Automated apparatus for separating a biological sample from a two dimensional electrophoresis gel
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
C25B-011/00
C25B-013/00
C25B-009/00
출원번호
US-0859664
(2001-05-18)
발명자
/ 주소
Michael, Samuel
Goodman, Jack
Anderson, N. Leigh
출원인 / 주소
Large Scale Proteomics Corporation
대리인 / 주소
Robbins, John C.Davis, Garrett V.
인용정보
피인용 횟수 :
13인용 특허 :
18
초록▼
An automated high-throughput system for excising spots or samples from an electrophoresis slab gel includes a computer controlled robotic arm assembly and a sample plate handling assembly for supplying a sample plate to a loading station. The computer is connected to a scanner and imaging device to
An automated high-throughput system for excising spots or samples from an electrophoresis slab gel includes a computer controlled robotic arm assembly and a sample plate handling assembly for supplying a sample plate to a loading station. The computer is connected to a scanner and imaging device to identify selected sample locations on the slab gel and to direct the robotic arm to the selected locations for excising the gel spots. The cutting assembly includes a removable tray for supporting the slab gel during the cutting process and is coupled to the automated sample plate handling assembly. The sample plate handling assembly delivers a multiwell plate to the cutting assembly for receiving the gel spots. The removable tray cooperates with a scanner for identifying protein spots and includes a positioning device to position the tray in the scanner and the cutting assembly in selected locations to coordinate the scanned image with the cutting process.
대표청구항▼
An automated high-throughput system for excising spots or samples from an electrophoresis slab gel includes a computer controlled robotic arm assembly and a sample plate handling assembly for supplying a sample plate to a loading station. The computer is connected to a scanner and imaging device to
An automated high-throughput system for excising spots or samples from an electrophoresis slab gel includes a computer controlled robotic arm assembly and a sample plate handling assembly for supplying a sample plate to a loading station. The computer is connected to a scanner and imaging device to identify selected sample locations on the slab gel and to direct the robotic arm to the selected locations for excising the gel spots. The cutting assembly includes a removable tray for supporting the slab gel during the cutting process and is coupled to the automated sample plate handling assembly. The sample plate handling assembly delivers a multiwell plate to the cutting assembly for receiving the gel spots. The removable tray cooperates with a scanner for identifying protein spots and includes a positioning device to position the tray in the scanner and the cutting assembly in selected locations to coordinate the scanned image with the cutting process. al., "Filling Dual Damascene Interconnect Structures with AICu and Cu Using Ionized Magnetron Deposition," J. Vac. Sci. Technol., vol. B13, pp. 125-129, 1995. Y-W. Kim et al., "Ionized Sputter Deposition of AICu: Film Microstructure and Chemistry," J. Vac. Sci. Technol., vol. A12, pp. 3169-3175, 1994. J. Hopwood et al., "Mechanisms for Highly Ionized Magnetron Sputtering," J. Appl. Phys., vol. 78, pp. 758-765, 1995. P. Kidd, "A Magnetically Confined and ECR Heated Plasma Machine for Coating and Ion Surface Modification Use," J. Vac. Sci. Technol., vol. A9, pp. 466-473, 1991. W.M. Holber, et al., "Copper Deposition by Electron Cyclotron Resonance Plasma," J. Vac. Sci. Technol., vol. A11, pp. 2903-2910, 1993. S.M. Rossnagel, "Directional and Ionized Sputter Deposition for Microelectronics Applications," Proc. of 3rd ISSP (Tokyo), pp. 253-260, 1995. M. Matsuoka et al., Dense Plasma Production and Film Deposition by New High-Rate Sputtering Using an Electric Mirror, J. Vac. Sci. Technol., A 7 (4), 2652-2657, Jul./Aug. 1989. N. Jiwari et al., "Helicon wave Plasma reactor employing single-loop antenna," J. of Vac. Sci. Technol., A 12(4), pp. 1322-1327, Jul./Aug. 1994. Search report dated Feb. 27, 1997, EPC application No. 96308251.6. U.S. application No. 08/680,335, filed Jul. 10, 1996, (Atty. Dk. 1390-CIP/PVD/DV). U.S. application No. 