IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0519735
(2000-03-04)
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발명자
/ 주소 |
- Deem, Mark E.
- Gifford, III, Hanson S.
- French, Ronald
- Sutton, Douglas
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출원인 / 주소 |
|
대리인 / 주소 |
Heller Ehrman White & McAuliffe
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인용정보 |
피인용 횟수 :
200 인용 특허 :
101 |
초록
▼
Systems, methods and devices for performing pulmonary procedures, and in particular treating lung disease. A flow control element includes a valve that prevents airflow in the inhalation direction but permits airflow in the exhalation direction. The flow control element is guided to and positioned a
Systems, methods and devices for performing pulmonary procedures, and in particular treating lung disease. A flow control element includes a valve that prevents airflow in the inhalation direction but permits airflow in the exhalation direction. The flow control element is guided to and positioned at the site by a bronchoscope that is introduced into the patient's trachea and used to view the lungs during delivery of the flow control element. The valve may include one, two or more valve elements, and it may be collapsible for easier delivery. A source of vacuum or suction may be used to increase the amount of fluid withdrawn from the lung tissue. A device for measuring hollow structures, such as bronchioles, and a device for removing a previously-placed flow control element are disclosed as well.
대표청구항
▼
Systems, methods and devices for performing pulmonary procedures, and in particular treating lung disease. A flow control element includes a valve that prevents airflow in the inhalation direction but permits airflow in the exhalation direction. The flow control element is guided to and positioned a
Systems, methods and devices for performing pulmonary procedures, and in particular treating lung disease. A flow control element includes a valve that prevents airflow in the inhalation direction but permits airflow in the exhalation direction. The flow control element is guided to and positioned at the site by a bronchoscope that is introduced into the patient's trachea and used to view the lungs during delivery of the flow control element. The valve may include one, two or more valve elements, and it may be collapsible for easier delivery. A source of vacuum or suction may be used to increase the amount of fluid withdrawn from the lung tissue. A device for measuring hollow structures, such as bronchioles, and a device for removing a previously-placed flow control element are disclosed as well. ein the connecting link guide (26) has means (27) for defining a pressure point, which have to be overcome at the start of each following partial actuation. 6. Discharge apparatus according to claim 1, wherein two, successive partial actuations (b) bringing about an equal discharge can be performed. 7. Discharge apparatus according to claim 1, wherein at least the reversing actuations are automatically performed between two following partial actuations (b). 8. Discharge apparatus according to claim 7, wherein tension reservoirs (29) are provided and are pretensioned during the performance of a partial actuation and serve to subsequently automatically perform the reversing actuation. 9. Discharge apparatus according to claim 1, wherein the reversing actuation between the first partial actuation (a) and the first, following partial actuation (b) takes place by rotating the means for actuating relative to the casing (12), an angle of said rotation being predetermined by stop edges (31) of the connecting link guide (26). 10. Discharge apparatus according to claim 9 in which by means of a tooth system (25a, 25b) a rotation of a sleeve (34) relative to the casing (17) is blocked. 11. Discharge apparatus according to claim 1, wherein the discharge is an atomized discharge. 12. Discharge apparatus according to claim 1, wherein the media contains at least one pharmaceutical substance. 13. Discharge apparatus for media, in which the media to be discharged is stored in a container, which has first and second chambers separated from one another and into which is introduced respective media components, when mixed together the media components providing the media to be discharged, the container being placed in a casing having a discharge opening for discharging the media, means for actuating the apparatus, said means for actuating being movable relative to the casing, and in which through actuation of the means for actuating firstly a connection between the chambers of the container is produced, wherein an actuating path (c) of the means for actuating (19) is subdivided into a first partial actuating path (a) and at least two of further partial actuating paths (b) and during the first partial actuating path (a) the media components (40, 41) are mixed to form the media to be discharged and in which with each following partial actuation of the actuating means (19) is associated the discharge of a clearly defined partial charge of the media, and wherein the container (12) is placed in stable manner in a sleeve (34), which is movable relative to the casing (17) and can be brought from a starting position (35) into a discharge position and in said discharge position a fluid connection is formed between a first chamber (13a) of the container and the discharge opening (18). 