Sterile fluid pumping or mixing system and related method
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
B01F-01308
H01L-03900
B04F-01700
출원번호
US-0120006
(2002-04-10)
발명자
/ 주소
Terentiev, Alexandre N.
출원인 / 주소
Levtech, Inc.
대리인 / 주소
King &
인용정보
피인용 횟수 :
12인용 특허 :
28
초록▼
A system for pumping or mixing a fluid using a levitating, rotating magnetic element and various other components for use in a pumping or mixing system are disclosed. The magnetic element is placed in a vessel or container that can be positioned in close proximity to a superconducting element. The v
A system for pumping or mixing a fluid using a levitating, rotating magnetic element and various other components for use in a pumping or mixing system are disclosed. The magnetic element is placed in a vessel or container that can be positioned in close proximity to a superconducting element. The vessel or container may be sealed with the magnetic element and a product therein, with the fluid being introduced after sealing. Preferably, the vessel or container is capable of holding fluid volumes greater than 10 liters.
대표청구항▼
1. A fluid pumping or mixing system, comprising:a vessel or container for holding a fluid and a product; a magnetic element capable of providing a pumping or mixing action to the fluid upon rotation; at least one superconducting element for levitating said magnetic element in the vessel or container
1. A fluid pumping or mixing system, comprising:a vessel or container for holding a fluid and a product; a magnetic element capable of providing a pumping or mixing action to the fluid upon rotation; at least one superconducting element for levitating said magnetic element in the vessel or container; a wall defining a chamber around the superconducting element, said chamber thermally isolating the superconducting element from the vessel or container; a cooling source thermally linked to said superconducting element; a motive device for rotating said superconducting element. 2. The system for pumping or mixing a fluid according to claim 1, wherein the chamber is evacuated or insulated to minimize thermal transfer from said superconducting element to said wall and provide the desired thermal isolation.3. The system for pumping or mixing a fluid according to claim 1, wherein said wall is the outer wall of a cryostat and said cooling source is a chamber in said cryostat holding a liquid cryogen.4. The system for pumping or mixing a fluid according to claim 1, wherein said cooling source is a refrigerator.5. The system for pumping or mixing a fluid according to claim 1, wherein said superconducting element is supported by the wall defining said chamber, and wherein said chamber is in turn supported from a stable mounting structure by a bearing permitting rotational motion, said motive device rotating said wall and said superconducting element together.6. The system for pumping or mixing a fluid according to claim 5, wherein said cooling source is coupled to and rotates with said wall.7. The system according to claim 1, wherein the product is selected from the group consisting of a bacterial nutrient culture media, eukaryotic cell nutrient culture media, buffer, reagent, and the like.8. The system according to claim 1, wherein the product is introduced into the vessel in a dry, powder-like form and the fluid is introduced either before or after the magnetic element is in a levitated state.9. The system according to claim 1, wherein the vessel is substantially sealed prior to the levitation of the magnetic element, but includes a sterile fitting for introducing or extracting the fluid, product, or both therefrom.10. The system according to claim 1, wherein the vessel and magnetic element are sterilized prior to introduction of the fluid.11. The system for pumping or mixing a fluid according to claim 1, wherein the vessel is capable of holding a volume of fluid of about 10 liters or greater.12. A method of mixing a fluid in a vessel or container, comprising:placing a magnetic pumping or mixing element and a product in the vessel or container; substantially sealing the vessel or container from the outside environment; levitating the magnetic element above a superconducting element positioned in an evacuated or insulated chamber adjacent to the vessel or container and thermally linked to a cooling source; and rotating the superconducting element. 13. The method according to claim 12, further including cleaning or sterilizing both the vessel or container and the magnetic element prior to the sealing step.14. The method according to claim 12, further including placing the product in the vessel prior to the sealing step.15. The method according to claim 12, wherein the substantially sealed vessel includes at least one sterile or aseptic fitting, and further including the step of introducing the fluid into the vessel after the sealing step through the fitting, whereby a sterile or aseptic mixing environment is created.
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이 특허에 인용된 특허 (28)
Meier Hans P. (Jona CHX), Double impeller for stirring sterile liquids.
Herrmann Peter F. (Dourdan Corbreuse FRX) Beghin Erick (Massy FRX) Cottevieille Christian (Montreuil FRX), Lead-in module for the supply of a low critical temperature superconducting electric load.
Terentiev Alexander N. (Kingston CAX) Harrison John P. (Kingston CAX), Method and apparatus for damping mechanical vibration with a high Tc superconductor.
Rosenbaum Larry A. ; Anderson William ; Woo Lecon ; Laurin Dean ; Buan Angeles Lillian ; Ling Michael T. K. ; Ding Yuan Pang Samuel ; Hayward Denise S. ; Hoppesch Joseph P. ; Nebgen Gregg ; Westphal , Multi-layered polymer based thin film structure for medical grade products.
Rosenbaum Larry A. ; Anderson William ; Woo Lecon ; Laurin Dean ; Buan Angeles Lillian ; Ling Michael T.K. ; Ding Yuan Pang Samuel ; Hayward Denise S. ; Hoppesch Joseph P. ; Nebgen Gregg ; Westphal S, Multi-layered polymer structure for medical products.
Haber Terry M. (Lake Forest CA) Foster Clark B. (Laguna Niguel CA) Smedley William H. (Lake Elsinore CA), Pharmaceutical mixing container with rotatable vaned internal magnetic mixing element.
Larsson Ake (Tokyo JPX) Uno Kiyoshi (Shiga JPX), Process for preparing a stock solution composition for a medical treatment, and a soft bag having a magnetic stirrer to.
Erdenberger, Thomas; Damren, Richard L.; Tuohey, Colin R.; Fisher, Michael; Galliher, Parrish M.; Kenney, Jonathan A., Single-use mixing and bioreactor systems.
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