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Methods and devices for providing prolonged drug therapy 원문보기

IPC분류정보
국가/구분 United States(US) Patent 등록
국제특허분류(IPC7판)
  • A61K-031/235
출원번호 US-0802709 (2001-03-08)
§371/§102 date 20020708 (20020708)
발명자 / 주소
  • Lam, Andrew C.
  • Shivanand, Padmaja
  • Ayer, Atul D.
  • Hatamkhany, Zahedeh
  • Gupta, Suneel K.
  • Guinta, Diane R.
  • Christopher, Carol A.
  • Saks, Samuel R.
  • Hamel, Lawrence G.
  • Wright, Jeri D.
  • Weyers, Richar
출원인 / 주소
  • Alza Corporation
대리인 / 주소
    Woodcock Washburn LLP
인용정보 피인용 횟수 : 87  인용 특허 : 46

초록

Methods and devices for maintaining a desired therapeutic drug effect over a prolonged therapy period are provided. In particular, oral dosage forms that release drug within the gastrointestinal tract at an ascending release rate over an extended time period are provided. The dosage forms may additi

대표청구항

1. A method for treating Attention-Deficit Disorder or Attention-Deficit Hyperactivity Disorder in a patient, wherein the method comprises administering a pharmaceutically acceptable composition comprising methylphenidate and a pharmaceutically acceptable carrier to said patient in a manner that ach

이 특허에 인용된 특허 (46)

  1. Misra Manjit K. (Ames IA) Shyy Yuh-Yuan (Ames IA), Acoustic and video imaging system for quality determination of pharmaceutical products.
  2. Saunders Richard J. (San Jose CA) Mefferd Wayne Sherman (Los Altos Hills CA), Apparatus for tracking moving workpiece by a laser beam.
  3. Weier Detlef (Heiligenberg DEX), Automatic sorting machine for sorting and classifying small products of the pharmaceutical and confectionery industries.
  4. Jacobs Richard L. ; Shah Shirish A., Caplet and gelatin covering therefor.
  5. Hampton Douglas B. (Holland MI) Tilton George W. (Grand Haven MI) Jordan Maureen L. (Allegan MI), Capsule-shaped tablet.
  6. Dante Lee G. (Merion Station PA), Composition and method of treating depression using natoxone or naltrexone in combination with a serotonin reuptake inhi.
  7. Mehta Atul M. (252 E. Crescent Ave. Ramsey NJ 07446), Controlled release indomethacin.
  8. Wong Patrick S. L. (Palo Alto CA) Barclay Brian L. (Sunnyvale CA) Deters Joseph C. (Los Altos CA) Theeuwes Felix (Los Altos CA), Controlled-release system with constant pushing source.
  9. Mehta Atul M. ; Zeitlin Andrew L. ; Dariani Maghsoud M., Delivery of multiple doses of medications.
  10. Urquhart John (Palo Alto CA) Theeuwes Felix (Los Altos CA), Delivery system comprising means for shielding a multiplicity of reservoirs in selected environment of use.
  11. Jordan Maureen L. (Mt. View CA) Ayer Atul D. (Palo Alto CA) Magruder Paul R. (Palo Alto CA) Edgren David E. (El Granada CA), Dosage form comprising fast agent delivery followed by slow agent delivery.
  12. Wright Jeremy C. (Los Altos CA) Guittard George V. (Cupertino CA), Dosage form for delivering drug to the intestine.
  13. Ayer Atul D. (Palo Alto CA) Swanson David R. (Palo Alto CA) Kuczynski Anthony L. (Palo Alto CA), Dosage form for treating cardiovascular diseases.
  14. Choi ; Nam Sok ; Heller ; Jorge, Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates).
  15. Urquhart John (Palo Alto CA) Theeuwes Felix (Los Altos CA), Drug delivery system comprising a reservoir containing a plurality of tiny pills.
