초록 ▼

Apparatus and methods for delivery of a drug or compound into a fluid flowing within a tube or catheter. In one embodiment a catheter includes an inner surface coated with a polymer matrix such as a hydrogel. The hydrogel includes captured within it a therapeutic agent. The method of capture may be

Apparatus and methods for delivery of a drug or compound into a fluid flowing within a tube or catheter. In one embodiment a catheter includes an inner surface coated with a polymer matrix such as a hydrogel. The hydrogel includes captured within it a therapeutic agent. The method of capture may be by various means, including photolabile bonds between the therapeutic agent and the hydrogel. The therapeutic agent is released from the hydrogel by the application of energy to the hydrogel, such as by a laser emitting a wavelength which resonates and breaks the photolabile bond. The released therapeutic agent diffuses out of the hydrogel into the liquid flowing within a lumen of the catheter.

대표청구항 ▼

Apparatus and methods for delivery of a drug or compound into a fluid flowing within a tube or catheter. In one embodiment a catheter includes an inner surface coated with a polymer matrix such as a hydrogel. The hydrogel includes captured within it a therapeutic agent. The method of capture may be

Apparatus and methods for delivery of a drug or compound into a fluid flowing within a tube or catheter. In one embodiment a catheter includes an inner surface coated with a polymer matrix such as a hydrogel. The hydrogel includes captured within it a therapeutic agent. The method of capture may be by various means, including photolabile bonds between the therapeutic agent and the hydrogel. The therapeutic agent is released from the hydrogel by the application of energy to the hydrogel, such as by a laser emitting a wavelength which resonates and breaks the photolabile bond. The released therapeutic agent diffuses out of the hydrogel into the liquid flowing within a lumen of the catheter. omprising: a microcontroller operable to engage said primary station in an access phase involving a request from a first secondary station for access to a random access channel, wherein, irrespective of a potential collision involving the first secondary station regarding a transmission of data on the random access channel said microcontroller is further operable to engage said primary station in at least two contention resolution phases subsequent to a completion of the access phase, each contention resolution phase involving the request from said first secondary station to said primary station for access to the random access channel; and a transceiver in electrical communication with said microcontroller to facilitate communications among said primary station and the first secondary station during the access phase and the at least two contention resolution phases. 8. The primary station of claim 7, wherein said microcontroller unconditionally engages said primary station in an initial contention resolution phase; and wherein said microcontroller conditionally engages said primary station in any contention resolution phase subsequent to the initial contention resolution phase. 9. A secondary station, comprising: a microcontroller operable to engage said secondary station in an access phase involving a request from said secondary station to a primary station for access to a random access channel, wherein, irrespective of a potential collision involving said secondary station regarding a transmission of data on the random access channel, said microcontroller is further operable to engage said secondary station in at least two contention resolution phases subsequent to a completion of the access phase, each contention resolution phase involving the request from said first secondary station to said primary station for access to the random access channel; and a transceiver in electrical communication with said microcontroller to facilitate communications among said secondary station and the primary station during the access phase and the at least two contention resolution phases. 10. The secondary station of claim 9, wherein said microcontroller is further operable to select an access signature from a first set of signatures and to transmit an access preamble encoded with the access signature to said primary station during the access phase; and wherein said microcontroller is further operable to select a conditional resolution signature from a second set of signatures and to transmit a conditional resolution preamble encoded with the conditional resolution signature to said primary station during a first contention resolution phase. 11. The secondary station of claim 9, wherein said microcontroller is further operable to select an access signature from a first set of signatures and to transmit an access preamble encoded with the access signature to said primary station during the access phase; and wherein said microcontroller is further operable to select a conditional resolution signature from the first set of signatures and to transmit a conditional resolution preamble encoded with the conditional resolution signature to said primary station during a first contention resolution phase. 12. The secondary station of claim 9, wherein said microcontroller is further operable to select a first conditional resolution signature from a first set of signatures and to transmit a first conditional resolution preamble encoded with the first conditional resolution signature to said primary station during a first contention r