초록 ▼

A single-use applicator assembly for dispensing and applying a polymerizable monomeric adhesive material includes: a base portion having at least one sealed compartment; a polymerizable monomeric adhesive material contained in the compartment; an applicator at least partially disposed in the compart

A single-use applicator assembly for dispensing and applying a polymerizable monomeric adhesive material includes: a base portion having at least one sealed compartment; a polymerizable monomeric adhesive material contained in the compartment; an applicator at least partially disposed in the compartment such that a tip of the applicator is proximate the adhesive material. The at least one sealed compartment may comprise first and second sealed compartments that are separated with the polymerizable monomeric adhesive material contained in the first compartment and the applicator at least partially disposed in the second compartment. Alternatively, the first and second compartments may be open to each other. In such case, the applicator assembly may further comprise a plunger that defines the second compartment and that is movable into the first compartment to displace the adhesive material into the second compartment. A kit can include multiple applicator assemblies that are separate or frangibly connected.

대표청구항 ▼

1. A single-use applicator assembly for dispensing and applying a polymerizable monomeric adhesive material, comprising:a base portion having at least one sealed compartment;a polymerizable monomeric adhesive material contained in the at least one compartment; andan applicator at least partially dis

1. A single-use applicator assembly for dispensing and applying a polymerizable monomeric adhesive material, comprising:a base portion having at least one sealed compartment;a polymerizable monomeric adhesive material contained in the at least one compartment; andan applicator at least partially disposed in the at least one compartment such that a tip of the applicator is proximate the polymerizable monomeric adhesive material;wherein removal of at least one of the applicator and the adhesive material requires the applicator assembly to be destructively unsealed; andwherein the base portion is formed from a material that stabilizes the polymerizable monomeric adhesive material in the absence of stabilizers being added to the adhesive material. 2. The applicator assembly according to claim 1, wherein the base portion is formed from a halogenated polymeric material. 3. The applicator assembly according to claim 2, wherein the halogenated polymeric material is selected from the group consisting of polyolefins, halogenated hydrocarbons, and engineered resins. 4. The applicator assembly according to claim 2, wherein the halogenated polymeric material is a fluorinated polymeric material. 5. The applicator assembly according to claim 1, wherein the tip of the applicator comprises a material selected from the group consisting of metal, glass, paper, ceramics and cardboard. 6. The applicator assembly according to claim 1, wherein the tip of the applicator comprises a plastic material. 7. The applicator assembly according to claim 1, wherein the tip of the applicator comprises one of a rolling ball, a brush, and a swab. 8. The applicator assembly according to claim 1, wherein the adhesive material is sterilized. 9. The applicator assembly according to claim 8, wherein the tip of the applicator is sterilized. 10. The applicator assembly according to claim 1, wherein the sealed compartment maximizes a ratio of a surface area of an enclosed space of the sealed compartment to a volume of the adhesive material contained therein. 11. A method of applying an adhesive material, comprising:destructively opening an applicator assembly according to claim 1;removing the applicator from the at least one compartment; anddirectly applying the adhesive to a substrate to be bonded. 12. The method of claim 11, wherein the substrate to be bonded is tissue. 13. A single-use applicator assembly for dispensing and applying a polymerizable monomeric adhesive material, comprising:a base portion having at least one sealed compartment;a polymerizable monomeric adhesive material contained in the at least one compartment; andan applicator at least partially disposed in the at least one compartment such that a tip of the applicator is proximate the polymerizable monomeric adhesive material;wherein the applicator assembly is destructively unsealed by removal of the applicator; andwherein at least the portion of the applicator that is disposed in the compartment is formed from a material that stabilizes the polymerizable monomeric adhesive material. 14. The applicator assembly according to claim 13, wherein the tip of the applicator is made from a same material as the base portion. 15. The applicator assembly according to claim 13, wherein the tip of the applicator is at least one of porous, absorbent and adsorbent in nature. 16. The applicator assembly according to claim 15, wherein the adhesive material is absorbed or adsorbed into the applicator tip. 17. The applicator assembly according to claim 15, wherein a medicament is absorbed or adsorbed into the applicator tip. 18. The applicator assembly according to claim 13, wherein the at least one sealed compartment comprises a first compartment and a second compartment, the first and second compartments being open to each other, the polymerizable monomeric adhesive material being contained in the first compartment and the applicator being at least partially disposed in the second compartment. 19. A method of applyin g an adhesive material, comprisingdestructively opening an applicator assembly according to claim 13;removing the applicator from the at least one compartment; andapplying the adhesive to a substrate to be bonded. 20. The method of claim 19, wherein the substrate to be bonded is tissue. 