  16. Hoover Charles E. (Sparta NJ) Dennin Randy J. (Greenwood SC) Gabor E. Allan (Summit NJ) Schobel Mark (Flemington NJ) Sorg Albert F. (Columbia NJ), Encapsulated dosage forms.
  17. Edgren David Emil ; Skluzacek Robert Raymond ; Barclay Brian L. ; Bhatti Gurdish Kaur, Exit means in dosage form.
  18. Horacek H. Joseph (P.O. Box 470144 Charlotte NC 28247), Extended release clonidine formulation.
  19. Riddle Thomas A. (San Francisco CA) Geerke Johan H. (Los Altos CA) Minton Keith P. (San Jose CA), Laser tablet treatment system with dual access to tablet.
  20. Riddle Thomas A. (San Francisco CA) Geerke Johan H. (Los Altos CA) Minton Keith P. (San Jose CA), Laser tablet treatment system with dual access to tablet.
  21. Nagashima Jiro (Chiba JPX) Utsunomiya Masatoshi (Narashino JPX) Suzuki Norimichi (Chiba JPX) Nakamura Kazuhiko (Hasuda JPX), Method and apparatus for determination of ingredients of tablets.
  22. Wong Patrick S.-L. ; Theeuwes Felix ; Ayer Atul Devdatt ; Kuczynski Anthony L., Method for administering drug to gastrointestinal tract.
  23. Theeuwes Felix (Los Altos CA), Method for adminstering tiny pills.
  24. Chien Yie W. (Skokie IL) Lambert Howard J. (Deerfield IL), Method for making a microsealed delivery device.
  25. Wong Patrick S.-L. ; Theeuwes Felix ; Guittard George V. ; Ayer Atul D., Method of therapy comprising an osmotic caplet.
  26. Maruyama Frederick (San Jose CA) Cortese Richard (Los Gatos CA), Multi-unit pulsatile delivery system.
  27. Benedikt ; Gerald, New oral form of medicament and a method for producing it.
  28. Wong Patrick S. L. (Hayward CA) Barclay Brian (Sunnyvale CA) Deters Joseph C. (Mt. View CA) Theeuwes Felix (Los Altos CA), Osmotic device with dual thermodynamic activity.
  29. Cortese Richard (San Jose CA) Theeuwes Felix (Los Altos CA), Osmotic device with hydrogel driving member.
  30. Edgren David (El Granada CA), Osmotic device with wall comprising cellulose ether and permeability enhancer.
  31. Theeuwes Felix (Los Altos CA), Osmotic dispenser with gas generating means.
  32. Wong Patrick S.-L. (Hayward CA) Barclay Brian L. (Sunnyvale CA) Oeters Joseph C. (Mountain View CA) Theeuwes Felix (Los Altos CA), Osmotic system comprising plurality of members for dispensing drug.
  33. Theeuwes ; Felix, Osmotic system for delivering selected beneficial agents having varying degrees of solubility.
  34. Theeuwes ; Felix, Osmotic system for the controlled and delivery of agent over time.
  35. Ayer Atul D. (Mountain View CA) Theeuwes Felix (Los Altos CA), Osmotic system with distribution zone for dispensing beneficial agent.
  36. Choi ; Nam Sok ; Heller ; Jorge, Poly(carbonates).
  37. Schmitt ; Edward Emil, Poly(orthoester) co- and homopolymers and poly(orthocarbonate) co- and homopolymers having carbonyloxy functionality.
  38. Capozza ; Richard C., Polymeric orthoesters housing beneficial drug for controlled release therefrom.
  39. Theeuwes ; Felix ; Saunders ; Richard J. ; Mefford ; Wayne S., Process for forming outlet passageways in pills using a laser.
  40. Ayer Atul D. (Mountain View CA) Theeuwes Felix (Los Altos CA), Process for manufacturing device with dispersion zone.
