초록 ▼

A flexible applicator for applying an oil-in-water emulsion comprises: (1) an allantoin-containing oil-in-water emulsion; and (2) a flexible element that adsorbs or absorbs the emulsion such that the emulsion is applied to the skin of a patient on whom the flexible applicator is placed. The allantoi

A flexible applicator for applying an oil-in-water emulsion comprises: (1) an allantoin-containing oil-in-water emulsion; and (2) a flexible element that adsorbs or absorbs the emulsion such that the emulsion is applied to the skin of a patient on whom the flexible applicator is placed. The allantoin-containing emulsion, containing allantoin and an emulsifier, has improved stability coming from the adjustment of the pH to a range of 3.0 to 6.0; preferably, the pH is in the range of 4.5 to about 5.8. The lower pH preserves the stability of the allantoin and the functionality of the emulsifier system is maintained. The emulsifier system can be a nonionic emulsifier or an anionic emulsifier plus beeswax. The acid used to adjust the pH can be an organic acid or an inorganic acid. The emulsion can further comprise other ingredients such as herbal extracts, chelating agents, preservatives, emollients, solvents, and fragrance. The flexible element can be in the form of a bandage or wipe, and can be formed of a material such as cotton, cellulose, nylon, rayon, a non-woven fabric, or a plastic polymer.

대표청구항 ▼

1. A flexible applicator system for applying an oil-in-water emulsion comprising:(a) an oil-in-water emulsion comprising: (i) water; (ii) sodium lauryl sulfate; (iii) propylene glycol; (iv) tetrasodium EDTA; (v) citric acid; (vi) lanolin oil; (vii) cetyl alcohol; (viii) stearyl alcohol; (ix) beeswax

