IPC분류정보
국가/구분 |
United States(US) Patent
등록
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국제특허분류(IPC7판) |
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출원번호 |
US-0894857
(2001-06-27)
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발명자
/ 주소 |
- Lee, Michael
- Worthington, Gajus
- Harris, Gregory
- Montgomery, James
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출원인 / 주소 |
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대리인 / 주소 |
Townsend and Townsend and Crew LLP
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인용정보 |
피인용 횟수 :
111 인용 특허 :
14 |
초록
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The present invention generally relates to microfluidics and more particularly to the design of customized microfluidic systems using a microfluidic computer aided design system. In one embodiment of the present invention a microfluidic circuit design method is provided. The method includes developi
The present invention generally relates to microfluidics and more particularly to the design of customized microfluidic systems using a microfluidic computer aided design system. In one embodiment of the present invention a microfluidic circuit design method is provided. The method includes developing synthesizable computer code for a design. Next, a microfluidic circuit schematic, including a plurality of symbols for microfluidic components, is generated either interactively or using the synthesizable computer code. The microfluidic circuit schematic is then functionally simulated. The microfluidic components are placed and routed on a template to form a physical layout. Then the physical layout is physically simulated using dynamic simulation models of the microfluidic components; and the physical layout is written to a layout file.
대표청구항
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1. A method, using a computer system, for physically laying out a microfluidic circuit comprising a plurality of microfluidic components, said method comprising:selecting a template;placing a first component of said plurality of microfluidic components on said template, wherein said plurality of mic
1. A method, using a computer system, for physically laying out a microfluidic circuit comprising a plurality of microfluidic components, said method comprising:selecting a template;placing a first component of said plurality of microfluidic components on said template, wherein said plurality of microfluidic components each have an associated property;placing a second component of said plurality of microfluidic components on said template; andconnecting said first component to said second componentwherein said associated property has at least one of physical scaling, physical property, layer assignment, and functional definition and said physical property includes a physical dimension having depth information. 2. The method of claim 1 wherein said physical property includes an element attribute. 3. A method, using a computer system, for physically laying out a microfluidic circuit comprising a plurality of microfluidic components, said method comprising:selecting a template;placing a first component of said plurality of microfluidic components on said template, wherein said plurality of microfluidic components each have an associated property;placing a second component of said plurality of microfluidic components on said template; andconnecting said first component to said second componentwherein said associated property has at least one of physical scaling, physical property, layer assignment and functional definition, wherein said first component comprises an elastomeric structure. 4. The method of claim 3 wherein said elastomeric structure is formed by bonding together a plurality of layers of elastomer. 5. The method of claim 3 wherein said elastomeric structure is formed in part by depositing a photoresist layer on top of an elastomeric layer. 6. The method of claim 3 wherein each component of said plurality of components includes a representative symbol. 7. The method of claim 3 wherein said first component comprises a control channel which moves an associated rigid silicon material, and a fluid channel formed from an elastomeric material. 8. The method of claim 3 wherein said first component functions as a NAND gate. 9. The method of claim 3 wherein said plurality of microfluidic components include channels, pumps, valves, chambers, cell sorters, DNA fingerprint macros, multiplexers, bridges, pressure oscillators, and layer interconnects. 10. The method of claim 3 wherein said plurality of microfluidic components comprise a structure made from a material selected from the group consisting of a flexible material, a rigid material, or a mixture of rigid and flexible materials. 11. The method of claim 3 wherein said rigid material is a silicon based material. 12. The method of claim 3 wherein said flexible material is an elastomer based material. 13. The method of claim 3 wherein said first component comprises a first control channel and a first fluid channel, said second component comprises a second control channel and a second fluid channel, and said connecting comprises connecting said first fluid channel to said second fluid channel. 14. The method of claim 13 wherein when said first component is on a first fluid layer and said second component is on a second fluid layer, said first fluid channel being connected to said second fluid channel by a via. 15. The method of claim 13 wherein said first control channel is on a control layer and said first fluid channel is on a fluid layer. 16. The method of claim 15 wherein said control layer is separate from said fluid layer. 