  41. Dong Liang C. ; Wong Patrick S. L. ; Espinal Steven, Progesterone replacement therapy.
  42. Cortese Richard (San Jose CA) Barclay Brian (Menlo Park CA) Theeuwes Felix (Los Altos CA), Simultaneous delivery of two drugs from unit delivery device.
  43. Michaels Alan S. (Atherton CA), Structured bioerodible drug delivery device.
  44. Sheth Pravin (Springfield NJ) Leeson Lewis J. (Roseland NJ), Sustained action dosage forms.
  45. Ayer Atul Devatt ; Yieh Richard L.-C. ; Pollock Brenda J. ; Wong Patrick S.-L., Sustained antiepileptic therapy.
  46. Baker Helen Frances,GBX ; Gilbert Julian Clive,GBX, Sustained-release formulation of methylphenidate.

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  2. Bozik, Michael E.; Petzinger, Jr., Thomas; Mather, James L.; Archibald, Donald, Compositions and methods for treating amyotrophic lateral sclerosis in responders.
  3. Bozik, Michael E.; Dworetzky, Steven, Compositions and methods for treating chronic urticaria.
  4. Bozik, Michael E; Dworetzky, Steven, Compositions and methods for treating chronic urticaria.
  5. Bozik, Michael E.; Hebrank, Gregory; Farwell, Wildon; Petzinger, Jr., Thomas; Dworetzky, Steven, Compositions and methods for treating conditions related to increased eosinophils.
  6. Bozik, Michael E.; Dworetzky, Steven, Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders.
  7. Bozik, Michael E.; Dworetzky, Steven, Compositions and methods for treating plasma cell disorders and B-cell prolymphocytic disorders.
  8. Bozik, Michael E.; Gribkoff, Valentin; Petzinger, Jr., Thomas, Compositions and methods of using (R)-pramipexole.
  9. Bozik, Michael E.; Petzinger, Jr., Thomas; Gribkoff, Valentin, Compositions and methods of using (R)-pramipexole.
  10. Lickrish, David; Zhang, Feng, Compositions for treatment of attention deficit hyperactivity disorder.
  11. Lickrish, David; Zhang, Feng, Compositions for treatment of attention deficit hyperactivity disorder.
  12. Lickrish, David; Zhang, Feng, Compositions for treatment of attention deficit hyperactivity disorder.
  13. Lickrish, David; Zhang, Feng, Compositions for treatment of attention deficit hyperactivity disorder.
  14. Lickrish, David; Zhang, Feng, Compositions for treatment of attention deficit hyperactivity disorder.
  15. Lickrish, David; Zhang, Feng, Compositions for treatment of attention deficit hyperactivity disorder.
  16. Lickrish, David; Zhang, Feng, Compositions for treatment of attention deficit hyperactivity disorder.
  17. Lickrish, David; Zhang, Feng, Compositions for treatment of attention deficit hyperactivity disorder.
  18. Lickrish, David; Zhang, Feng, Compositions for treatment of attention deficit hyperactivity disorder.
  19. Bozik, Michael E.; Petzinger, Jr., Thomas; Gribkoff, Valentin, Compositions of R(+) and S(−) pramipexole and methods of using the same.
  20. Bozik, Michael E.; Petzinger, Jr., Thomas; Gribkoff, Valentin, Compositions of R(+) and S(−) pramipexole and methods of using the same.
  21. Yum, Su Il; Chao, Wendy; Su, Huey-Ching; Fu, Roger; Zamloot, Michael S.; Bratin, Karl; Shanker, Ravi M., Compositions with a rheological modifier to reduce dissolution variability.
  22. Yum, Su Il; Chao, Wendy; Su, Huey-Ching; Fu, Roger; Zamloot, Michael S.; Bratin, Karl; Shanker, Ravi M., Compositions with a rheological modifier to reduce dissolution variability.
  23. Yum, Su Il; Chao, Wendy; Su, Huey-Ching; Fu, Roger; Zamloot, Michael S.; Bratin, Karl; Shanker, Ravi M., Compositions with a rheological modifier to reduce dissolution variability.