1. A flexible applicator system for applying an oil-in-water emulsion comprising:(a) an oil-in-water emulsion comprising: (i) water; (ii) sodium lauryl sulfate; (iii) propylene glycol; (iv) tetrasodium EDTA; (v) citric acid; (vi) lanolin oil; (vii) cetyl alcohol; (viii) stearyl alcohol; (ix) beeswax, (x) cod liver oil; (xi) butylated hydroxytoluene; (xii) St. John's wort extract; (xiii) witch hazel extract; (xiv) chamomile extract; (xv) arnica extract; (xvi) methylparaben; (xvii) propylparaben (xviii) over 0.40% of allantoin; and (xix) fragrance; wherein the pH of the emulsion is from about 4.5 to about 5.8, the allantoin being stable in the emulsion for at least 90 days at 40° C.; and(b) a flexible element that adsorbs or absorbs the emulsion such that the emulsion is applied to the skin of a patient on whom the flexible applicator is placed. 2. A flexible applicator system for applying an oil-in-water emulsion comprising:(a) an oil-in-water emulsion comprising: (i) from about 50% to about 90% water; (ii) from about 0.5% to about 2.5% of 30% sodium lauryl sulfate; (iii) from about 2.0% to about 9.0% of propylene glycol; (iv) from about 0.05% to about 0.50% of tetrasodium EDTA; (v) from about 0.05% to about 0.5% citric acid; (vi) from about 5% to about 15% lanolin oil; (vii) from about 3% to about 10% of cetyl alcohol; (viii) from about 1% to about 5% of stearyl alcohol; (ix) from about 0.5% to about 2.5% of beeswax, (x) from about 1.0% to about 7.0% of cod liver oil; (xi) from about 0.1% to about 1.0% of butylated hydroxytoluene; (xii) from about 0.05% to about 0.50% of St. John's wort extract; (xiii) from about 0.05% to about 0.50% of witch hazel extract; (xiv) from about 0.05% to about 0.5% of chamomile extract; (xv) from about 0.05% to about 0.5% of arnica extract; (xvi) from about 0.1% to about 0.5% of methylparaben; (xvii) from about 0.1% to about 0.5% of propylparaben (xviii) from about 0.50% to about 2% of allantoin; and (xix) from about 0.05% to about 0.50% of fragrance; wherein the pH of the emulsion is from about 3.0 to about 6.0, the allantoin being stable in the emulsion for at least 90 days at 40° C.; and(b) a flexible element that adsorbs or absorbs the emulsion such that the emulsion is applied to the skin of a patient on whom the flexible applicator is placed. 3. The flexible applicator system of claim 2 wherein the pH of the emulsion is from about 4.5 to about 5.8.4. A flexible applicator system for applying an oil-in-water emulsion comprising:(a) an oil-in-water emulsion comprising: (i) from about 55% to about 75% water; (ii) from about 1.0% to about 2.5% of 30% sodium lauryl sulfate; (iii) from about 3.0% to about 6.0% of propylene glycol; (iv) from about 0.1% to about 0.3% of tetrasodium EDTA; (v) from about 0.08% to about 0.35% citric acid; (vi) from about 8% to about 12% lanolin oil; (vii) from about 3.5% to about 7.5% of cetyl alcohol; (viii) from about 1.0% to about 3.0% of stearyl alcohol; (ix) from about 1.0% to about 2.5% of beeswax, (x) from about 1.0% to about 4.0% of cod liver oil; (xi) from about 0.2% to about 0.8% of butylated hydroxytoluene; (xii) from about 0.05% to about 0.15% of St. John's wort extract; (xiii) from about 0.05% to about 0.15% of witch hazel extract; (xiv) from about 0.05% to about 0.15% of chamomile extract; (xv) from about 0.05% to about 0.15% of arnica extract; (xvi) from about 0.15% to about 0.40% of methylparaben; (xvii) from about 0.10% to about 0.30% of propylparaben (xviii) from about 0.50% to about 2.0% of allantoin; and (xix) from about 0.1% to about 0.3% of fragrance; wherein the pH of the emulsion is from about 3.0 to about 6.0, the allantoin being stable in the emulsion for at least 90 days at 40°C.; and(b) a flexible element that adsorbs or absorbs the emulsion such that the emulsion is applied to the skin of a patient on whom the flexible applicator is placed. 5. The flexible applicator system of claim 4 wherein the pH of the emulsion is from about 4.5 to about 5.8.6. A flexible applicator system for applying an oil-in-water emulsion comprising:(a) an oil-in-water emulsion comprising: (i) about 68.68% water; (ii) about 1.9% of 30% sodium lauryl sulfate; (iii) about 5.3% of propylene glycol; (iv) about 0.15% of tetrasodium EDTA; (v) about 0.12% citric acid; (vi) about 10.6% lanolin oil; (vii) about 4.2% of cetyl alcohol; (viii) about 2.0% of stearyl alcohol; (ix) about 1.90% of beeswax, (x) about 2.0% of cod liver oil; (xi) about 0.5% of butylated hydroxytoluene; (xii) about 0.1% of St. John's wort extract; (xiii) about 0.1% of witch hazel extract; (xiv) about 0.1% of chamomile extract; (xv) about 0.1% of arnica extract; (xvi) about 0.3% of methylparaben; (xvii) about 0.25% of propylparaben (xviii) about 1.50% of allantoin; and (xix) about 0.20% of fragrance; wherein the pH of the emulsion is from about 3.0 to about 6.0, the allantoin being stable in the emulsion for at least 90 days at 40°C.; and(b) a flexible element that adsorbs or absorbs the emulsion such that the emulsion is applied to the skin of a patient on whom the flexible applicator is placed. 7. The flexible applicator system of claim 6 wherein the pH of the emulsion is from about 4.5 to about 5.8.8. The flexible applicator system of claim 1 wherein the flexible element is in the form of a bandage.9. The flexible applicator system of claim 2 wherein the flexible element is in the form of a bandage.10. The flexible applicator system of claim 4 wherein the flexible element is in the form of a bandage.11. The flexible applicator system of claim 6 wherein the flexible element is in the form of a bandage.12. The flexible applicator system of claim 1 wherein the flexible element is in the form of a wipe.13. The flexible applicator system of claim 2 wherein the flexible element is in the form of a wipe.14. The flexible applicator system of claim 4 wherein the flexible element is in the form of a wipe.15. The flexible applicator system of claim 6 wherein the flexible element is in the form of a wipe.16. The flexible applicator system of claim 1 wherein the flexible element is formed of a material selected from the group consisting of cotton, gauze, cellulose, nylon, rayon, a non-woven fabric, and a plastic polymer.17. The flexible applicator system of claim 2 wherein the flexible element is formed of a material selected from the group consisting of cotton, gauze, cellulose, nylon, rayon, a non-woven fabric, and a plastic polymer.18. The flexible applicator system of claim 4 wherein the flexible element is formed of a material selected from the group consisting of cotton, gauze, cellulose, nylon, rayon, a non-woven fabric, and a plastic polymer.19. The flexible applicator system of claim 6 wherein the flexible element is formed of a material selected from the group consisting of cotton, gauze, cellulose, nylon, rayon, a non-woven fabric, and a plastic polymer.