17. The method of claim 13 wherein said first fluid channel is connected to said second fluid channel by a third fluid channel and wherein when said first control channel is connected to a third control channel that crosses said third fluid channel, said third control channel uses an interconnect bridge to cross said third fluid channel. 18. The method of claim 17 wherein said third fluid channel is reduced in width at and near where said third control channel crosses said third fluid channel. 19. The method of claim 3 wherein said first component comprises a first control channel and a first fluid channel, said second component comprises a second control channel and a second fluid channel, and said connecting comprises connecting said first control channel to said second control channel. 20. The method of claim 3 wherein said connecting comprises auto-routing. 21. The method of claim 3 wherein said connecting comprises routing. 22. The method of claim 3 wherein said connecting comprises a design rule check. 23. A microfluidic circuit physical layout method, using a computer, comprising:selecting a template comprising an I/O port;placing a microfluidic component on said template, wherein said microfluidic component comprises a component control channel and a component fluid channel; andconnecting said component control channel to said I/O port. 24. The method of claim 23 wherein said microfluidic component includes an elastomeric structure. 25. The method of claim 23 wherein said connecting includes using a control channel to connect said component control channel to said I/O port. 26. The method of claim 23 further comprising:placing another microfluidic component on said template; andconnecting said component fluid channel of said microfluidic component to another component fluid channel of said another microfluidic component. 27. A method for physical layout of a microfluidic system, said microfluidic system comprising a plurality of microfluidic components, said method comprising:placing a component of said plurality of microfluidic components on a first layer of a plurality of layers, said component comprising a first fluid channel and a first control channel;placing a second fluid channel on a second layer of said plurality of layers; andconnecting said first fluid channel to said second fluid channel using a via. 28. A method for physical layout of a microfluidic system using a computer aided design tool, said microfluidic system comprising a plurality of microfluidic components, said method comprising:selecting a template, comprising a plurality of layers;placing a first symbol representing a first component of said plurality of microfluidic components, said first symbol comprising a first fluid channel symbol and a first control channel symbol, said first control channel symbol on a different layer of said plurality of layers than said first fluid channel symbol;placing a second symbol representing a second component of said plurality of microfluidic components, said second symbol comprising a second fluid channel symbol; andconnecting said first fluid channel symbol to said second fluid channel symbol. 29. The method of claim 28 wherein said template comprises an I/O port and said first symbol comprises a first control channel symbol, said method further comprising connecting said first control channel symbol to said I/O port. 30. The method of claim 28 wherein said plurality of microfluidic components are selected from the group consisting of logic gates, channels, pumps, valves, oscillators, chambers, and layer interconnects. 31. The method of claim 28 wherein symbols are connected according to preset design rules. 32. The method of claim 28 wherein said plurality of microfluidic components are assigned physical scaling. 33. The method of claim 28 wherein said plurality of microfluidic components are assigned physical properties. 34. The method of claim 28 wherein said first component is an active fluidic component. 35. The method of claim 28 wherein symbols of components of said plurality of microfluidic components are placed automatically based on preset design rule constraints. 36. The method of claim 28 wherein symbols of components of said plurality of microfluidic components are placed interactively. 37. The method of claim 28 wherein symbols of components of said plurality of microfluidic components are placed manually subject to predetermined design rule checks. 38. The method of claim 28 wherein said predetermined design rule checks include one or more of the checks on I/O placement, channel size mismatch, dangling channels, overlapping components and channels, and channel spacing. 39. The method of claim 28 wherein the components are placed based on mechanical properties. 40. The method of claim 28 wherein said first symbol is connected to said second symbol automatically using an auto-routing routine. 41. The method of claim 28 wherein said first symbol is routed to said second symbol interactively. 42. The method of claim 28 wherein said first symbol is connected to said second symbol manually using a computer display. 43. A computer program product stored in a computer readable medium for physically laying-out a microfluidic circuit comprising a plurality of microfluidic components, said computer program product comprising:code for selecting a template; code for placing a first component of said plurality of microfluidic components on said template, wherein said plurality of microfluidic components comprise multilayered components;code for placing a second component of said plurality of microfluidic components on said template; andcode for connecting said first component to said second component wherein the microfluidic component of said microfluidic components comprises a data structure having channel depth information.
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