초록 ▼

A system and method for providing diagnosis and monitoring of myocardial ischemia for use in automated patient care is described. At least one recorded physiological measure is compared to at least one other recorded physiological measure on a substantially regular basis to quantify a change in pati

A system and method for providing diagnosis and monitoring of myocardial ischemia for use in automated patient care is described. At least one recorded physiological measure is compared to at least one other recorded physiological measure on a substantially regular basis to quantify a change in patient pathophysiological status for equivalent patient information. An absence, an onset, a progression, a regression, and a status quo of myocardial ischemia is evaluated dependent upon the change in patient pathophysiological status.

대표청구항 ▼

1. A system for providing diagnosis and monitoring of myocardial ischemia for use in automated patient care, comprising:an implantable medical device recording at least one physiological measure and at least one other physiological measure on a substantially continuous basis;a database storing monit

1. A system for providing diagnosis and monitoring of myocardial ischemia for use in automated patient care, comprising:an implantable medical device recording at least one physiological measure and at least one other physiological measure on a substantially continuous basis;a database storing monitoring sets comprising the at least one recorded physiological measure and the at least one other recorded physiological measure;a comparison module comparing the at least one recorded physiological measure to the at least one other recorded physiological measure on a substantially regular basis to quantify a change in patient pathophysiological status for corresponding patient information; a diagnostic module comparing the change in patient pathophysiological status to an indicated threshold corresponding to a quantifiable physiological measure indicative of myocardial ischemia; andan analysis module evaluating an onset, a progression, a regression, and a status quo of myocardial ischemia dependent upon the comparison of the patient pathophysiological status to the indicator threshold. 2. A system according to claim 1, further comprising:a database module retrieving the at least one recorded physiological measure and the at least one other recorded physiological measure from at least one of the monitoring sets stored in the database. 3. A system according to claim 2, further comprising:a server system collecting the at least one recorded physiological measure and the at least one other recorded physiological measure into each monitoring set recorded on a substantially continuous basis or derived therefrom. 4. A system according to claim 3, further comprising:an external medical device recording the at least one recorded physiological measure and the at least one other recorded physiological measure. 5. A system according to claim 1, further comprising:the analysis module evaluating an absence, an onset, a progression, a regression, and a status quo of diseases other than myocardial ischemia dependent upon the change in patient pathophysiological status. 6. A system according to claim 1, wherein the monitoring sets further comprise at least one quality of life measure and at least one other quality of life measure, further comprising:a diagnostic module comparing the at least one recorded quality of life measure to the at least one other recorded quality of life measure on a substantially regular basis to qualify a change in patient pathophysiological status. 7. A system according to claim 1, further comprising:a stickiness indicator defined for the at least one physiological measure corresponding to a temporal boundary on one of patient diagnosis and treatment;a diagnostic module timing each change in patient pathophysiological status for corresponding patient information and determining one of a revised patient diagnosis and treatment responsive to each change in patient pathophysiological status with a timing exceeding the stickiness indicator. 8. A system according to claim 1, wherein the monitoring sets further comprise a reference baseline, further comprising:a diagnostic module comparing the change in patient pathophysiological status to the reference baseline comprising recorded physiological measures recorded during an initial time period. 9. A system according to claim 1, further comprising:a diagnostic module comparing the change in patient pathophysiological status to patient information corresponding to at least one of an individual patient, a peer group, and a overall patient population. 10. A system according to claim 1, further comprising:a diagnostic module grading the change in patient pathophysiological status on a fixed scale based on a degree of deviation from a pre-defined indicator threshold and performing a summation over a plurality of the graded changes to determine an overall change in patient pathophysiological status. 11. A system according to claim 1, further comprising:a diagnostic module determining p robabilistic weightings of the change in patient pathophysiological status on a statistical deviation and trends via linear fits from a pre-defined indicator threshold and performing a summation over a plurality of the probabilistic weightings to determine an overall change in patient pathophysiological status. 12. A method for providing diagnosis and monitoring of myocardial ischemia for use in automated patient care, comprising:recording at least one physiological measure and at least one other physiological measure on a substantially continuous basis with an implantable medical device;storing monitoring sets comprising the at least one recorded physiological measure and the at least one other recorded physiological measure;comparing the at least one recorded physiological measure to the at least one other recorded physiological measure on a substantially regular basis to quantify a change in patient pathophysiological status for corresponding patient information; comparing the change in patient pathophysiological status to an indicator threshold corresponding to a quantifiable physiological measure indicative of myocardial ischemia; andevaluating an onset, a progression, a regression, and a status quo of myocardial ischemia dependent upon the comparison of the patient pathophysiological status to the indicator threshold. 13. A method according to claim 12, further comprising:retrieving the at least one recorded physiological measure and the at least one other recorded physiological measure from at least one of the monitoring sets stored in the database. 14. A method according to claim 13, further comprising:collecting the at least one recorded physiological measure and the at least one other recorded physiological measure into each monitoring set recorded on a substantially continuous basis or derived therefrom. 15. A method according to claim 14, further comprising:recording the at least one recorded physiological measure and the at least one other recorded physiological measure with an external medical device. 16. A method according to claim 12, further comprising:evaluating an absence, an onset, a progression, a regression, and a status quo of diseases other than myocardial ischemia dependent upon the change in patient pathophysiological status. 17. A method according to claim 12, wherein the monitoring sets further comprise at least one quality of life measure and at least one other quality of life measure, further comprising:comparing the at least one recorded quality of life measure to the at least one other recorded quality of life measure on a substantially regular basis to qualify a change in patient pathophysiological status. 18. A method according to claim 12, further comprising:defining a stickiness indicator for the at least one physiological measure corresponding to a temporal boundary on one of patient diagnosis and treatment;timing each change in patient pathophysiological status for corresponding patient information; anddetermining one of a revised patient diagnosis and treatment responsive to each change in patient pathophysiological status with a timing exceeding the stickiness indicator. 19. A method according to claim 12, wherein the monitoring sets further comprise a reference baseline, further comprising:comparing the change in patient pathophysiological status to the reference baseline comprising recorded physiological measures recorded during an initial time period. 20. A method according to claim 12, further comprising:comparing the change in patient pathophysiological status to patient information corresponding to at least one of an individual patient, a peer group, and a overall patient population. 21. A method according to claim 12, further comprising:grading the change in patient pathophysiological status on a fixed scale based on a degree of deviation from a pre-defined indicator threshold; andperforming a summation over a plurality of the graded changes to determine an overall change in patie nt pathophysiological status. 22. A method according to claim 12, further comprising:determining probabilistic weightings of the change in patient pathophysiological status on a statistical deviation and trends via linear fits from a pre-defined indicator threshold; andperforming a summation over a plurality of the probabilistic weightings to determine an overall change in patient pathophysiological status. 23. A computer-readable storage medium for a device holding code for performing the method according to claim 12.