초록 ▼

A tropical composition is provided. The topical composition can be prepared by diluting a topical composition precursor with water and adding additional components, if desired. The topical composition precursor can be prepared by melt processing a hydrophobic polymer composition that includes repeat

A tropical composition is provided. The topical composition can be prepared by diluting a topical composition precursor with water and adding additional components, if desired. The topical composition precursor can be prepared by melt processing a hydrophobic polymer composition that includes repeating pyrrolidone/alkylene groups wherein the alkylene groups contain at least 10 carbon atoms, and a hydrophilic polymer composition including repeating carboxylic groups and/or repeating hydroxyl groups. A topical composition precursor and methods for manufacturing and using a topical composition are provided by the invention.

대표청구항 ▼

1. A method for manufacturing a topical composition, the method comprising steps of:(a) melt processing a mixture to provide a topical composition precursor, the mixture comprising:(i) hydrophobic polymer composition comprising repeating pyrrolidone/alkylene groups, wherein the alkylene groups conta

1. A method for manufacturing a topical composition, the method comprising steps of:(a) melt processing a mixture to provide a topical composition precursor, the mixture comprising:(i) hydrophobic polymer composition comprising repeating pyrrolidone/alkylene groups, wherein the alkylene groups contain at least 10 carbon atoms;(ii) hydrophilic polymer composition comprising repeating carboxylic acid groups and/or repeating hydroxyl groups; and(iii) less than about 1 wt. % water; and(b) diluting the topical composition precursor to provide a water concentration of at least about 30 wt. % based on the weight of the topical composition. 2. A method according to claim 1, further comprising a step of:(a) adding at least one active ingredient to the topical composition, the active ingredient comprising at least one of antimicrobial agent, antifungal agent, anti-inflammatory agent, anti-viral agent, drugs, sunscreens, vitamins, α-hydroxy acids, surfactants, fragrances, pigments, and dyes. 3. A method according to claim 1, wherein the step of melt processing comprises mixing the hydrophobic polymer composition and the hydrophilic polymer composition at a temperature of greater than 50° C. 4. A method according to claim 1, wherein the step of melt processing comprises mixing the hydrophobic polymer composition and the hydrophilic polymer composition at a temperature of greater than 125° C. 5. A method according to claim 1, further comprising a step of:(a) diluting the topical composition precursor with water to provide a composition containing between about 30 wt. % and about 45 wt. % water based on the weight of the topical composition. 6. A method according to claim 5, further comprising a step of:(a) further diluting the topical composition in a separate step to provide a composition containing at least about 95 wt. % water based on the weight of the topical composition. 7. A method according to claim 1, further comprising a step of:(a) adding surfactant to the topical composition. 8. A method according to claim 7, wherein the surfactant comprises at least one of an ethoxylated surfactant, a propoxylated surfactant, an ethoxylated-propoxylated surfactant, and a mixture thereof. 9. A method according to claim 1, wherein the composition comprises between about 30 wt. % and about 45 wt. % water. 10. A method according to claim 1, wherein the composition comprises between about 3 wt. % and about 10 wt. % of the hydrophilic polymer composition and between about 30 wt. % and about 50 wt. % of the hydrophobic polymer composition. 11. A method according to claim 1, wherein the topical composition comprises between about 70 wt % and about 96 wt. % water. 12. A method according to claim 1, wherein the hydrophobic polymer composition comprises a mixture of at least two different poly(vinylpyrrolidone/alkylene) polymers, wherein the alkylene group of each polymer contains at least about 10 carbon atoms. 13. A method according to claim 1, wherein the hydrophilic polymer composition comprises at least one of:(a) polyacrylic acid having a weight average molecular weight of at least about 50,000 and exhibiting less than 1% cross-linking;(b) poly(maleic acidlmethylvinylether) copolymer having a weight average molecular weight of at least about 50,000;(c) starch;(d) derivatives of starch;(e) cellulose;(f) derivatives of cellulose;(g) carboxymethyl cellulose;(h) polyvinyl alcohol;(i) cyclodextrins;(j) dextrans; and(k) mixtures thereof. 14. A method according to claim 1, wherein the hydrophilic polymer composition comprises polyacrylic acid having a weight average molecular weight of between about 50,000 and about 4,000,000 and exhibiting less than 1% cross-linking. 15. A method according to claim 1, wherein the hydrophilic polymer composition comprises poly(maleic acid/methylvinylether) copolymer having a weight average molecular weight of between about 50,000 and about 4,000,000. 16. A method according to claim 1, wherein the composit ion further comprises between about 0.5 wt. % and about 5 wt. % surfactant. 17. A method according to claim 16, wherein the surfactant comprises at least one of an ethoxylated surfactant, a propoxylated surfactant, an ethoxylated-propoxylated surfactant, and a mixture thereof. 18. A method for manufacturing a topical composition precursor comprising melt processing a mixture comprising:(a) hydrophobic polymer composition comprising poly(vinylpyrrolidone/alkylene) polymer, wherein the alkylene group contains at least about 10 carbon atoms;(b) hydrophilic polymer composition comprising at least one of:(i) polyacrylic acid having a weight average molecular weight of at least about 50,000 and exhibiting less than 1% cross-linking;(ii) poly(maleic acid/methylvinylether) copolymer having a weight average molecular weight of at least about 50,000;(iii) starch;(iv) derivatives of starch;(v) cellulose;(vi) derivatives of cellulose;(vii) carboxymethyl cellulose;(viii) polyvinyl alcohol;(ix) cyclodextrins;(x) dextrans;(xi) mixtures thereof; and(c) wherein the functional group parity of the hydrophobic polymer composition and the hydrophilic polymer composition is provided at a ratio of between about 1:1 and 5:1, and the topical composition precursor contains less than about 1 wt. % water. 19. A method according to claim 18, wherein the hydrophobic polymer composition comprises at least different poly(vinylpyrrolidone/alkylene) polymers, wherein the alkylene group of each polymer contains at least about 10 carbon atoms. 20. A method according to claim 19, wherein the at least two different poly(vinylpyrrolidone/alkylene) polymers comprises a first poly(vtnylpyrrolidone/alkylene) polymer and a second poly(vinylpyrrolidone/alkylene) polymer, wherein the first poly(vinylpyrrolidone/alkylene) polymer is provided at a concentration of between about 5 wt. % and about 54 wt. %, based on the weight of the hydrophobic polymer composition. 21. A method according to claim 18, wherein the hydrophilic polymer composition comprises polyacrylic acid having a weight average molecular weight of between about 50,000 and about 4,000,000. 22. A method according to claim 18, wherein the poly(maleic acid/methylvinylether) copolymer has a weight average molecular weight of between about 50,000 and 4,000,000. 23. A method according to claim 18, wherein the poly(vinylpyrrolidone/alkylene) polymer comprises poly(vinylpyrrolidone/1-eicosene). 24. A method according to claim 18, wherein the poly(vinylpyrrolidone/alkylene) polymer comprises poly(vinypyrrolidone/hexadecene). 25. A method according to claim 18, wherein the functional group parity of the hydrophobic polymer composition to the hydrophilic polymer composition is provided at a ratio of between about 1.5:1 and about 3:1. 26. A method according to claim 18, wherein the hydrophobic polymer composition is provided at a concentration of between about 72 wt. % and about 98 wt. %, and the hydrophilic polymer composition is provided at a concentration of between about 2 wt. % and about 25 wt. %, based on the weight of the topical composition precursor.