14. Discharge apparatus according to claim 13, wherein the bringing of the sleeve (34) from the starting position (35) into the discharge position takes place during the first partial actuation (a) and for producing the fluidic connection between the discharge opening (18) and the first chamber (13a) of the container (12) a casing-side needle having a discharge channel (21) perforates a container-side plug. 15. Discharge apparatus according to claim 13, wherein the connection link guide (26) is constructed between the sleeve (34) and means for actuating (19) at least one sliding block (30) is constructed on the connecting means (19) and the at least one link path (32, 33) of the connecting link guide (26) on the sleeve (34). 16. Discharge apparatus according to claim 13, wherein the container (12) has a first chamber (13a) facing the discharge opening (18) of the discharge apparatus (11) and at least one further chamber (13b), and which are provided with a plug (14) axially displaceable in the container, for separating and closing the chambers, as well as a plug (14) closing the last of the chambers (13b) and on which acts the means for actuating (19). 17. Discharge apparatus for media, which has first and second chambers separated from one another and into which are introduced first and second media components respectively, when mixed together the media components providing a mixed media to be discharged, the container being placed in a casing having a discharge opening for discharging the media, means for sealing being provided for tightly sealing the container at a side facing the discharge opening, means for opening being provided and being located between the means for sealing and the discharge opening for opening the means for sealing and for connecting the second chamber with the discharge opening, means for actuating the apparatus being moveable relative to the casing and in which through actuation of the means for actuating firstly a connection between the first and second chambers of the container is opened to transfer said first media component from the first chamber to the second chamber and to mix the first and the second media component wherein an actuation path (c) of the means for actuating (19) is subdivided into a first partial actuating path (a) being a mixing path and at least two further partial actuating paths (b) being a mixing path and at least two further partial actuating paths (b) being partial discharge paths during the first actuating path (a) the media components (40, 41) are mixed to form the mixed media to be discharged and the means for sealing being opened by the means for opening due to the actuation of the means for actuating, while during each following partial actuation of the means for actuating (19) a clearly defined partial charge of the mixed media is discharged, and wherein the first chamber (13a) facing the discharge opening (18) has a volume with a gas bubble (39) and during the first partial actuation (a) by the compression of the gas bubble (19) a frictional connection can be formed between the actuating means (19) and container (12), wherein the container (12) can be brought from a starting position (35), and wherein the container (12) is preferably hermetically sealed, into a discharge position, in which a fluidic connection is produced between the discharge opening (18) and the first chamber (13a). 18. Discharge apparatus according to claim 17, wherein into the first chamber (13a) is preferably introduced a dry component. 19. Discharge apparatus according to claim 18, wherein the component is a soluble media component. 20. Discharge apparatus according to claim 19, wherein the component is a lyophilizate (40). 21. Discharge apparatus according to claim 18, wherein into the second chamber (13b) is introduced a carrier medium (41) as a media component. 22. Discharge apparatus according to claim 21, wherein the carrier media is a liquid solvent. 23. Discharge apparatus for media, which has first and second chambers separated from one another and into which are introduced first and second media components respectively, when mixed together the media components providing a mixed media to be discharged, the container being placed in a casing having a discharge opening for discharging the media, means for sealing being provided for tightly sealing the container at a side facing the discharge opening, means for opening being provided and being located between the means for sealing and the discharge opening for opening the means for sealing and for connecting the second chamber with the discharge opening, a means for actuating the apparatus being moveable relative to the casing and in which through actuation of the means for actuating firstly a connection between the first and second chambers of the container is opened to transfer said first media component from the first chamber to the second chamber and to mix the first and the second media component wherein an actuation path (c) of the means for actuating (19) is subdivided into a first partial actuating path (a) being a mixing path and at least two further partial actuating paths (b) being a mixing path and at least two further partial actuating paths (b) being partial discharge paths during the first actuating path (a) the media components (40, 41) are mixed to form the mixed media to be discharged and the means for sealing being opened by the means for opening due to the actuation of the means for actuating, while during each following partial actuation of the means for actuating (19) a clearly defined partial charge of the mixed media is discharged, and wherein during the first partial actuating path a bubble of compressed air is in the second chamber due to the transfer of a first one of the media components to the second chamber, which gas is vented through the discharge opening upon opening of the means for sealing without discharging said mixed media. 24. Discharge apparatus according to claim 23, wherein the means for opening is a hollow needle provided to pierce the means for sealing.
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