21. A single-use applicator assembly for dispensing and applying a polymerizable monomeric adhesive material, comprising:a base portion having at least one sealed compartment;a polymerizable monomeric adhesive material contained in the at least one compartment; andan applicator at least partially disposed in the at least one compartment such that a tip of the applicator is proximate the polymerizable monomeric adhesive material;wherein removal of the applicator requires the at least one sealed compartment containing the polymerizable monomeric adhesive material to be destructively unsealed; andwherein the at least one sealed compartment comprises a first sealed compartment and a second sealed compartment, the first and second compartments being separated, the polymerizable monomeric adhesive material being contained in the first compartment and the applicator being at least partially disposed in the second compartment. 22. The applicator assembly according to claim 21, further comprising a polymerization initiator or accelerator for the adhesive material disposed in the second compartment. 23. The applicator assembly according to claim 22, wherein the polymerization initiator or accelerator is disposed in or on the tip of the applicator. 24. The applicator assembly according to claim 23, wherein the tip of the applicator is at least one of porous, absorbent and adsorbent in nature. 25. The applicator assembly according to claim 24, wherein the polymerization initiator or accelerator is absorbed or adsorbed into the tip of the applicator. 26. The applicator assembly according to claim 21, further comprising a medicament disposed in the second compartment. 27. The applicator assembly according to claim 26, wherein medicament is disposed in or on the tip of the applicator. 28. The applicator assembly according to claim 26, wherein the tip of the applicator is at least one of porous, absorbent and adsorbent in nature. 29. The applicator assembly according to claim 28, wherein the medicament is absorbed or adsorbed into the tip of the applicator. 30. A method of applying an adhesive material, comprising:destructively opening an applicator assembly according to claim 21;removing the applicator from the second compartment;applying adhesive to the applicator; andapplying the adhesive to a substrate to be bonded. 31. The method of claim 30, wherein the substrate to be bonded is tissue. 32. A single-use applicator assembly for dispensing and applying a polymerizable monomeric adhesive material, comprising:a base portion having at least one sealed compartment;a polymerizable monomeric adhesive material contained in the at least one compartment; andan applicator at least partially disposed in the at least one compartment such that a tip of the applicator is proximate the polymerizable monomeric adhesive material;wherein removal of at least one of the applicator and the adhesive material requires the applicator assembly to be destructively unsealed; andwherein the at least one sealed compartment comprises a first sealed compartment and a second sealed compartment, the first and second compartments being separated by a frangible barrier separating the first and second compartments, the polymerizable monomeric adhesive material being contained in the first compartment and the applicator being at least partially disposed in the second compartment. 33. A method of applying an adhesive material, comprising:providing an applicator assembly according to claim 32;moving the applicator to break the frangible partition separating the first and second compartments;applying adhesive to the applicator;removing the applicator from the applicator assembly; andapplying the adhesive to a substrate to be bonded. 34. The method of claim 33, wherein the substrate to be bonded is tissue. 35. A single-use applicator assembly for dispensing and applying a polymerizable monomeric adhesive material, comprising:a base portion having at least one sealed compartment;a polymerizable monomeric adhesive material contained in the at least one compartment; andan applicator at least partially disposed in the at least one compartment such that a tip of the applicator is proximate the polymerizable monomeric adhesive material;wherein the applicator assembly is destructively unsealed by removal of the applicator;wherein the at least one sealed compartment comprises a first compartment and a second compartment, the first and second compartments being open to each other, the polymerizable monomeric adhesive material being contained in the first compartment and the applicator being at least partially disposed in the second compartment; anda plunger that defines the second compartment and that is movable into the first compartment to displace the adhesive material into the second compartment. 36. The applicator assembly according to claim 35, further comprising a polymerization initiator or accelerator for the adhesive material disposed in the second compartment. 37. The applicator assembly according to claim 36, wherein the polymerization initiator or accelerator is disposed in or on the tip of the applicator. 38. The applicator assembly according to claim 37, wherein the tip of the applicator is at least one of porous, absorbent and adsorbent in nature. 39. The applicator assembly according to claim 38, wherein the polymerization initiator or accelerator is absorbed or adsorbed into the tip of the applicator. 40. A method of applying an adhesive material, comprising:providing an applicator assembly according to claim 35;moving the plunger into the first compartment to displace the adhesive material into the second compartment such that adhesive is applied to the applicator;removing the applicator from the second compartment; andapplying the adhesive to a substrate to be bonded. 41. The method of claim 40, wherein the substrate to be bonded is tissue. 