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A method and device for collection of a stool specimen. Formation of the device occurs in situ by providing a liquid absorbent polymer to water contained in a toilet bowl. The hydrated polymer forms a matrix that is capable of supported a stool specimen deposited thereon. The method and device provi

A method and device for collection of a stool specimen. Formation of the device occurs in situ by providing a liquid absorbent polymer to water contained in a toilet bowl. The hydrated polymer forms a matrix that is capable of supported a stool specimen deposited thereon. The method and device provides a simple, economical, and less distasteful means for collecting, sampling and evaluating a stool specimen for diagnosis and/or therapy.

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A method and device for collection of a stool specimen. Formation of the device occurs in situ by providing a liquid absorbent polymer to water contained in a toilet bowl. The hydrated polymer forms a matrix that is capable of supported a stool specimen deposited thereon. The method and device provi

A method and device for collection of a stool specimen. Formation of the device occurs in situ by providing a liquid absorbent polymer to water contained in a toilet bowl. The hydrated polymer forms a matrix that is capable of supported a stool specimen deposited thereon. The method and device provides a simple, economical, and less distasteful means for collecting, sampling and evaluating a stool specimen for diagnosis and/or therapy. sing integrating said mutagenized fusion polynucleotide into the genome of said host cell. 8. A population of test cells, comprising: a) a plurality of host cells, each host cell comprising a test nucleic acid construct which comprises (i) a regulatable promoter polynucleotide; and (ii) a fusion polynucleotide comprising a mutagenized test polynucleotide encoding a mutagenized test protein fused to a reporter gene encoding a detectable label, wherein said fusion polynucleotide is operably associated with said promoter polynucleotide, wherein expression of said fusion polynucleotide in said host cell results in expression of said detectable label; wherein said plurality of host cells comprises a plurality of different mutagenized test polynucleotides. 9. The population of claim 8, wherein said detectable label comprises GFP or a GFP variant. 10. The population of claim 8, wherein said host cell is selected from the group consisting of mammalian cells and yeast. 11. A method for identifying a mutation-sensitive region of a test protein, said method comprising: a) providing a test nucleic acid construct comprising (i) a regulatable promoter polynucleotide; and (ii) a fusion polynucleotide comprising a test polynucleotide encoding said test protein fused to a reporter gene encoding a detectable label, wherein said fusion polynucleotide is operably associated with said promoter polynucleotide, b) introducing said test nucleic acid into a plurality of different host cells; c) inducing expression of said fusion polynucleotide; d) selecting host cells wherein expression of said fusion polynucleotide results in a specific phenotype dependent upon said test protein and distinct from said detectable label, and the presence of said detectable label; e) mutagenizing said test nucleic said construct to provide a plurality of mutagenized constructs comprising a plurality of different mutagenized fusion polynucleotides; f) transforming a selected host cell with said mutagenized constructs to provide a plurality of transformed host cells; g) inducing expression of said mutagenized constructs; h) selecting a plurality of transformed host cells that exhibit said detectable label, but which do not exhibit said specific phenotype; and i) determining which polynucleotide(s) were altered in a plurality of mutagenized constructs. 12. The method of claim 11, wherein step e) further comprises recovering said test nucleic acid construct from said host cell prior to mutagenizing said test nucleic acid construct. 13. The method of claim 11, wherein said reporter gene encodes a fluorescent protein. 14. The method of claim 11, wherein said reporter gene comprises URA3. 15. The method of claim 11, wherein said mutagenized construct further comprises a selectable label. 16. The method of claim 11, wherein said plurality of different host cells comprises a plurality of different yeast strains. 17. The method of claim 11, wherein said plurality of different host cells comprises a plurality of different mammalian cell types. 18. The method of claim 11, wherein said plurality of different host cells comprises a plurality of yeast strains obtained by mutagenesis. 19. The method of claim 11, wherein said plurality of different host cells comprises a plurality of cell lines derived from different tissue types. 20. The method of claim 19, wherein said host cells are human cells.