초록

A container made without employing a mold release agent, comprised of halogenated polymeric material provides an extended shelf-life for 1,1-disubstituted ethylene adhesive monomer compositions.

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1. A combination including:a container comprising a polymeric resin matrix including at least one halogenated polymeric material, the container being free from mold release agent; and a 1,1-disubstituted ethylene monomer composition contained in said container. 2. The combination of claim 1, wherein

1. A combination including:a container comprising a polymeric resin matrix including at least one halogenated polymeric material, the container being free from mold release agent; and a 1,1-disubstituted ethylene monomer composition contained in said container. 2. The combination of claim 1, wherein said halogenated polymeric material is a post-halogenated polymeric material.3. The combination of claim 1, wherein said polymeric material is high-density polyethylene.4. The combination of claim 1, wherein said mold release agent is zinc stearate.5. The combination of claim 1, wherein said container is sterilized.6. The combination of claim 1, wherein said container is sterilized using electron beam radiation.7. The combination of claim 1, wherein said 1,1-disubstituted ethylene monomer composition comprises an alkyl α-cyanoacrylate adhesive monomer having an alkyl carbon length of at least six carbons.8. The combination of claim 7, wherein said alkyl α-cyanoacrylate adhesive monomer is 2-octyl cyanoacrylate.9. The combination of claim 1, wherein said halogenated polymeric material is a post-fluorinated polymeric material.10. A combination including;a container comprising a polymeric resin matrix including at least one halogenated polymeric material, the container being free from zinc stearate; and a 1,1-disubstituted ethylene monomer composition contained in said container. 11. The combination of claim 10, wherein said halogenated polymeric material is a post-halogenated polymeric material.12. The combination of claim 10, wherein said halogenated polymeric material is present on at least an interior surface of said container.13. The combination of claim 10, wherein said halogenated polymeric material is in direct contact with said 1,1-disubstituted ethylene monomer composition.14. The combination of claim 10, wherein said polymeric material is selected from the group consisting of a polyolefin and an engineered resin.15. The combination of claim 14, wherein said polymeric material is high density polyethylene.16. The combination of claim 14, wherein said polymeric material is linear low density polyethylene.17. The combination of claim 16, wherein said polymeric material is polyethylene terephthalate.18. The combination of claim 10, wherein said polymeric material comprises at least one polymer selected from the group consisting of low density polyethylene, linear low density polyethylene, high density polyethylene, cross-linked high density polyethylene, polypropylene, polyethylene terephthalate, polybutylene terephthalate, and oriented polyethylene terephthalate.19. The combination of claim 10, wherein said container is a laminate and a layer comprising said post-halogenated polymeric material is in direct contact with said 1,1-disubstituted ethylene monomer composition.20. The combination of claim 10, wherein said combination has a shelf-life of at least about twenty-four months.21. The combination of claim 10, wherein said combination has a shelf-life of at least about thirty months.22. The combination of claim 10, wherein said container is sterilize.23. The combination of claim 10, wherein said container is sterilized using electron beam radiation.24. The combination of claim 10, wherein said 1,1-disubstituted ethylene monomer composition comprises an alkyl α-cyanoacrylate adhesive monomer having an alkyl carbon length of at least six carbons.25. The combination of claim 24, wherein said allyl α-cyanoacrylate adhesive monomer is 2-octyl cyanoacrylate.26. The combination of claim 25, wherein said container comprises:a body comprising an interior and an exterior surface, wherein said body comprises a post-halogenated high density polyethylene polymer on at least said interior surface; a dispenser nozzle comprising at least an interior surface, wherein said dispenser nozzle comprises a post-halogenated linear low density polyethylene on said interior surface, the dispenser nozzle being free from zinc stearate; and a cap comprising post-halogenated polypropylene, the cap being free from zinc stearate. 27. The combination of claim 10, wherein said halogenated polymeric material is a post-fluorinated polymeric material.28. The combination of claim 10, wherein said halogenated polymeric material is a post-chlorinated polymeric material.29. The combination of claim 10, wherein said halogenated polymeric material comprises a surface region and a sub-surface region, and wherein a halogen concentration in said surface region is greater than a halogen concentration in said sub-surface region.30. A combination including:a container comprising a polymeric resin matrix including fluorinated high-density polyethylene, the container being free from zinc stearate; and a 1,1-disubstituted ethylene monomer composition contained in said container; wherein said container is sterilized using electron beam radiation. 