42. A kit comprising:a plurality of associated single-use applicator assemblies for dispensing and applying a polymerizable monomeric adhesive material, each of the assemblies comprising:a base portion having at least one sealed compartment;a polymerizable monomeric adhesive material contained in the at least one compartment; andan applicator at least partially disposed in the at least one compartment such that a tip of the applicator is proximate the polymerizable monomeric adhesive material;wherein the applicator assembly is destructively unsealed by removal of the applicator; andwherein a first of the assemblies comprises a greater amount of adhesive material than a second of the assemblies. 43. The kit of claim 38, further comprising a medicament contained in the at least one compartment. 44. The kit of claim 42, further comprising a polymerization initiator or accelerator for the adhesive material. 45. The kit of claim 42, wherein at least two of the assemblies are frangibly connected to each other. 46. A kit comprising:a plurality of associated single-use applicator assemblies for dispensing and applying a polymerizable monomeric adhesive material, each of the assemblies comprising:a base portion having at least one sealed compartment;a polymerizable monomeric adhesive material contained in the at least one compartment;an applicator at least partially disposed in the at least one compartment such that a tip of the applicator is proximate the polymerizable monomeric adhesive material; anda polymerization initiator or accelerator for the adhesive material;wherein the applicator assembly is destructively unsealed by removal of the applicator; andwherein a first of the assemblies comprises a greater amount of polymerization initiator or accelerator than a second of the assemblies. 47. A kit comprising:a plurality of associated single-use applicator assemblies for dispensing and applying a polymerizable monomeric adhesive material, each of the assemblies comprising:a base portion having at least one sealed compartment;a polymerizable monomeric adhesive material contained in the at least one compartment;an applicator at least partially disposed in the at least one compartment such that a tip of the applicator is proximate the polymerizable monomeric adhesive material; anda polymerization initiator or accelerator for the adhesive material;wherein the applicator assembly is destructively unsealed by removal of the applicator; andwherein a first of the assemblies comprises a larger sized tip of the applicator than a second of the assemblies. 48. A method of applying an adhesive material, comprising:destructively opening an applicator assembly for dispensing and applying a polymerizable monomeric adhesive material, the applicator assembly comprising:a base portion having at least one sealed compartment;a polymerizable monomeric adhesive material contained in the at least one compartment; andan applicator at least partially disposed in the at least one compartment such that a tip of the applicator is proximate the polymerizable monomeric adhesive material;wherein the applicator assembly is destructively unsealed by removal of the applicator;removing the applicator from the at least one compartment; andapplying the adhesive to a substrate to be bonded;wherein the destructively opening step comprises at least partially separating a first part of the base portion from a second part of the base portion. 49. A method of applying an adhesive material, comprising:destructively opening a single-use applicator assembly for dispensing and applying a polymerizable monomeric adhesive material, the assembly comprising:a base portion having at least one sealed compartment;a polymerizable monomeric adhesive material contained in the at least one compartment; andan applicator at least partially disposed in the at least one compartment such that a tip of the applicator is proximate the polymerizable monomeric adhesive material;wherein the applicator assembly is destructively unsealed by removal applicator;removing the applicator from the at least one compartment; andapplying the adhesive to a substrate to be bonded;wherein the destructively opening step comprises breaking at least a frangible barrier that seals the at least one compartment. 50. A method of applying an adhesive material, comprising:destructively opening a single-use applicator assembly for dispensing and applying a polymerizable monomeric adhesive material, the assembly comprising:a base portion having at least one sealed compartment;a polymerizable monomeric adhesive material contained in the at least one compartment; andan applicator at least partially disposed in the at least one compartment such that a tin of the applicator is proximate the polymerizable monomeric adhesive material;wherein removal of at least one of the applicator and the adhesive material requires the applicator assembly to be destructively unsealed; andwherein the base portion is formed from a material that stabilizes the polymerizable monomeric adhesive material;removing the applicator from the at least one compartment; anddirectly applying the adhesive to a substrate to be bonded;wherein the destructively opening step comprises at least partially separating a first part of the base portion from a second part of the base portion. 51. A method of applying an adhesive material, comprising:destructively opening a single-use applicator assembly for dispensing and applying a polymerizable monomeric adhesive material, the assembly comprising:a base portion having at least one sealed compartment;a polymerizable monomeric adhesive material contained in the at least one compartment; andan applicator at least partially disposed in the at least one compartment such that a tip of the ap plicator is proximate the polymerizable monomeric adhesive material;wherein removal of at least one of the applicator and the adhesive material requires the applicator assembly to be destructively unsealed; andwherein the base portion is formed from a material that stabilizes the polymerizable monomeric adhesive material;removing the applicator from the at least one compartment; anddirectly applying the adhesive to a substrate to be bonded;wherein the destructively opening step comprises breaking at least a frangible barrier that seals the at least one compartment.