IPC분류정보
국가/구분 |
United States(US) Patent
등록
|
국제특허분류(IPC7판) |
|
출원번호 |
US-0373112
(1999-08-11)
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발명자
/ 주소 |
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출원인 / 주소 |
- Innercool Therapies, Inc.
|
대리인 / 주소 |
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인용정보 |
피인용 횟수 :
20 인용 특허 :
129 |
초록
A device and method for providing body cooling. The cooling device applies cooling to blood flowing in a vena cavae that is then distributed throughout the body. The cooling can be assisted by use of thermoregulatory drugs or warming devices to prevent shivering and vasoconstriction.
대표청구항
▼
1. A method for cooling a patient's body intravascularly, comprising:providing a catheter having a cooling element attached to a distal end thereof, the cooling element having mixing-inducing surface features thereon; inserting the catheter through the vascular system of the patient to place the coo
1. A method for cooling a patient's body intravascularly, comprising:providing a catheter having a cooling element attached to a distal end thereof, the cooling element having mixing-inducing surface features thereon; inserting the catheter through the vascular system of the patient to place the cooling element in a vein that drains into the heart of a patient; circulating fluid through the cooling element; transferring heat from the blood in the vein to the cooling element; and administering an antishivering drug to the patient. 2. The method of claim 1, wherein the antishivering drug is selected from the group consisting of clonidine, meperidine, propofol, magnesium, dexmedetomidine, and combinations thereof.3. The method of claim 1, wherein the cooling element is disposed in a vein selected from the group consisting of the superior vena cava, the inferior vena cava, the iliac vein, the femoral vein, or combinations of the above.4. A method for changing a patient's body temperature intravascularly while controlling patient shivering, comprising:providing a catheter having a heat exchange element at a portion thereof; inserting the catheter through the vascular system of the patient to place the heat exchange element in a blood vessel; circulating fluid through the heat exchange element; transferring heat from the blood in the vessel to the heat exchange element; and administering an antishivering drug to the patient. 5. The method of claim 4, wherein the antishivering drug is selected from the group consisting of clonidine, meperidine, propofol, magnesium, dexmedetomidine, and combinations thereof.6. A method for cooling a patient's body intravascularly, comprising:determining a target hypothermic temperature to be achieved; providing a catheter having a cooling element attached to a distal end thereof; inserting the catheter through the vascular system of the patient to place the cooling element in a vein that drains into the heart of a patient; circulating fluid through the cooling element; monitoring the patient temperature with a temperature probe; transferring heat from the blood in the vein to the cooling element and controlling the temperature of the patient so that the target temperature is substantially reached and so that the maximum temperature differential between the blood stream and the cooling element is limited to approximately 32° C.; and administering an antishivering drug to the patient. 7. The method of claim 6, further comprising inducing mixing in the blood stream.8. The method of claim 6, wherein the antishivering drug is selected from the group consisting of clonidine, meperidine, propofol, magnesium, dexmedetomidine, and combinations thereof.9. A method for cooling a patient's body intravascularly, comprising:providing a catheter having a cooling element attached to a distal end thereof, the cooling element having mixing-inducing surface features thereon; inserting the catheter through the vascular system of the patient to place the cooling element in a vein that drains into the heart of a patient; circulating fluid through the cooling element; transferring heat from the blood in the vein to the cooling element; and administering a thermoregulatory drug to the patient with the proviso that the thermoregulatory drug does not include vasodilatory drugs. 10. The method of claim 9, wherein the thermoregulatory drug is selected from the group consisting of clonidine, meperidine, propofol, magnesium, dexmedetomidine, and combinations thereof.11. The method of claim 9, wherein the cooling element is disposed in a vein selected from the group consisting of the superior vena cava, the inferior vena cava, the iliac vein, the femoral vein, or combinations of the above.12. A method for changing a patient's body temperature intravascularly while controlling patient shivering, comprising:providing a catheter having a heat exchange element at a portion thereof; inserting the catheter through the vascular system of the patient to place the heat exchange element in a blood vessel; circulating fluid through the heat exchange element; transferring heat from the blood in the vessel to the heat exchange element; and administering a thermoregulatory drug to the patient with the proviso that the thermoregulatory drug does not include vasodilatory drugs. 13. The method of claim 12, wherein the thermoregulatory drug is selected from the group consisting of clonidine, meperidine, propofol, magnesium, dexmedetomidine, and combinations thereof.14. A method for cooling a patient's body intravascularly, comprising:determining a target hypothermic temperature to be achieved; providing a catheter having a cooling element attached to a distal end thereof; inserting the catheter through the vascular system of the patient to place the cooling element in a vein that drains into the heart of a patient; circulating fluid through the cooling element; monitoring the patient temperature with a temperature probe; transferring heat from the blood in the vein to the cooling element and controlling the temperature of the patient so that the target temperature is substantially reached and so that the maximum temperature differential between the blood stream and the cooling element is limited to approximately 32° C.; and administering a thermoregulatory drug to the patient with the proviso that the thermoregulatory drug does not include vasodilatory drugs. 15. The method of claim 14, further comprising inducing mixing in the blood stream.16. The method of claim 14, wherein the thermoregulatory drug is selected from the group consisting of clonidine, meperdine, propofol, magnesium, dexmedetomidine, and combinations thereof.
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