  24. Yum, Su Il; Chao, Wendy; Su, Huey-Ching; Fu, Roger; Zamloot, Michael S.; Bratin, Karl; Shanker, Ravi M., Compositions with a rheological modifier to reduce dissolution variability.
  25. Benedetti, Hernan D.; Franco, Cristian R.; Bigatti, Guido S.; Faour, Joaquina; Pastini, Ana C., Dose-dumping resistant controlled release dosage form.
  26. Benedetti, Hernan D.; Franco, Cristian R.; Bigatti, Guido S.; Faour, Joaquina; Pastini, Ana C., Dose-dumping resistant controlled release dosage form.
  27. Benedetti, Hernan D.; Franco, Cristian R.; Bigatti, Guido S.; Faour, Joaquina; Pastini, Ana C., Dose-dumping resistant controlled release dosage form.
  28. Lickrish, David; Zhang, Feng, Method of treatment of attention deficit hyperactivity disorder.
  29. Lickrish, David; Zhang, Feng, Methods and compositions for treatment of attention deficit disorder.
  30. Gupta, Suneel K.; Guinta, Diane R.; Christopher, Carol A.; Saks, Samuel R.; Hamel, Lawrence G., Methods and devices for providing prolonged drug therapy.
  31. Gupta, Suneel K.; Guinta, Diane R.; Christopher, Carol A.; Saks, Samuel R.; Hamel, Lawrence G., Methods and devices for providing prolonged drug therapy.
  32. Gupta, Suneel K.; Guinta, Diane R; Christopher, Carol A.; Saks, Samuel R.; Hamel, Lawrence G., Methods and devices for providing prolonged drug therapy.
  33. Lam, Andrew C.; Shivanand, Padmaja; Ayer, Atul D.; Hatamkhany, Zahedeh; Gupta, Suneel K.; Guinta, Diane R.; Christopher, Carol A.; Saks, Samuel R.; Hamel, Lawrence G.; Wright, Jeri D.; Weyers, Richard G., Methods and devices for providing prolonged drug therapy.
  34. Yam, Nyomi V.; Reyes, Iran; Davar, Nipun; Ayer, Atul D.; Lee, Julie; Seroff, Sonya; Gupta, Suneel K.; Sathyan, Gayatri, Methods and dosage forms for controlled delivery of paliperidone and risperidone.
  35. Lickrish, David; Zhang, Feng, Methods for treatment of attention deficit hyperactivity disorder.
  36. Lickrish, David; Zhang, Feng, Methods for treatment of attention deficit hyperactivity disorder.
  37. Lickrish, David; Zhang, Feng, Methods for treatment of attention deficit hyperactivity disorder.
  38. Lickrish, David; Zhang, Feng, Methods of treatment of attention deficit hyperactivity disorder.
  39. Bozik, Michael E.; Petzinger, Jr., Thomas; Gribkoff, Valentin, Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same.
  40. Dixit, Manesh; Chen, Chih-Ming; Cheng, Xiu Xiu; Xie, Jianbo, Oral controlled release dosage form.
  41. Dixit, Manesh; Chen, Chih-Ming; Cheng, Xiu-Xiu; Xie, Jianbo, Oral controlled release dosage form.
  42. Yum, Su Il; Schoenhard, Grant; Tipton, Arthur J.; Gibson, John W.; Middleton, John C., Oral drug delivery system.
  43. Yum, Su Il; Schoenhard, Grant; Tipton, Arthur J.; Gibson, John W.; Middleton, John C., Oral drug delivery system.
  44. Yum, Su Il; Schoenhard, Grant; Tipton, Arthur J.; Gibson, John W.; Middleton, John C.; Fu, Roger; Zamloot, Michael S., Oral drug delivery system.
  45. Yum, Su Il; Schoenhard, Grant; Tipton, Arthur J.; Gibson, John W.; Middleton, John C.; Fu, Roger; Zamloot, Michael S., Oral drug delivery system.
