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Compositions and methods for the pulmonary delivery of aerosolized macromolecules

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-009/00
  • A61K-009/12
  • A61K-009/14
출원번호 US-0072430 (2002-02-08)
발명자 / 주소
  • Platz, Robert M.
  • Patton, John S.
  • Foster, Linda
  • Eljamal, Mohammed
출원인 / 주소
  • Nektar Therapeutics
대리인 / 주소
    Wilson Mark A.
인용정보 피인용 횟수 : 60  인용 특허 : 136

초록

According to the subject invention, dispersible dry powder pharmaceutical-based compositions are provided, including methods for their manufacture and dry powder dispersion devices. A dispersible dry powder pharmaceutical-based composition is one having a moisture content of less than about 10% by w

대표청구항

1. An aerosolizable, spray-dried powder formulation for pulmonary delivery comprising a FSH, wherein the powder formulation (i) is substantially free of penetration enhancers, and (ii) comprises a plurality of particles having a particle size of less than 10 microns MMD wherein the formulation is fr

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