31. A method of manufacturing a polymeric container containing a 1,1-disubstituted ethylene monomer, comprising:providing a container comprising a halogenated polymeric material, said container comprising at least an internal surface and an external surface, the container being free from mold release agent; dispensing a 1,1-disubstituted ethylene monomer composition into said container; optionally sealing said container; and optionally sterilizing said container. 32. The method of claim 31, wherein providing a container comprises providing a container that is free from zinc stearate.33. The method of claim 31, wherein said 1,1-disubstituted ethylene monomer is an alkyl α-cyanoacrylate.34. The method of claim 31, wherein optionally sterilizing comprises sterilizing with electron beam radiation.35. The method of claim 31, wherein said polymeric material is high density polyethylene.36. A method of manufacturing a polymeric container containing a 1,1-disubstituted ethylene monomer, comprising:providing a container comprising a halogenated polymeric material, said container comprising at least an internal surface and an external surface, the container being free from zinc stearate; dispensing a 1,1-disubstituted ethylene monomer composition into said container; optionally sealing said container; and optionally sterilizing said container. 37. The method of claim 36, wherein optionally sterilizing comprises sterilizing with electron beam radiation.38. A method of manufacturing a polymeric container containing a 1,1-disubstituted ethylene monomer, comprising:providing a container comprising a polymeric material, said container comprising at least an internal surface and an external surface, the container being free from zinc stearate; halogenating said polymeric material on at least said internal surface of said container; dispensing a 1,1-disubstituted ethylene monomer composition into said container; optionally sealing said container; and optionally sterilizing said container. 39. The method of claim 38, wherein said halogenating is performed after molding said polymeric material into a form that is to be the form of the container.40. The method of claim 38, wherein said halogenating is performed concurrent with molding said polymeric material into a form that is to be the form of the container.41. The method of claim 40, wherein said molding comprises blow-molding a parison using a halogen-containing gas, and said halogen-containing gas also performs said halogenating.42. The method of claim 41, wherein residual halogen-containing species from said molding remain captured or dissolved in said container and are not removed from said container prior to said dispensing.43. The method of claim 38, wherein said 1,1-disubstituted ethylene monomer is an alkyl α-cyanoacrylate.44. The method of claim 38, wherein said container is sterilized with electron beam radiation.45. The method of claim 38, wherein said halogenating comprises fluorinating said polymeric material on at least said internal surface of said container.46. The method of claim 38, wherein said halogenating comprises chlorinating said polymeric material on at least said internal surface of said container.47. The method of claim 38, wherein said polymeric material is selected from the group consisting of low density polyethylene, linear low density polyethylene, high density polyethylene, cross-linked high density polyethylene, polypropylene, polyethylene terephthalate, polybutylene terephthalate, and oriented polyethylene terephthalate.48. A method of manufacturing a polymeric container containing a 1,1-disubstituted ethylene monomer, comprising:providing a container comprising fluorinated high-density polyethylene, said container comprising at least an internal surface and an external surface, the container being free from zinc stearate; dispensing a 1,1-disubstituted ethylene monomer composition into said container; sealing said container; and sterilizing said container with electron beam radiation. 49. A method of storing a 1,1-disubstituted ethylene monomer composition in a container comprising:providing a container comprising a polymeric resin matrix including at least one halogenated polymeric material, the container being free from zinc stearate; dispensing a 1,1-disubstituted ethylene monomer composition into said container; optionally sterilizing said container; and storing said monomer-containing container for more than one year without failure of the container or monomer composition. 50. The method of claim 49, wherein said storing of said monomer-containing container is for more than twenty-four months without failure of the container or monomer composition.51. The method of claim 49, wherein said storing of said monomer-containing container is for more than thirty months without failure of the container or monomer composition.52. The method of claim 49, wherein said storing is under conditions of room temperature and a relative humidity of from about 40 to about 60%.53. The method of claim 49, wherein said 1,1-disubstituted ethylene monomer composition comprises an alkyl α-cyanoacrylate monomer.54. The method of claim 49, wherein said container is made by a process comprising:providing a container comprising a polymeric material, said container comprising at least an internal surface and an external surface, and halogenating said polymeric material on at least said internal surface of said container. 55. The method of claim 49, further comprising sealing said container prior to said storing step.56. The method of claim 49, wherein optionally sterilizing comprises sterilizing with electron beam radiation.57. The method of claim 49, wherein said container is not enclosed in an external moisture barrier.58. The method of claim 49, wherein said container is not subjected to refrigeration.