  46. Yum, Su Il; Schoenhard, Grant; Tipton, Arthur J.; Gibson, John W.; Middleton, John C.; Fu, Roger; Zamloot, Michael S., Oral drug delivery system.
  47. Yum, Su Il; Chao, Wendy; Su, Huey-Ching; Fu, Roger; Zamloot, Michael, Oral pharamaceutical dosage forms.
  48. Scicinski, Jan J.; van Osdol, William W.; Su, Huey-Ching; Arenberg, Michael H.; Shah, Jaymin, Oral pharmaceutical dosage forms.
  49. Scicinski, Jan J.; van Osdol, William W.; Su, Huey-Ching; Arenberg, Michael H.; Shah, Jaymin, Oral pharmaceutical dosage forms.
  50. Yum, Su Il; Chao, Wendy; Su, Huey-Ching; Fu, Roger; Zamloot, Michael, Oral pharmaceutical dosage forms.
  51. Yum, Su Il; Chao, Wendy; Su, Huey-Ching; Fu, Roger; Zamloot, Michael, Oral pharmaceutical dosage forms.
  52. Kramer, Dirk; Rey, Helene; Scheer, Mathias, Pharmaceutical dosage form.
  53. Fleshner-Barak, Moshe; Lerner, E. Itzhak; Rosenberger, Vered; Dahan, Mazal; Makov, Yisrael, Rapidly expanding composition for gastric retention and controlled release of therapeutic agents, and dosage forms including the composition.
  54. Chen, Weirong; Humora, Michael; Kwok, Daw-Iong Albert; Kiesman, William F.; Irdam, Erwin Ayandra, Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds.
  55. Chen, Weirong; Humora, Michael; Kwok, Daw-long Albert; Kiesman, William F.; Irdam, Erwin Ayandra, Synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds.
  56. Raje, Prasad; Gadikota, Rajendrakumar Reddy; Chen, Jian-Xie; Lapina, Olga V.; McCall, John M., Synthesis of chirally purified substituted benzothiazole diamines.
  57. Raje, Prasad; Gadikota, Rajendrakumar Reddy; Chen, Jian-Xie; Lapina, Olga V.; McCall, John M., Synthesis of chirally purified substituted benzothiazole diamines.
  58. McKenna, William H.; Mannion, Richard O.; O'Donnell, Edward P.; Huang, Haiyong H., Tamper resistant dosage forms.
  59. McKenna, William H.; Mannion, Richard O.; O'Donnell, Edward P.; Huang, Haiyong H., Tamper resistant dosage forms.
  60. McKenna, William H.; Mannion, Richard O.; O'Donnell, Edward P.; Huang, Haiyong H., Tamper resistant dosage forms.
  61. McKenna, William H.; Mannion, Richard O.; O'Donnell, Edward P.; Huang, Haiyong H., Tamper resistant dosage forms.
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  66. McKenna, William H.; Mannion, Richard O.; O'Donnell, Edward P.; Huang, Haiyong H., Tamper resistant dosage forms.
  67. McKenna, William H.; Mannion, Richard O.; O'Donnell, Edward P.; Huang, Haiyong H., Tamper resistant dosage forms.
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  81. McKenna, William H.; Mannion, Richard O.; O'Donnell, Edward P.; Huang, Haiyong H., Tamper resistant dosage forms.
  82. McKenna, William H.; Mannion, Richard O.; O'Donnell, Edward P.; Huang, Haiyong H., Tamper resistant dosage forms.
  83. McKenna, William H.; Mannion, Richard O.; O'Donnell, Edward P.; Huang, Haiyong H., Tamper resistant dosage forms.
  84. McKenna, William H.; Mannion, Richard O.; O'Donnell, Edward P.; Huang, Haiyong H., Tamper resistant dosage forms.
  85. McKenna, William H.; Mannion, Richard O.; O'Donnell, Edward P.; Huang, Haiyong H., Tamper resistant dosage forms.
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