sensing system and sensing method which provides for a multi-sensor, cross-reactive, sensor array having a rapid response time, dynamic modulation of sampling parameters, and real-time feedback control of sampling and detection conditions. The device and method provide for smart detection and discrimination of analytes in fluids through intelligent sampling, detection, and control algorithms. The invention further provides for a sensor array having discrete sensor elements dispersed on fluid-permeable, high surface area, porous, textured substrates. The innovative device and method exhibit high sensitivity, discrimination and detection capability for target analytes at ppb and sub ppm concentrations.
대표청구항
▼
The invention relates to a chemical sensor, sensing system and sensing method which provides for a multi-sensor, cross-reactive, sensor array having a rapid response time, dynamic modulation of sampling parameters, and real-time feedback control of sampling and detection conditions. The device and m
The invention relates to a chemical sensor, sensing system and sensing method which provides for a multi-sensor, cross-reactive, sensor array having a rapid response time, dynamic modulation of sampling parameters, and real-time feedback control of sampling and detection conditions. The device and method provide for smart detection and discrimination of analytes in fluids through intelligent sampling, detection, and control algorithms. The invention further provides for a sensor array having discrete sensor elements dispersed on fluid-permeable, high surface area, porous, textured substrates. The innovative device and method exhibit high sensitivity, discrimination and detection capability for target analytes at ppb and sub ppm concentrations. SEQ ID NO:43, SEQ ID NO:49, SEQ ID NO:53, SEQ ID NO:56, SEQ ID NO:59, SEQ ID NO:63, SEQ ID NO:66, SEQ ID NO:67, SEQ ID NO:68, and SEQ ID NO:79, and conservative amino acid substitutions thereof. 13. The chimeric adenovirus fiber protein of claim 12, wherein said nonnative amino acid sequence is selected from the group consisting of SEQ ID NO:3, SEQ ID NO:4, and SEQ ID NO:5. 14. An adenovirus comprising the chimeric adenovirus fiber protein of claim 1. 15. The adenovirus of claim 14, further comprising a genome comprising a passenger gene. 16. The adenovirus of claim 14, wherein the adenovirus does not bind a native receptor. 17. A nucleic acid encoding the protein of claim 1. 18. A vector comprising the nucleic acid of claim 17. 19. The vector of claim 18, wherein said vector is a viral vector. 20. The vector of claim 18, wherein said vector is an adenovirus vector. 21. The vector of claim 18, wherein said vector further comprises a passenger gene.
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