초록 ▼

The present invention relates to a tissue grafting material that includes a first tissue element harvested from an individual, a carrier, and a therapeutic substance contained in the carrier. The carrier and therapeutic substance are incorporated into the first tissue element and the first tissue el

The present invention relates to a tissue grafting material that includes a first tissue element harvested from an individual, a carrier, and a therapeutic substance contained in the carrier. The carrier and therapeutic substance are incorporated into the first tissue element and the first tissue element, carrier, and therapeutic substance form a unitary implant.

대표청구항 ▼

1. An implantable device comprising:a first tissue element harvested from an individual and containing tissue of a first tissue type; a second tissue element harvested from an individual and containing tissue of a second type differing from the first tissue type; a carrier; and a therapeutic substan

1. An implantable device comprising:a first tissue element harvested from an individual and containing tissue of a first tissue type; a second tissue element harvested from an individual and containing tissue of a second type differing from the first tissue type; a carrier; and a therapeutic substance contained in the carrier, where the implantable device is made by pressing together the first tissue element, second tissue element, carrier and therapeutic substance in a closed forming chamber having a configuration such that the first tissue element, second tissue element, carrier, and therapeutic substance form a unitary implant with the first tissue element compressed around the second tissue element and having a configuration corresponding to the configuration of the forming chamber. 2. The implantable device of claim 1 wherein the therapeutic substance is selected from a group which consists of antibiotics, bone growth enhancers, tricalcium phosphate, fibrin, allograft material and autograft material.3. The implantable device of claim 2 wherein the therapeutic substance is a bone growth enhancer.4. The implantable device of claim 3 wherein the first tissue element is bone tissue.5. The implantable device of claim 4 wherein the implant has a predetermined shape prior to implantation in a patient.6. The implantable device of claim 5 wherein the carrier is a gelatin or a polysaccharide.7. The implantable device of claim 5 wherein the bone tissue is viable.8. The implantable device of claim 5 further including a retainer at least partially enclosing the implant.9. The implantable device of claim 8 wherein the retainer has openings to enable tissue to grow through the openings after the device is implanted in a patient.10. The implantable device of claim 8 wherein the retainer is made of an expandable material.11. The implantable device of claim 10 wherein the retainer is made of a material that expands upon contact with body fluids.12. The implantable device of claim 8 wherein the retainer is made of PEEK.13. The implantable device of claim 8 wherein the retainer is made of a biodegradable material.14. The implantable device of claim 8 wherein the retainer is made of an allograft.15. The implantable device of claim 8 wherein the retainer is a cage.