08/461,575, filed Sep. 30, 1992, (Atty. Dk. 364.F1). U.S. application No. 08/310,617, filed Sep. 30, 1992, (Atty. Dk. 364.P1), US Pat#5589229. U.S. application No. 08/567/601, filed Jun. 2, 1995, (Atty. Dk. 364.P2), US Pat. #5803977. U.S. application No. 08/733,620, filed Oct. 17, 1996, (Attorney Docket # 1457/PVD/DV). U.S. application No. 08/730,722, filed Oct. 8, 1996, (Aty. Dk. 1207/MD/PVD/DV). U.S. application No. 08/907,382, filed Aug. 7, 1997, (Aty. Dk. 1957/PVD/DV). U.S. application No. 08/971,867, filed Nov. 19, 1997, (Aty. Dk. 1976.P1/MD/PVD/DV). U.S. application No. 08/857,921, filed May 16, 1997, (Aty. Dk. 1737/ND/PVD/DV). U.S. application No. 08/908,341, filed Aug. 7, 1997, (Aty. Dk. 1873/PVD/DV). ectrode, and a second electrode provided on the organic electroluminescence medium layer, substantially not containing a partition wall, comprising the steps of providing a partition wall on a substrate, and eliminating unnecessary layers from the substrate including the partition wall, characterized in that the step of eliminating the unnecessary layers is a step of attaching the adhesive sheets having the pressure sensitive adhesive layer on the substrate after the patterning on the unnecessary layers including the partition wall so as not to contact with the organic EL medium layer between the partition walls or the second electrode, and peeling off the adhesive sheets. 2. The method for producing an organic electroluminescence device according to claim 1, a production method, characterized in that the pressure sensitive adhesive layer provided in the adhesive sheets is an ultraviolet ray curing type. 3. The method for producing an organic electroluminescence device according to claim 2, characterized in that the adhesive sheets are peeled off after applying a curing process to the pressure sensitive adhesive layer of the adhesive sheets. 4. The method for producing an organic electroluminescence device according to claim 3, characterized in that the substrate and/or the unnecessary layers are preheated at the time of attaching the adhesive sheets on the substrate. 5. The method for producing an organic electroluminescence device according to claim 4, characterized in that the substrate and/or the unnecessary layers are heated after attaching the adhesive sheets on the substrate, and peeling off the adhesive sheets while maintaining the heated state. , said body portion having an internal passageway, forming a multi-layer parison, said parison comprising at least a first polymeric layer, a second polymeric layer and said barrier layer wherein said barrier layer is between said first and second layers, expanding said parison to form a tube, having an axis, a width and a wall, said first and second polymeric layers, and said barrier layer extending axially of said tube, said wall defining an internal aperture extending axially along said tube and cutting said tube generally transversely to said axis to form a flange member wherein said flange member has first and second ends and the distance between said first and second ends is less than the width of said tube and attaching one end of said flange member to said body portion with said internal aperture in registry with said internal passageway. 2. The process of claim 1 wherein said parison is expanded by applying a vacuum pressure to the external surface of said parison. 3. A process for making a fuel system component having a body portion and a flange member having a barrier for inhibiting hydrocarbon vapour flow-through comprising, forming said body portion, said body portion having an internal passageway, forming a parison, said parison comprising a barrier for inhibiting hydrocarbon vapour flow-through, expanding said parison to form a tube having an axis, a width and a wall, said wall defining an internal aperture extending axially along said tube, and cutting said tube transversely to said axis to form a flange member, wherein said flange member has first and second ends and the distance between said first and second ends is less than the width of said tube and, attaching one end of said flange member to said body portion with said internal aperture in registry with said internal passageway.
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