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Compositions and methods for enhancing drug delivery across and into epithelial tissues 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/02
  • A61K-038/03
  • A61K-038/08
  • A61K-038/13
  • A61K-047/42
출원번호 US-0792480 (2001-02-23)
발명자 / 주소
  • Rothbard, Jonathan B.
  • Wender, Paul A.
  • McGrane, P. Leo
  • Sista, Lalitha V. S.
  • Kirschberg, Thorsten A.
출원인 / 주소
  • CellGate, Inc.
대리인 / 주소
    Townsend and Townsend and Crew LLP
인용정보 피인용 횟수 : 66  인용 특허 : 23

초록 ▼

This invention provides compositions and methods for enhancing delivery of drugs and other agents across epithelial tissues, including the skin, gastrointestinal tract, pulmonary epithelium, ocular tissues and the like. The compositions and methods are also useful for delivery across endothelial tis

대표청구항 ▼

This invention provides compositions and methods for enhancing delivery of drugs and other agents across epithelial tissues, including the skin, gastrointestinal tract, pulmonary epithelium, ocular tissues and the like. The compositions and methods are also useful for delivery across endothelial tis

이 특허에 인용된 특허 (23)

  1. Nichols Alfred C. (Texas City TX) Yielding K. Lemone (Galveston TX), 4-hydroxyquinaldic acid derivatives.
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  9. Katz Robert ; Tomoaia-Cotisel Maria, Method for delivering active agents to mammalian brains in a complex with eicosapentaenoic acid or docosahexaenoic acid-.
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  10. Bretton Randolph H., Method for destroying residual lens epithelial cells.
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  11. Ryser Hugues J. (Concord MA) Shen Wei-Chiang (Needham MA), Method of effecting cellular uptake of molecules.
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  12. Ryser Hugues J. P. (Concord MA) Shen Wei-Chiang (Needham MA), Method of effecting cellular uptake of molecules.
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  13. Sumner-Smith Martin (Bolton CAX) Barnett Richard W. (Mississauga CAX) Reid Lorne S. (Toronto CAX) Sonenberg Nahum (St. Luc CAX), Peptide-based inhibitors of HIV replication.
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  14. Sumner-Smith Martin,CAX ; Barnett Richard W.,CAX ; Reid Lorne S.,CAX ; Sonenberg Nahum,CAX, Peptide-based inhibitors of HIV replication.
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  15. Kabanov Alexander Victorovich ; Alakhov Valery Yulievich,CAX, Polymer linked biological agents.
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  16. Mongelli Nicola (Milan ITX) Angelucci Francesco (Milan ITX) Pesenti Enrico (Cologno Monzese ITX) Suarato Antonino (Milan ITX) Biasoli Giovanni (Gavirate ITX), Polymer-bound paclitaxel derivatives.
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  17. Brewer Stephen J. (High Wycombe GB2) Sassenfeld Helmut M. (Benson GB2), Process for the preparation of polypeptides utilizing a charged amino acid polymer and exopeptidase.
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  18. Beug Hartmut (Vienna ATX) Birnstiel Max L. (Vienna ATX) Cotten Matthew (Vienna ATX) Wagner Ernst (Langenzersdorf ATX), Protein-polycation conjugates.
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  19. Dean Richard T. (Downingtown PA) Boutin Raymond H. (Wilmington DE) Lister-James John (Glenmoore PA), Proteins modified with positively charged carriers and compositions prepared therefrom.
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  20. Frankel Alan ; Pabo Carl ; Barsoum James G. ; Fawell Stephen E. ; Pepinsky R. Blake, Tat-derived transport polypeptides and fusion proteins.
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  21. Twist ; deceased Michael (late of Toronto CAX by Harvey L. Hamburg ; Administrator ) Sumner-Smith Martin (Bolton CAX), Treatment of cytomegalovirus infection.
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  22. Twist Michael,CAX ; Barnett Richard W.,CAX ; Reid Lorne S.,CAX ; Sumner-Smith Martin,CAX, Treatment of herpesvirus infection.
    상세보기
  23. Li Chun ; Wallace Sidney ; Yu Dong-Fang ; Yang David J., Water soluble paclitaxel prodrugs.
    상세보기

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  21. Rothbard, Jonathan B.; Wender, Paul A.; McGrane, P. Leo; Sista, Lalitha V. S.; Kirschberg, Thorsten A., Compositions and methods for enhancing drug delivery across and into epithelial tissues.
    상세보기
  22. Rothbard, Jonathan B.; Wender, Paul A.; McGrane, Leo P.; Sista, Lalitha V. S.; Kirschberg, Thorsten A., Compositions and methods for enhancing drug delivery across and into ocular tissues.
    상세보기
  23. Rothbard, Jonathan B.; Wender, Paul A.; McGrane, P. Leo; Sista, Lalitha V. S.; Kirschberg, Thorsten A., Compositions and methods for enhancing drug delivery across and into ocular tissues.
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  24. Rothbard,Jonathan B.; Wender,Paul A.; McGrane,P. Leo; Sista,Lalitha V. S.; Kirschberg,Thorsten A., Compositions and methods for enhancing drug delivery across and into ocular tissues.
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