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Liquid polymeric compositions for controlled release of bioactive substances 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/00
출원번호 US-0271098 (1999-03-18)
발명자 / 주소
  • Chern, Rey T.
  • Zingerman, Joel R.
출원인 / 주소
  • Merck & Co., Inc.
대리인 / 주소
    Desai, Mitul I.
인용정보 피인용 횟수 : 9  인용 특허 : 108

초록

Controlled release of hydrophobic bioactive substances in vivo over an extended time period and without “bursts” of drug release is achieved using a liquid polymeric composition including a polymer such as poly(lactide-co-glycolide) copolymer in a mixture of hydrophilic and lipophilic solvents.

대표청구항

1. A liquid polymeric composition for controlled release of eprinomectin consisting essentially of: (a) 1 to 10% of eprinomectin; (b) 1 to 10% of a poly(lactide-co-glycolide) copolymer; wherein the weight ratio of the poly(lactide-co-glycolide) copolymer to the eprinomectin is 1:1 or less and t

이 특허에 인용된 특허 (108)

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